Рецепт. 2018; : 535-550
Механизмы развития и клинико-патогенетическое значение анемий при хронических воспалительных заболеваниях кишечника (язвенном колите и болезни Крона)
Аннотация
На основании проведенного исследования в статье представлены результаты анализа распространенности анемий у пациентов с воспалительными заболеваниями кишечника (ВЗК), оценка основных факторов риска развития анемии у пациентов с язвенным колитом (ЯК) и болезнью Крона (БК), показаны результаты исследования структуры анемий у пациентов с ВЗК в зависимости от патогенетического механизма их развития. С учетом полученных данных разработан алгоритм по диагностике и тактике терапии анемий у пациентов с ВЗК, адаптированный к условиям Республики Беларусь.
Список литературы
1. Alves R. [et al.] (2014) Anemia in infl ammatory bowel disease: prevalence, diff erential diagnosis and association with clinical and laboratory variables. Sao Paulo Medical Journal, vol. 132, no 3, pp. 140–146.
2. Weiss G. [et al.] (2010) Pathogenesis and treatment of anemia in Infl ammatory Bowel Disease. Haematologica, vol. 95, pp. 175–178.
3. Oustamanolakis P. [et al.] (2011) Diagnosing anemia in infl ammatory bowel disease: Beyond the established markers. Journal of Crohn’s and Colitis, vol. 5, no 5, pp. 381–391.
4. Gorgun YU., Karatish O., Portyanko A. (2007) Osobennosti korrektsii obmena zheleza pri hronicheskih vospalitel’nih zabolevaniyah kishechnika [Features of iron exchange correction in chronic infl ammatory bowel diseases]. Meditsinskie novosti, 11, pp. 82–84.
5. Murawska N. [et al.] (2016) Anemia of Chronic Disease and Iron Defi ciency Anemia in Infl ammatory Bowel Diseases: Pathophysiology, Diagnosis, and Treatment. Infl ammatory bowel diseases, vol. 22, no 5, pp. 1198–1208.
6. Basseri R. [et al.] (2013) Hepcidin is a key mediator of anemia of infl ammation in Crohn’s disease. Journal of Crohn’s and Colitis, vol. 7, no 8, pp. 286–291.
7. Armitage A. [et al.] (2011) Hepcidin regulation by innate immune and infectious stimuli. Blood, vol. 1, pp. 118–128.
8. Dignass A. [et al.] (2015) European Consensus on the Diagnosis and Management of Iron Defi ciency and Anaemia in Infl ammatory Bowel Diseases. Journal of Crohn’s and Colitis, vol. 1, pp. 1–12.
9. Oustamanolakis P. [et al.] (2011) Soluble transferrin receptor-ferritin index in the evaluation of anemia in infl ammatory bowel disease: a case-control study. Annals of Gastroenterology, vol. 24, no 2, pp. 108–114.
10. Abitbol V. [et al.] (2015) Diagnosis of Iron Defi ciency in Infl ammatory Bowel Disease by Transferrin Receptor-Ferritin Index. Medicine (Baltimore), vol. 94, no 26, pp. 98–105.
11. Kulnigg S. [et al.] (2008) A novel intravenous iron formulation for treatment of anemia in infl ammatory bowel disease: the ferric carboxymaltose [FERINJECT] randomized controlled trial. The American Journal of Gastroenterology, vol. 103, pp. 1182–1192.
12. Lee T. [et al.] (2012) Iron replacement therapy in infl ammatory bowel disease patients with iron defi ciency anemia: a systematic review and meta-analysis. Journal of Crohn’s and Colitis, vol. 6, pp. 267–275.
13. Kulnigg S. [et al.] (2006) Systematic review: managing anemia in Crohn’s disease. Alimentary Pharmacology & Therapeutics, vol. 24, pp. 1507–1523.
14. Weiss G. [et al.] (2005) Anemia of Chronic Disease. The New England Journal of Medicine, vol. 352, pp. 1011–1023.
15. WHO (1989) Preventing and controlling anemia through primary health care: a guide for health administrators and programme managers. Geneva, World Health Organization.
16. Wilson A. [et al.] (2004) Prevalence and outcomes of anemia in infl ammatory bowel disease: a systematic review of the literature. American Journal of Medicine, vol. 116, pp. 44–49.
17. Filmann N. [et al.] (2014) Prevalence of anemia in infl ammatory bowel diseases in European countries: a systematic review and individual patient data meta-analysis. Infl ammatory bowel diseases, vol. 20, no 12, pp. 936–945.
18. Koutroubakis I. [et al.] (2015) Persistent or recurrent anemia is associated with severe and disabling infl ammatory bowel disease. Clinical Gastroenterology and Hepatology, vol. 13, no 12, pp. 1760–1766.
19. Akhuemonkhan E. [et al.] (2017) Prevalence and screening for anemia in mild to moderate Crohn’s disease and ulcerative colitis in the United States, 2010–2014. BMJ Open Gastroenterology, vol. 4, no 1, pp. 1–8.
