Рецепт. 2020; : 313-336
Основные аспекты оказания фармацевтической помощи при реализации противогельминтных лекарственных средств
https://doi.org/10.34883/PI.2020.2.2.039Аннотация
По данным ВОЗ, гельминтозы занимают третье место в структуре инфекционных заболеваний. Рост заболеваемости обусловлен сбросом сточных вод в поверхностные водные объекты или непосредственно на землю, повышением миграции населения из стран с теплым климатом, увеличение численности домашних животных. В последнее время получена информация о развивающейся у гельминтов устойчивости к лекарственным средствам. В первой части статьи приводится понятие и классификация гельминтов, систематизирована информация о клинической картине наиболее часто встречающихся гельминтозов. Вторая часть посвящена 17 противогельминтным лекарственным средствам, зарегистрированным в Республике Беларусь. Приводится актуальная и систематизированная информация о показаниях и противопоказаниях по применению, побочных реакциях и лекарственных взаимодействиях с позиции причинно-следственных связей, опирающихся на фармакодинамические и фармакокинетические особенности лекарственных средств. Приведен алгоритм оказания фармацевтическим работником грамотной фармацевтической помощи (в т. ч. фармацевтического консультирования) посетителю, обратившемуся в аптеку с вопросом о приобретении противогельминтных средств.
Список литературы
1. Kryzhanovskiy S.A. (2007) Farmakologiya.: ucheb. dlya stud. sred.prof. uchebn. zavedeniy [Pharmacology: textbook for stud. of vocational schools]. Moscow: Publishing Center "Academy". (in Russian)
2. Bryukhanov V.M., Zverev Ya.F., Lampatov V.V., Zharikov A.Yu., Talalayeva O.S. (2014) Lektsii po farmakologii dlya vysshego meditsinskogo i farmatsevticheskogo obrazovaniya [Lectures in pharmacology for higher medical and pharmaceutical education]. Barnaul: Spectrum. (in Russian)
3. Alyautdin R.N., Preferanskiy N.G., Preferanskaya N.G. (2016) Farmakologiya: uchebnik [Pharmacology: textbook]. Moscow: GEOTAR-Media. (in Russian)
4. Gayevyy M.D., Petrov V.I., Gayevaya L.M., Davydov V.S. (2007) Farmakologiya s retsepturoy: uchebnik [Pharmacology with the formulation: textbook]. Moscow: ICC "Mart". (in Russian)
5. Beketov A.I. (1998) Kurs lektsiy po farmakologii (uchebnoye posobiye dlya otechestvennykh i inostrannykh studentov): V 2 ch. Chast’ 1 [Lecture course in pharmacology (study guide for Russian and foreign students): in 2 parts. Part 1]. Simferopol. (in Russian)
6. Vdovichenko V.P. (2014) Farmakologiya i farmakoterapiya: Posobiye dlya vrachey [Pharmacology and pharmacotherapy: A manual for doctors]. Minsk: Donarit. (in Russian)
7. Kharkevich D.A. (1993) Farmakologiya: uchebnik [Pharmacology: textbook]. Moscow: Medicine. (in Russian)
8. Kozlovskiy A.A. (2016) Gel’mintozy u detey Gomel’skoy oblasti [Helminthiasis in children of the Gomel region]. International reviews: clinical practice and health, no 1, pp. 68–83.
9. Fayzullina R.A., Samorodnova Ye.A., Dobrokvashina V.M. (2010) Gel’mintozy v detskom vozraste [Helminthiasis in childhood]. Practical medicine, no 3, pp. 31–36.
10. Shadrin O.G., Koval’chuk A.A., Dyukareva S.V., Fisun V.N. (2015) Prakticheskiye voprosy diagnostiki i lecheniya gel’mintozov u detey [Practicalissues of diagnosis and treatment of helminthiases in children]. Children’s Health, no 4, pp. 7–10.
11. Mochalova A.A. Yershova Ye.B. (2014) Vzglyad na problemu gel’mintozov i parazitov na sovremennom etape [A look at the problem of helminthiases and parasites at the present stage]. Actualnaya infektologіya, no 2, pp. 61–64.
