Рецепт. 2021; 24: 515-522
Взаимосвязь нейровегетативных расстройств с компонентами метаболического синдрома у пациентов с ишемической болезнью сердца
https://doi.org/10.34883/PI.2021.24.4.008Аннотация
С целью установить взаимосвязь тревожно-депрессивных расстройств с компонентами метаболического синдрома у пациентов с ишемической болезнью сердца обследован 81 пациент с диагнозом ИБС – стабильная стенокардия напряжения I–III функционального класса: 1-я группа – 35 пациентов с ИБС, 2-я группа – 46 пациентов с ИБС в сочетании с метаболическим синдромом. С помощью суточного мониторирования ЭКГ, Сиэтловского опросника качества жизни, опросника SF-36, шкалы HADS исследованы клинические особенности пациентов с ишемической болезнью сердца во взаимосвязи с выраженностью тревожно-депрессивных расстройств. Установлено, что течение ИБС, коморбидной с метаболическим синдромом, ассоциировано с симпато-парасимпатическим дисбалансом, снижением качества жизни, более высокими суммарными уровнями тревоги и депрессии по шкале HADS, коррелирующими с такими компонентами метаболического синдрома, как абдоминальное ожирение, дислипидемия и гипергликемия.
Список литературы
1. Ipatov A.V., Moroz O.M., Khaniukova I.Ia., Mametiev A.O., Sanina N.A., Korobkin Yu.I., Molchanov R.M. (2020) Osnovni pokaznyky invalidnosti ta diialnosti medykosotsialnykh ekspertnykh komisii Ukrainy za 2019 rik: analityko-informatsiinyi dovidnyk [Main indices of disability and activity of medical-social expert commissions of Ukraine for 2019: analytical information handbook]. Dnipro: Aktsent PP. ISBN 978-966-921-223-8. (in Ukrainian)
2. Koshelia I.I., Skryp V.V. (2019). Epidemiolohiia ishemichnoi khvoroby sertsia ta infarktu miokarda v Zakarpatskii oblasti [Epidemiology of ischemic heart disease and myocardial infarction at the Zakarpattya region]. Ukraina. Zdorovia natsii, 3 (56), 51–54. doi: https://doi.org/10.24144/2077-6594.3.2019.191633
3. Rodynskyi O.H., Basysta K.I., Huz L.V. (2018) Neirokhimichni ta povedinkovi protsesy v herontohenezi za umov eksperementalnoi hiperhlikemii [Neurochemical and behavioral processes in gerontogenesis in conditions of experimental hyperglycemia]. Medychni perspektyvy, vol. 23, no 2, pp. 1–13.
4. Hsin-Pei Feng, Wu-Chien Chien, Wei-Tung Cheng, Chi-Hsiang Chung, Shu-Meng Cheng, Wen-Chii Tzeng (2016) Risk of anxiety and depressive disorders in patients with myocardial infarction. Medicine (Baltimore), Aug, 95 (34):e4464.
5. Marwijk H.W.J., Kooy K.G., Stehouwer C.D.A. (2015) Depression increases the onset of cardiovasculardisease over and above other determinants in older primary care patients, a cohort study. BMC Cardiovasc. Disord., vol. 15, issue 1, pp. 2–8.
6. Lankarani M.M., Assari S. (2016) 20-Year Cohort. Baseline Depressive Symptoms Predict Subsequent Heart Disease. Int. Cardiovasc. Res. J., vol. 10 (1), pp. 29–34.
7. Babenko A.Iu., Matveev H.A., Alekseenko T.Y., Derevytskyi Y.V., Kokyna M.A., Shliakhto E.V. (2019) Vzaymosviazy komponentov metabolycheskoho syndroma s urovnem hormonov, vovlechennikh v rehuliatsyiu metabolyzma zhyrovoi tkany. Arteryalnaia hypertenzyia (electronic journal), 25(6):639–652. Available at: https://doi.org/10.18705/1607-419X-2019-25-6-639-652.
8. Cosentino F., Grant P.J, Aboyans V. (2020) European Society of Cardiology guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD: The Task Force for diabetes, pre-diabetes, and cardiovascular diseases of the European Society of Cardiology (ESC) and the European Association for the Study of Diabetes (EASD). European Heart Journal, vol. 41, pp. 255–323.
9. Saklayen M.G. (2018) The Global Epidemic of the Metabolic Syndrome. Current Hypertension Reports, vol. 20 (2), p.12.
10. Petrova E.B., Shkrebneva E.I., Statkevich T.V., Kartun L.V., Mitkovskaya N.P. (2019) Abdominal obesity and postinfarction cardiosclerosis: cardiometabolic continuum in the development of chronic heart failure. Emergency cardiology and cardiovascular risks, vol. 3, pp. 507–512.
11. Yang C.D., Shen Y., Lu L. (2019) Insulin resistance and dysglycemia are associated with left ventricular remodeling after myocardial infarction in non-diabetic patients. et al. Cardiovascular Diabetology, vol. 18 (7). Available at: https://doi.org/10.1186/s12933-019-0904-3.
12. Bilchenko O.V., Lipakova K.Y., Rudenko T.A. (2020) Evaluation of heart failure with preserved ejection fraction in patients with coronary heart disease and type 2 diabetes mellitus. Problemy endokrynnoi patolohii, no 1, pp. 7–13.