Recipe. 2018; : 535-550
Mechanisms of the development and clinico-pathological signifi cance of anemia in chronic infl ammatory bowel diseases (ulcerative colitis and Crohn’s disease)
Abstract
The prevalence of anemia in patients with infl ammatory bowel diseases in Belarus, factors risk for anemia and pathogenetic structure of anemia in patients with ulcerative colitis and Crohn’s disease are presented in article. The algorithm for the diagnosis and management of anemia in patients with IBD was developed based on the results of the study.
References
1. Alves R. [et al.] (2014) Anemia in infl ammatory bowel disease: prevalence, diff erential diagnosis and association with clinical and laboratory variables. Sao Paulo Medical Journal, vol. 132, no 3, pp. 140–146.
2. Weiss G. [et al.] (2010) Pathogenesis and treatment of anemia in Infl ammatory Bowel Disease. Haematologica, vol. 95, pp. 175–178.
3. Oustamanolakis P. [et al.] (2011) Diagnosing anemia in infl ammatory bowel disease: Beyond the established markers. Journal of Crohn’s and Colitis, vol. 5, no 5, pp. 381–391.
4. Gorgun YU., Karatish O., Portyanko A. (2007) Osobennosti korrektsii obmena zheleza pri hronicheskih vospalitel’nih zabolevaniyah kishechnika [Features of iron exchange correction in chronic infl ammatory bowel diseases]. Meditsinskie novosti, 11, pp. 82–84.
5. Murawska N. [et al.] (2016) Anemia of Chronic Disease and Iron Defi ciency Anemia in Infl ammatory Bowel Diseases: Pathophysiology, Diagnosis, and Treatment. Infl ammatory bowel diseases, vol. 22, no 5, pp. 1198–1208.
6. Basseri R. [et al.] (2013) Hepcidin is a key mediator of anemia of infl ammation in Crohn’s disease. Journal of Crohn’s and Colitis, vol. 7, no 8, pp. 286–291.
7. Armitage A. [et al.] (2011) Hepcidin regulation by innate immune and infectious stimuli. Blood, vol. 1, pp. 118–128.
8. Dignass A. [et al.] (2015) European Consensus on the Diagnosis and Management of Iron Defi ciency and Anaemia in Infl ammatory Bowel Diseases. Journal of Crohn’s and Colitis, vol. 1, pp. 1–12.
9. Oustamanolakis P. [et al.] (2011) Soluble transferrin receptor-ferritin index in the evaluation of anemia in infl ammatory bowel disease: a case-control study. Annals of Gastroenterology, vol. 24, no 2, pp. 108–114.
10. Abitbol V. [et al.] (2015) Diagnosis of Iron Defi ciency in Infl ammatory Bowel Disease by Transferrin Receptor-Ferritin Index. Medicine (Baltimore), vol. 94, no 26, pp. 98–105.
11. Kulnigg S. [et al.] (2008) A novel intravenous iron formulation for treatment of anemia in infl ammatory bowel disease: the ferric carboxymaltose [FERINJECT] randomized controlled trial. The American Journal of Gastroenterology, vol. 103, pp. 1182–1192.
12. Lee T. [et al.] (2012) Iron replacement therapy in infl ammatory bowel disease patients with iron defi ciency anemia: a systematic review and meta-analysis. Journal of Crohn’s and Colitis, vol. 6, pp. 267–275.
13. Kulnigg S. [et al.] (2006) Systematic review: managing anemia in Crohn’s disease. Alimentary Pharmacology & Therapeutics, vol. 24, pp. 1507–1523.
14. Weiss G. [et al.] (2005) Anemia of Chronic Disease. The New England Journal of Medicine, vol. 352, pp. 1011–1023.
15. WHO (1989) Preventing and controlling anemia through primary health care: a guide for health administrators and programme managers. Geneva, World Health Organization.
16. Wilson A. [et al.] (2004) Prevalence and outcomes of anemia in infl ammatory bowel disease: a systematic review of the literature. American Journal of Medicine, vol. 116, pp. 44–49.
17. Filmann N. [et al.] (2014) Prevalence of anemia in infl ammatory bowel diseases in European countries: a systematic review and individual patient data meta-analysis. Infl ammatory bowel diseases, vol. 20, no 12, pp. 936–945.
18. Koutroubakis I. [et al.] (2015) Persistent or recurrent anemia is associated with severe and disabling infl ammatory bowel disease. Clinical Gastroenterology and Hepatology, vol. 13, no 12, pp. 1760–1766.
19. Akhuemonkhan E. [et al.] (2017) Prevalence and screening for anemia in mild to moderate Crohn’s disease and ulcerative colitis in the United States, 2010–2014. BMJ Open Gastroenterology, vol. 4, no 1, pp. 1–8.