12. Katzung B. (2018) Basic & Clinical Pharmacology, USA: McGraw-Hill Education.
13. Konorev M.R., Krapivko I.I., Rozhdestvenskiy D.A. (2013) Kurs lektsiy po farmakologii v 2-uh tomah: Tom 2 [Lecture course in pharmacology in 2 volumes: Volume 2]. Vitebsk: VGMU. (in Russian)
14. Reyestry UP Tsentr ekspertiz i ispytaniy v zdravookhranenii [Electronic resource]. Available at: http://www.rceth.by. Date of access: 13.09.2019.
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17. The DrugBank database [Electronic resource]. Available at: https://www.drugbank.ca Data of access: 14.09.2019.
18. Astaf’yev V.A. (2013) Osnovy farmakologii s retsepturoy: uchebnoye posobiye [Fundamentals of pharmacology with the formulation: a training manual]. Moscow: KNORUS. (in Russian)
19. Kukes V.G. (2004) Metabolizm lekarstvennykh sredstv: kliniko-farmakologicheskiye aspekty [Metabolism of drugs: clinical and pharmacological aspects]. Moscow: "Reafarm" Publishing House. (in Russian)
20. Bodnya E.I. (2016) Aktual’nyye podkhody v lechenii gel’mintozov [Actual approaches in the treatment of helminthiases]. Health of the child, no 3, pp. 111–116.
21. Krivopustov S.P., Shcherbinskaya E.N., Loginova I.A., Cherniy E.F., Pavlik E.V., Gerasimenko A.V. (2011) Gel’mintozy v klinicheskoy pediatrii: voprosy diagnostiki, terapii, profilaktiki [Helminthiasis in clinical pediatrics: issues of diagnosis, therapy, prevention]. Health of the child, no 4, pp. 71–75.
22. Yershova I.B., Mochalova A.A., Lokhmatova I.A., Manashova M.G., Petrenko O.V. (2015) Nespetsificheskiye proyavleniya gel’mintozov u detey [Nonspecific manifestations of helminthiases in children]. Health of the child, no 8, pp. 45–50.
23. WHO (2017) Guideline: preventive chemotherapy to control soil-transmitted helminth infections in at-risk population groups. WHO Library Cataloguing-in-Publication Data.
24. Pashinskaya E.S., Logishinets I A., Pobyarzhin V.V., Bekish V.E., Sobolevskaya I.S. (2013) Gel’mintozy pri beremennosti [Helminthiasis during pregnancy]. Vestnik VGMU, vol. 12, no 3, pp. 6–12.
25. Fedorchenko G.A. (2010) Gel’mintozy v praktike akushera-ginekologa [Helminthiasis in the practice of an obstetrician-gynecologist]. Medical aspects of women’s health, no 5–6, pp. 30–34.
26. Shekhtman M.M., Kozinova O.V. (2008) Gel’mintozy u beremennykh [Helminthiasis in pregnant women]. Gynecology, vol. 10, no 5, pp. 49–51.
27. Gerald G. Briggs, Roger K. Freeman, Sumner J. Yaffe (2015) Drugs in pregnancy and lactation: a reference guide to fetal and neonatal risk, USA: Wolters Kluwer.
28. Soboleva M.S., Amelina I.V. (2017) Mirovaya praktika osushchestvleniya professional’nykh funktsiy farmatsevticheskikh rabotnikov [World practice of professional functions of pharmaceutical workers]. Health and education in the XXI century, vol. 19, no 6, pp. 152–157.
29. El’yashevich E.G. (2015) Novyye funktsii provizora na sovremennom etape razvitiya farmatsii [New functions of a pharmacist at the present stage of pharmacy development]. Vestnik VGMU, vol. 14, no 1, pp. 6–11.
