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Рецепт. 2019; 22: 833-841

Анализ потребления антибиотиков для лечения внебольничной пневмонии в стационарах разного уровня

Каляда А. Н., Захаренко А. Г.

Аннотация

Целью исследования стало изучение особенностей назначения антибиотиков при внебольничной пневмонии (ВП) в стационарах разного уровня. Для решения поставленной задачи, было проведено ретроспективное исследование среди пациентов с ВП (507 выписанных), госпитализированных в стационары разного уровня в период с 1 января 2010 г. по 31 декабря 2010 г. В результате исследования были выявлены наиболее часто используемые антибиотики. В числе факторов, влияющих на течение ВП у взрослых госпитализированных пациентов, можно назвать неадекватное назначение антибиотиков по поводу ВП и недостаточное следование существующим клиническим рекомендациям при ведении пациентов с ВП в стационаре.

Список литературы

1. Chuchalin A., Sinopalnikov A., Kozlov R. (2018) Vnebol’nichnaya pnevmoniya u vzroslykh. Prakticheskie rekomendacii po diagnostike, lecheniyu i profi laktike [CAP in adults. Practice guidelines for diagnosis, treatment, and prevention]. Moscow. (in Russian)

2. (2005) Guidelines for management of adults with hospital-acquired, ventilator-associated and health-care associated pneumonia. Am. J. Respir. Crit. Care Med., vol. 171 (4), pp. 388–416.

3. (2008) Guidelines for the management of hospital-acquired pneumonia in the UK: Report of the Working Party on Hospital-Acquired Pneumonia of the British Society for Antimicrobial Chemotherapy.

4. Menendez R., Torres A., Zalacain R. (2004) Risk factors of treatment failure in community acquired pneumonia: implications for disease outcome. Thorax, vol. 59, pp. 960–5.

5. Rachina S., Kozlov R., Shal E., Nedorozenyuk I., Leshchenko I., Bochanova E. (2009) Analiz antibakterial’noj terapii gospitalizirovannykh pacientov s vnebol’nichnoj pnevmoniej v razlichnykh regionakh RF: uroki mnogocentrovogo farmakoe`pidemiologicheskogo issledovaniya [Analysis of antibiotic therapy in hospitalized patients with CAP in different regions of the Russian Federation: lessons of multicenter pharmacoepidemiological study]. Klinicheskaya mikrobiologiya i antimikrobnaya khimioterapiya, vol. 11(1), pp. 66–78.

6. Yakovlev S. (2002) Kriticheskij analiz antibakterial'nyh preparatov dlya isceleniya infekcij v stacionare [Critical analysis of antibacterial drugs for the treatment of infections in the hospital]. Consilium medicum, vol. 4, no 1, p. 2230.

7. Zubkov M. (2009) Sovremennye aspekty ehtiologicheskoj diagnostiki i antimikrobnoj terapii vnebol'nichnyh pnevmonij [Modern aspects of etiological diagnosis and antimicrobial therapy for community-acquired pneumonia]. Farmateka, no 19, pp. 23–28.

Recipe. 2019; 22: 833-841

The Analysis of Antibiotics Consumption for the Treatment of Community-Acquired Pneumonia in Different Level Hospitals

Kaliada A. , Zakharenko A.

Abstract

The aim of this study was to investigate features of antibiotics prescriptions for treatment of community-acquired pneumonia (CAP). A retrospective trial was performed to analyze treatment of adult patients with community-acquired pneumonia (CAP) that were hospitalized to different level hospitals from January 1, 2010 to December 31, 2010. The study involved 507 (all patients were discharged) in-patients with CAP. As a result, during the research the most often used antibiotics for treatment of CAP were revealed. Factors influencing the course of CAP in in-patient adults were inadequate antibacterial treatment and poor adherence to current guidelines for treatment of patients with CAP.

References

1. Chuchalin A., Sinopalnikov A., Kozlov R. (2018) Vnebol’nichnaya pnevmoniya u vzroslykh. Prakticheskie rekomendacii po diagnostike, lecheniyu i profi laktike [CAP in adults. Practice guidelines for diagnosis, treatment, and prevention]. Moscow. (in Russian)

2. (2005) Guidelines for management of adults with hospital-acquired, ventilator-associated and health-care associated pneumonia. Am. J. Respir. Crit. Care Med., vol. 171 (4), pp. 388–416.

3. (2008) Guidelines for the management of hospital-acquired pneumonia in the UK: Report of the Working Party on Hospital-Acquired Pneumonia of the British Society for Antimicrobial Chemotherapy.

4. Menendez R., Torres A., Zalacain R. (2004) Risk factors of treatment failure in community acquired pneumonia: implications for disease outcome. Thorax, vol. 59, pp. 960–5.

5. Rachina S., Kozlov R., Shal E., Nedorozenyuk I., Leshchenko I., Bochanova E. (2009) Analiz antibakterial’noj terapii gospitalizirovannykh pacientov s vnebol’nichnoj pnevmoniej v razlichnykh regionakh RF: uroki mnogocentrovogo farmakoe`pidemiologicheskogo issledovaniya [Analysis of antibiotic therapy in hospitalized patients with CAP in different regions of the Russian Federation: lessons of multicenter pharmacoepidemiological study]. Klinicheskaya mikrobiologiya i antimikrobnaya khimioterapiya, vol. 11(1), pp. 66–78.

6. Yakovlev S. (2002) Kriticheskij analiz antibakterial'nyh preparatov dlya isceleniya infekcij v stacionare [Critical analysis of antibacterial drugs for the treatment of infections in the hospital]. Consilium medicum, vol. 4, no 1, p. 2230.

7. Zubkov M. (2009) Sovremennye aspekty ehtiologicheskoj diagnostiki i antimikrobnoj terapii vnebol'nichnyh pnevmonij [Modern aspects of etiological diagnosis and antimicrobial therapy for community-acquired pneumonia]. Farmateka, no 19, pp. 23–28.