Витамин D в комплексной терапии лекарственно-устойчивого туберкулеза

Статья в Elpub

Рецепт. 2018; : 179-187

Витамин D в комплексной терапии лекарственно-устойчивого туберкулеза

Кралько В. Я., Скрягина Е. М., Дюсьмикеева М. И., Скрягин А. Е.

Аннотация

В последнее время внимание многих исследователей привлечено к изучению витамина D, его влияния как на физиологические, так и на патологические процессы, происходящие в организме человека. Имеется ряд наблюдений о положительном воздействии витамина D на течение туберкулезного процесса, поэтому все чаще дискутируется вопрос о целесообразности его применения во фтизиатрической практике. У пациентов с лекарственно-устойчивым туберкулезом, которые на фоне противотуберкулезной химиотерапии принимали витамин D, была установлена положительная рентгенологическая и микробиологическая динамика, сопровождающаяся ростом и нормализацией абсолютного количества лимфоцитов периферической крови и субпопуляций Т-лимфоцитов, а также отмечалась конверсия культуры.

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Recipe. 2018; : 179-187

Vitamin D in the complex treatment of drug-resistant tuberculosis

Kralko V. ., Skrahina A. ., Dziusmikeyeva M. ., Skrahin A. .

Abstract

Recently, the attention of many researchers has been drawn to the study of vitamin D, its influence on both the physiological and pathological processes occurring in the human body. There are a number of observations on the positive effects of vitamin D on the course of the tuberculosis process, so the question of the appropriateness of its use in phthisiatric practice is increasingly being debated. In patients with drug-resistant tuberculosis who took vitamin D against antituberculous chemotherapy, positive X-ray and microbiological dynamics were established accompanied by an increase and normalization of the absolute number of peripheral blood lymphocytes and T-lymphocyte subpopulations, as well as a culture conversion.

References