30. (2007) Ob utverzhdenii Nadlezhashchey aptechnoy praktiki: Postanovleniye Ministerstva zdravookhraneniya Respubliki Belarus’ ot 27 dekabrya 2006 g. № 120 (v redaktsii Postanovleniya Ministerstva zdravookhraneniya Respubliki Belarus’ ot 4 fevralya 2016 g. № 9) [On approval of Good pharmacy practice: The Decree of Ministry of Health of the Republic of Belarus of 27 December 2006 № 120 (in edition of the Decree of Ministry of Health of the Republic of Belarus of 4 February 2016 № 9)]. Natsional’nyy reyestr pravovykh aktov Respubliki Belarus’, 8/15774.
31. Mamykova O.I. (2013) Sravnitel’naya otsenka pobochnykh immunobiologicheskikh effektov antigel’mintnykh preparatov albendazola i mebendazola – proizvodnykh benzimidazola [Comparative evaluation of side immunobiological effects of anthelmintic drugs albendazole and mebendazole – benzimidazole derivatives]. Theory and practice of parasitic animal diseases, no 14, pp. 217–219.
32. Babayeva E.Yu., Chernysheva E.S., Nikolayeva S.A. (2015) Kompleksnoye ispol’zovaniye sinteticheskikh antigel’mintikov i rastitel’nykh preparatov pri glistnykh invaziyakh [The complex use of synthetic anthelmintics and herbal preparations for helminthic invasions]. Vestnik RUDN, series Medicine, no 2, pp. 93–99.
33. Abadi Amare Reda (2018) Probiotics for the Control of Helminth Zoonosis. Journal of Veterinary Medicine. doi: 10.1155/2018/4178986.
34. P’ng Loke, Yvonne A.L. Lim. (2015) Helminths and the microbiota: parts of the hygiene hypothesis. Parasite Immunol, no 37(6), pp. 314–323.
35. Dzhafarov M.Kh. (2013) Evolyutsiya khimioterapii gel’mintozov zhivotnykh i cheloveka [The evolution of chemotherapy for helminthiases in animals and humans]. Sel’skokhozyaystvennaya biologiya, no 4, pp. 26–44.
36. Doyle SR., Cotton JA. (2019) Genome-wide Approaches to Investigate Anthelmintic Resistance. Trends Parasitol, no 35(4), pp. 289–301.
37. Mutombo PN, Man NWY, Nejsum P, Ricketson R, Gordon CA, Robertson G, Clements ACA, Chacón-Fonseca N, Nissapatorn V, Webster JP, McLaws ML (2019) Diagnosis and drug resistance of human soil-transmitted helminth infections: A public health perspective. Adv Parasitol, no 104, pp. 247–326. doi: 10.1016/bs.apar.2019.02.004.
Recipe. 2020; : 313-336
The Main Aspects of Pharmaceutical Assistance in the Sale of Anthelmintic Medicines
https://doi.org/10.34883/PI.2020.2.2.039Abstract
References
1. Kryzhanovskiy S.A. (2007) Farmakologiya.: ucheb. dlya stud. sred.prof. uchebn. zavedeniy [Pharmacology: textbook for stud. of vocational schools]. Moscow: Publishing Center "Academy". (in Russian)
2. Bryukhanov V.M., Zverev Ya.F., Lampatov V.V., Zharikov A.Yu., Talalayeva O.S. (2014) Lektsii po farmakologii dlya vysshego meditsinskogo i farmatsevticheskogo obrazovaniya [Lectures in pharmacology for higher medical and pharmaceutical education]. Barnaul: Spectrum. (in Russian)
3. Alyautdin R.N., Preferanskiy N.G., Preferanskaya N.G. (2016) Farmakologiya: uchebnik [Pharmacology: textbook]. Moscow: GEOTAR-Media. (in Russian)
4. Gayevyy M.D., Petrov V.I., Gayevaya L.M., Davydov V.S. (2007) Farmakologiya s retsepturoy: uchebnik [Pharmacology with the formulation: textbook]. Moscow: ICC "Mart". (in Russian)
5. Beketov A.I. (1998) Kurs lektsiy po farmakologii (uchebnoye posobiye dlya otechestvennykh i inostrannykh studentov): V 2 ch. Chast’ 1 [Lecture course in pharmacology (study guide for Russian and foreign students): in 2 parts. Part 1]. Simferopol. (in Russian)
6. Vdovichenko V.P. (2014) Farmakologiya i farmakoterapiya: Posobiye dlya vrachey [Pharmacology and pharmacotherapy: A manual for doctors]. Minsk: Donarit. (in Russian)
7. Kharkevich D.A. (1993) Farmakologiya: uchebnik [Pharmacology: textbook]. Moscow: Medicine. (in Russian)
8. Kozlovskiy A.A. (2016) Gel’mintozy u detey Gomel’skoy oblasti [Helminthiasis in children of the Gomel region]. International reviews: clinical practice and health, no 1, pp. 68–83.
