Вопросы вирусологии. 2020; 65: 243-258
Формирование популяционного генофонда потенциально угрожающих биобезопасности зоонозных вирусов
https://doi.org/10.36233/0507-4088-2020-65-5-1Аннотация
Коронавирусы начали формировать генофонд, взаимодействуя с земноводными (подсемейство Letovirinae), но в основном с рукокрылыми (Chiroptera) в третичном периоде (110–85 млн лет назад), образуя также переход на парнопалых (эоцен, 70–60 млн лет назад) и лишь 10–2 тыс. лет до н.э. приобретя способность к респираторной передаче (в первую очередь, вероятно, представителями рода Alphacoronavirus), обособились в сезонную инфекцию людей. Подобная ситуация возможна в ближайшем будущем с SARS-CoV-2. Эпидемические катаклизмы, более серьезные, чем COVID-19, связанные с зоонозными вирусами, вероятно, возникнут и в будущем. Необходим постоянный мониторинг популяционных генофондов зоонозных вирусов.
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Problems of Virology. 2020; 65: 243-258
Formation of population gene pools of zoonotic viruses, potentially threatening biosafety
https://doi.org/10.36233/0507-4088-2020-65-5-1Abstract
Coronaviruses formed a gene pool by interaction with Amphibia (subfamily Letovirinae) and then with Chiroptera in Tertiary (110–75 million years ago) with transformation to Artiodactyla (Eocene – 70–60 million years ago), and only 10–2 thousand years BC acquired the ability to a respiratory transmission and became Alphaviruses, a seasonal infection of humans. A similar situation is possible in the near future with SARS-CoV-2. Pandemics associated with zoonoses even more serious than COVID-19 are likely. Constant monitoring of populational gene pools of zoonotic viruses is necessary.
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