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Акушерство и Гинекология Санкт-Петербурга. 2020; : 35-38

Серозный рак эндометрия – редкая эпителиальная опухоль матки

Ульрих Е. А., Нейштадт Э. В., Урманчеева А. Ф., Кутушева Г. Ф.

Аннотация

Серозный рак эндометрия является лидером среди редких эпителиальных опухолей тела матки и характеризуется неблагоприятным прогнозом. Учитывая агрессивное поведение данного новообразования, требуется адекватный объем хирургического вмешательства, включающий гистераднексэктомию, тазовую, парааортальную лимфаденэктомию, оментэктомию и полноценное адъювантное лечение, включающее лучевую и химиотерапию.
Список литературы

1. Kurman R.J., Carcangiu M.L., Harrington C.S., Young R.H. et al. WHO Classification of Tumors of the Female Reproductive Organs. World Health Organization Classification of Tumors. 4th edn. Geneva, Switzerland: WHO Press; 2014.

2. Ульрих Е.А., Нейштадт Э.Л.Редкиеформыракателаматки. Практическая онкология. 2004; 5 (1 (17)): 68–76.

3. Novak E. Gynecologycal and Obstetrical Pathology. Philadelphia: WB Saunders; 1947. P. 225–241.

4. Hendrickson M., Ross J., Eifel P., Martinez A., Kempson R. Uterine papillary serous carcinoma: a highly malignant form of endometrial adenocarcinoma. Am J Surg Pathol. 1982 Mar; 6 (2): 93–108.

5. de Jonge M.M., Mooyaart A.L., Vreeswijk M.P., de Kroon C.D., van Wezel T., van Asperen C.J. et al. Linking uterine serous carcinoma to BRCA1/2-associated cancer syndrome: A meta-analysis and case report. Eur J Cancer. 2017 Feb; 72: 215–225.

6. Bancher-Todesca D., Neunteufel W., Williams K.E., Prainsack D., Breitenecker G., Friedlander M.L. et al. Influence of postoperative treatment on survival in patients with uterine papillary serous carcinoma. Gynecol Oncol. 1998 Dec; 71 (3): 344–7.

7. Kandoth C., Schultz N., Cherniack A.D., Akbani R., Liu Y., Shen H. et al. The Cancer Genome Atlas Research Network. Integrated genomic characterization of endometrial carcinoma. Nature. 2013; 497 (7447): 67–73. doi:10.1038/nature12113.

8. de Boer S.M., Powell M.E., Mileshkin L., Creutzberg C.L. et al. PORTEC Study Group. Adjuvant chemoradiotherapy versus radiotherapy alone in women with high-risk endometrial cancer (PORTEC-3): patterns of recurrence and post-hoc survival analysis of a randomised phase 3 trial. Lancet Oncol. 2019 Sep; 20 (9): 1273–1285.

9. Fader A.N., Roque D.M., Siegel E. et al. Randomized Phase II Trial of CarboplatinPaclitaxel Compared with Carboplatin-Paclitaxel-Trastuzumab in Advanced (Stage III–IV) or Recurrent Uterine Serous Carcinomas that Overexpress Her2/Neu (NCT01367002): Updated Overall Survival Analysis. Clin Cancer Res. 2020 Aug 1; 26 (15): 3928–3935.

Obstetrics and Gynaecology of Saint-Petersburg. 2020; : 35-38

Serous endometrial cancer – a rare epithelial tumor of the uterus

Ulrikh E. A., Neistadt E. V., Urmancheeva A. F., Kutusheva G. F.

Abstract

Uterine Serous Cancer is the leader among rare uterine epithelial neoplasms and has unfavorable prognosis. An adequate surgical treatment is required, including hysteradnexectomy, pelvic, paraaortal lymphadenectomy, omentectomy, and sufficient adjuvant treatment, including radiation and chemotherapy.
References

1. Kurman R.J., Carcangiu M.L., Harrington C.S., Young R.H. et al. WHO Classification of Tumors of the Female Reproductive Organs. World Health Organization Classification of Tumors. 4th edn. Geneva, Switzerland: WHO Press; 2014.

2. Ul'rikh E.A., Neishtadt E.L.Redkieformyrakatelamatki. Prakticheskaya onkologiya. 2004; 5 (1 (17)): 68–76.

3. Novak E. Gynecologycal and Obstetrical Pathology. Philadelphia: WB Saunders; 1947. P. 225–241.

4. Hendrickson M., Ross J., Eifel P., Martinez A., Kempson R. Uterine papillary serous carcinoma: a highly malignant form of endometrial adenocarcinoma. Am J Surg Pathol. 1982 Mar; 6 (2): 93–108.

5. de Jonge M.M., Mooyaart A.L., Vreeswijk M.P., de Kroon C.D., van Wezel T., van Asperen C.J. et al. Linking uterine serous carcinoma to BRCA1/2-associated cancer syndrome: A meta-analysis and case report. Eur J Cancer. 2017 Feb; 72: 215–225.

6. Bancher-Todesca D., Neunteufel W., Williams K.E., Prainsack D., Breitenecker G., Friedlander M.L. et al. Influence of postoperative treatment on survival in patients with uterine papillary serous carcinoma. Gynecol Oncol. 1998 Dec; 71 (3): 344–7.

7. Kandoth C., Schultz N., Cherniack A.D., Akbani R., Liu Y., Shen H. et al. The Cancer Genome Atlas Research Network. Integrated genomic characterization of endometrial carcinoma. Nature. 2013; 497 (7447): 67–73. doi:10.1038/nature12113.

8. de Boer S.M., Powell M.E., Mileshkin L., Creutzberg C.L. et al. PORTEC Study Group. Adjuvant chemoradiotherapy versus radiotherapy alone in women with high-risk endometrial cancer (PORTEC-3): patterns of recurrence and post-hoc survival analysis of a randomised phase 3 trial. Lancet Oncol. 2019 Sep; 20 (9): 1273–1285.

9. Fader A.N., Roque D.M., Siegel E. et al. Randomized Phase II Trial of CarboplatinPaclitaxel Compared with Carboplatin-Paclitaxel-Trastuzumab in Advanced (Stage III–IV) or Recurrent Uterine Serous Carcinomas that Overexpress Her2/Neu (NCT01367002): Updated Overall Survival Analysis. Clin Cancer Res. 2020 Aug 1; 26 (15): 3928–3935.