9. Fayzullina R.A., Samorodnova Ye.A., Dobrokvashina V.M. (2010) Gel’mintozy v detskom vozraste [Helminthiasis in childhood]. Practical medicine, no 3, pp. 31–36.
10. Shadrin O.G., Koval’chuk A.A., Dyukareva S.V., Fisun V.N. (2015) Prakticheskiye voprosy diagnostiki i lecheniya gel’mintozov u detey [Practicalissues of diagnosis and treatment of helminthiases in children]. Children’s Health, no 4, pp. 7–10.
11. Mochalova A.A. Yershova Ye.B. (2014) Vzglyad na problemu gel’mintozov i parazitov na sovremennom etape [A look at the problem of helminthiases and parasites at the present stage]. Actualnaya infektologіya, no 2, pp. 61–64.
12. Katzung B. (2018) Basic & Clinical Pharmacology, USA: McGraw-Hill Education.
13. Konorev M.R., Krapivko I.I., Rozhdestvenskiy D.A. (2013) Kurs lektsiy po farmakologii v 2-uh tomah: Tom 2 [Lecture course in pharmacology in 2 volumes: Volume 2]. Vitebsk: VGMU. (in Russian)
14. Reyestry UP Tsentr ekspertiz i ispytaniy v zdravookhranenii [Electronic resource]. Available at: http://www.rceth.by. Date of access: 13.09.2019.
15. The European Medicines Agency [Electronic resource]. Available at: http://www.ema.europa.eu. Date of access: 14.09.2019.
16. U.S. Food and Drug Administration [Electronic resource]. Available at: http://www.fda.gov. Date of access: 14.09.2019.
17. The DrugBank database [Electronic resource]. Available at: https://www.drugbank.ca Data of access: 14.09.2019.
18. Astaf’yev V.A. (2013) Osnovy farmakologii s retsepturoy: uchebnoye posobiye [Fundamentals of pharmacology with the formulation: a training manual]. Moscow: KNORUS. (in Russian)
19. Kukes V.G. (2004) Metabolizm lekarstvennykh sredstv: kliniko-farmakologicheskiye aspekty [Metabolism of drugs: clinical and pharmacological aspects]. Moscow: "Reafarm" Publishing House. (in Russian)
20. Bodnya E.I. (2016) Aktual’nyye podkhody v lechenii gel’mintozov [Actual approaches in the treatment of helminthiases]. Health of the child, no 3, pp. 111–116.
21. Krivopustov S.P., Shcherbinskaya E.N., Loginova I.A., Cherniy E.F., Pavlik E.V., Gerasimenko A.V. (2011) Gel’mintozy v klinicheskoy pediatrii: voprosy diagnostiki, terapii, profilaktiki [Helminthiasis in clinical pediatrics: issues of diagnosis, therapy, prevention]. Health of the child, no 4, pp. 71–75.
22. Yershova I.B., Mochalova A.A., Lokhmatova I.A., Manashova M.G., Petrenko O.V. (2015) Nespetsificheskiye proyavleniya gel’mintozov u detey [Nonspecific manifestations of helminthiases in children]. Health of the child, no 8, pp. 45–50.
23. WHO (2017) Guideline: preventive chemotherapy to control soil-transmitted helminth infections in at-risk population groups. WHO Library Cataloguing-in-Publication Data.
24. Pashinskaya E.S., Logishinets I A., Pobyarzhin V.V., Bekish V.E., Sobolevskaya I.S. (2013) Gel’mintozy pri beremennosti [Helminthiasis during pregnancy]. Vestnik VGMU, vol. 12, no 3, pp. 6–12.