Recipe. 2021; 24: 515-522
Relationship between Neurovegetative Disorders and Metabolic Syndrome Components in Patients with Coronary Heart Disease
https://doi.org/10.34883/PI.2021.24.4.008Abstract
In order to reveal the relationship of anxiety-depressive disorders with the components of metabolic syndrome in patients with ischemic heart disease, 81 patients with the diagnosis of ischemic heart disease were examined – stable exertional angina of the II-III functional class: group 1 – 35 patients with ischemic heart disease, group 2 – 46 patients with ischemic heart disease in combination with metabolic syndrome. Using daily ECG monitoring, the Seattle quality of life questionnaire, the SF-36 questionnaire, the HADS scale, the clinical features of patients with coronary heart disease in relation to the severity of anxiety-depressive disorders were investigated. It was found that the course of coronary artery disease, comorbid with metabolic syndrome, is associated with sympatheticparasympathetic imbalance, decreased quality of life, higher total levels of anxiety and depression on the HADS scale, correlating with such components of metabolic syndrome as abdominal obesity, dyslipidemia and hyperglycemia.
References
1. Ipatov A.V., Moroz O.M., Khaniukova I.Ia., Mametiev A.O., Sanina N.A., Korobkin Yu.I., Molchanov R.M. (2020) Osnovni pokaznyky invalidnosti ta diialnosti medykosotsialnykh ekspertnykh komisii Ukrainy za 2019 rik: analityko-informatsiinyi dovidnyk [Main indices of disability and activity of medical-social expert commissions of Ukraine for 2019: analytical information handbook]. Dnipro: Aktsent PP. ISBN 978-966-921-223-8. (in Ukrainian)
2. Koshelia I.I., Skryp V.V. (2019). Epidemiolohiia ishemichnoi khvoroby sertsia ta infarktu miokarda v Zakarpatskii oblasti [Epidemiology of ischemic heart disease and myocardial infarction at the Zakarpattya region]. Ukraina. Zdorovia natsii, 3 (56), 51–54. doi: https://doi.org/10.24144/2077-6594.3.2019.191633
3. Rodynskyi O.H., Basysta K.I., Huz L.V. (2018) Neirokhimichni ta povedinkovi protsesy v herontohenezi za umov eksperementalnoi hiperhlikemii [Neurochemical and behavioral processes in gerontogenesis in conditions of experimental hyperglycemia]. Medychni perspektyvy, vol. 23, no 2, pp. 1–13.
4. Hsin-Pei Feng, Wu-Chien Chien, Wei-Tung Cheng, Chi-Hsiang Chung, Shu-Meng Cheng, Wen-Chii Tzeng (2016) Risk of anxiety and depressive disorders in patients with myocardial infarction. Medicine (Baltimore), Aug, 95 (34):e4464.
5. Marwijk H.W.J., Kooy K.G., Stehouwer C.D.A. (2015) Depression increases the onset of cardiovasculardisease over and above other determinants in older primary care patients, a cohort study. BMC Cardiovasc. Disord., vol. 15, issue 1, pp. 2–8.
6. Lankarani M.M., Assari S. (2016) 20-Year Cohort. Baseline Depressive Symptoms Predict Subsequent Heart Disease. Int. Cardiovasc. Res. J., vol. 10 (1), pp. 29–34.
7. Babenko A.Iu., Matveev H.A., Alekseenko T.Y., Derevytskyi Y.V., Kokyna M.A., Shliakhto E.V. (2019) Vzaymosviazy komponentov metabolycheskoho syndroma s urovnem hormonov, vovlechennikh v rehuliatsyiu metabolyzma zhyrovoi tkany. Arteryalnaia hypertenzyia (electronic journal), 25(6):639–652. Available at: https://doi.org/10.18705/1607-419X-2019-25-6-639-652.
8. Cosentino F., Grant P.J, Aboyans V. (2020) European Society of Cardiology guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD: The Task Force for diabetes, pre-diabetes, and cardiovascular diseases of the European Society of Cardiology (ESC) and the European Association for the Study of Diabetes (EASD). European Heart Journal, vol. 41, pp. 255–323.
9. Saklayen M.G. (2018) The Global Epidemic of the Metabolic Syndrome. Current Hypertension Reports, vol. 20 (2), p.12.
10. Petrova E.B., Shkrebneva E.I., Statkevich T.V., Kartun L.V., Mitkovskaya N.P. (2019) Abdominal obesity and postinfarction cardiosclerosis: cardiometabolic continuum in the development of chronic heart failure. Emergency cardiology and cardiovascular risks, vol. 3, pp. 507–512.
11. Yang C.D., Shen Y., Lu L. (2019) Insulin resistance and dysglycemia are associated with left ventricular remodeling after myocardial infarction in non-diabetic patients. et al. Cardiovascular Diabetology, vol. 18 (7). Available at: https://doi.org/10.1186/s12933-019-0904-3.
12. Bilchenko O.V., Lipakova K.Y., Rudenko T.A. (2020) Evaluation of heart failure with preserved ejection fraction in patients with coronary heart disease and type 2 diabetes mellitus. Problemy endokrynnoi patolohii, no 1, pp. 7–13.
