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Вопросы вирусологии. 2018; 63: 197-201

ПЛАЗМИДЫ АРХЕЙ КАК ВОЗМОЖНЫЕ ПРЕДКИ ДНК-СОДЕРЖАЩИХ ВИРУСОВ

Львов Д. К., Сизикова Т. Е., Лебедев В. Н., Борисевич С. В.

https://doi.org/10.18821/0507-4088-2018-63-5-197-201

Аннотация

Царство Археи (Arhaea) наряду с бактериями (Bacteria) относятся к надцарству Procaryota. Солелюбивые археи (Halorubrum lacusprofundi), изолированные из солевых озер Антарктиды, содержат плазмиды (pR1SE), которые кодируют белки, участвующие в формировании стенок везикул архей. В настоящем обзоре представлены данные о молекулярно-генетических и биологических свойствах плазмиды pR1SE и особенностях взаимодействия плазмид с чувствительными клетками архей. Особое внимание обращено на роль структурных белков, кодируемых плазмидой pR1SE, в процессе формирования мембранного комплекса везикул. Везикулы архей, содержащие плазмиды, моделируют некоторые свойства вирусов. Плазмиды архей могут рассматриваться как возможные предки ДНК-содержащих вирусов.
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Problems of Virology. 2018; 63: 197-201

PLASMIDS OF ARCHAEA AS POSSIBLE ANCESTORS OF DNA-CONTAINING VIRUSES

Lvov D. K., Sizikova T. E., Lebedev V. N., Borisevich S. V.

https://doi.org/10.18821/0507-4088-2018-63-5-197-201

Abstract

Тhе kingdom Archaea, as well as Bacteria, belongs to the overkingdom Prokaryota. Halophilic archaea (Halorubrum lacusprofundi) isolated from Antarctic saline lakes contain plasmids (pR1SE) that code proteins taking part in the formation of membranes of archaea vesicles. The molecular and biological properties of pR1SE and the peculiarity of its interaction with sensitive cells are considered in this article. The role of structural proteins coded by pR1S in the process of formation of vesicle membrane complex is paid special attention. Plasmid-containing archaea vesicles model some properties of viruses. Archaea plasmids can be viewed as possible ancestors of DNA-containing viruses.
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22. Claverie J.M., Abergel C. Giant viruses: The difficult breaking of multiple epistemological barriers. Stud. Hist. Philos. Biol. Biomed. Sci. 2016; 59: 89-99.