25. Fedorchenko G.A. (2010) Gel’mintozy v praktike akushera-ginekologa [Helminthiasis in the practice of an obstetrician-gynecologist]. Medical aspects of women’s health, no 5–6, pp. 30–34.
26. Shekhtman M.M., Kozinova O.V. (2008) Gel’mintozy u beremennykh [Helminthiasis in pregnant women]. Gynecology, vol. 10, no 5, pp. 49–51.
27. Gerald G. Briggs, Roger K. Freeman, Sumner J. Yaffe (2015) Drugs in pregnancy and lactation: a reference guide to fetal and neonatal risk, USA: Wolters Kluwer.
28. Soboleva M.S., Amelina I.V. (2017) Mirovaya praktika osushchestvleniya professional’nykh funktsiy farmatsevticheskikh rabotnikov [World practice of professional functions of pharmaceutical workers]. Health and education in the XXI century, vol. 19, no 6, pp. 152–157.
29. El’yashevich E.G. (2015) Novyye funktsii provizora na sovremennom etape razvitiya farmatsii [New functions of a pharmacist at the present stage of pharmacy development]. Vestnik VGMU, vol. 14, no 1, pp. 6–11.
30. (2007) Ob utverzhdenii Nadlezhashchey aptechnoy praktiki: Postanovleniye Ministerstva zdravookhraneniya Respubliki Belarus’ ot 27 dekabrya 2006 g. № 120 (v redaktsii Postanovleniya Ministerstva zdravookhraneniya Respubliki Belarus’ ot 4 fevralya 2016 g. № 9) [On approval of Good pharmacy practice: The Decree of Ministry of Health of the Republic of Belarus of 27 December 2006 № 120 (in edition of the Decree of Ministry of Health of the Republic of Belarus of 4 February 2016 № 9)]. Natsional’nyy reyestr pravovykh aktov Respubliki Belarus’, 8/15774.
31. Mamykova O.I. (2013) Sravnitel’naya otsenka pobochnykh immunobiologicheskikh effektov antigel’mintnykh preparatov albendazola i mebendazola – proizvodnykh benzimidazola [Comparative evaluation of side immunobiological effects of anthelmintic drugs albendazole and mebendazole – benzimidazole derivatives]. Theory and practice of parasitic animal diseases, no 14, pp. 217–219.
32. Babayeva E.Yu., Chernysheva E.S., Nikolayeva S.A. (2015) Kompleksnoye ispol’zovaniye sinteticheskikh antigel’mintikov i rastitel’nykh preparatov pri glistnykh invaziyakh [The complex use of synthetic anthelmintics and herbal preparations for helminthic invasions]. Vestnik RUDN, series Medicine, no 2, pp. 93–99.
33. Abadi Amare Reda (2018) Probiotics for the Control of Helminth Zoonosis. Journal of Veterinary Medicine. doi: 10.1155/2018/4178986.
34. P’ng Loke, Yvonne A.L. Lim. (2015) Helminths and the microbiota: parts of the hygiene hypothesis. Parasite Immunol, no 37(6), pp. 314–323.
35. Dzhafarov M.Kh. (2013) Evolyutsiya khimioterapii gel’mintozov zhivotnykh i cheloveka [The evolution of chemotherapy for helminthiases in animals and humans]. Sel’skokhozyaystvennaya biologiya, no 4, pp. 26–44.
36. Doyle SR., Cotton JA. (2019) Genome-wide Approaches to Investigate Anthelmintic Resistance. Trends Parasitol, no 35(4), pp. 289–301.
37. Mutombo PN, Man NWY, Nejsum P, Ricketson R, Gordon CA, Robertson G, Clements ACA, Chacón-Fonseca N, Nissapatorn V, Webster JP, McLaws ML (2019) Diagnosis and drug resistance of human soil-transmitted helminth infections: A public health perspective. Adv Parasitol, no 104, pp. 247–326. doi: 10.1016/bs.apar.2019.02.004.
