Рецепт. 2018; : 84-90
Современная стратегия применения иммунотерапевтических препаратов в педиатрической практике
Аннотация
В статье представлены современные данные о применяемых иммунотерапевтических препаратах в педиатрии, разрешенных к применению в амбулаторной практике. Дана характеристика основных групп иммунотропных препаратов, их основных механизмов действия, рассмотрена тактика их назначения в педиатрии с учетом стадии инфекционного процесса и возможности безопасного применения у детей. Обсуждаются данные о механизмах действия пробиотических препаратов на иммунную систему и их назначения с целью иммунотерапии. Приводятся данные о новом синбиотике Флувир и о возможности его использования как для профилактики респираторной заболеваемости у детей, так и для безопасной коррекции иммунной системы после перенесенных заболеваний.
Список литературы
1. Novikov D., Novikov P. (2009) Clinical immunopathology. Moscow: Medical literature. (in Russian)
2. Yarilin A.A. (2010) Immunology. Moscow: GEOTAR-Media. (in Russian)
3. Robert R., Thomas F., William S. (2008) Clinical Immunology: principles and practice. 3rd Edition, Mosby.
4. Baranov A.A. (ed.) (2016) Federal clinical recommendations for the provision of medical care for children with acute respiratory viral infection. Moscow: Union of Pediatricians of Russia. (in Russian)
5. Ilyina S. (2014) Probiotics as immunomodulators and their place in the prevention of recurrent respiratory infections in children. Consilium Medicum. Pediatrics, vol. 03, pp. 28-33.
6. Lee Y.K., Mazmanian S.K. (2010) Has the microbiota played a critical role in the evolution of the adaptive immune system? Science, vol. 330, pp. 1768-1773.
7. Kornienko E., Netrebenko O. (2016) Probiotics: mechanisms of action and indications in accordance with international recommendations in pediatrics. Pediatrics, vol. 1, pp. 109-121.
8. Chopyak V., Potemkina G., Krill I., Belyanskaya L., Mazurak N., Lishchuk-Yakimovich Kh. (2015) Investigation of regulatory immune mechanisms in often ill children and the possibility of their correction. Sovremennaya pediatria, vol. 3, no 67, pp. 85-91. doi: 10.15574 / SP.2015.67.85
9. Fabrizio Pregliasco, Giovanni Bac Anselmi, Luigi Fonte, Francesco Giussani, Stefano Schieppati, Lidia Soletti. (2008) A New Chance of Preventing Winter Diseases by the Administration of Synbiotic Formulations. Journal of Clinical Gastroenterology, vol. 42, pp. S224-S233. doi: 10.1097/ MCG.0b013e31817e1c91
10. Guarner F., Khan A.G., Garisch J., Eliakim R., Gangl A., Thomson A., Krabshuis J., Lemair T., Kaufmann P., de Paula J.A. (2012) World Gastroenterology Organisation Global Guidelines:probiotics and prebiotics. J Clin Gastroenterol., vol. 46, pp. 468-481.
11. Johnston B.C., Goldenberg J.Z., Vandvik P.O., Sun X., Guyatt G.H. (2011) Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database Syst Rev, vol. 9, 11, pp. CD004827.
12. Foolad N., Brezinski E.A., Chase E.P., Armstrong A.W. (2013) Effect of nutrient supplementation on atopic dermatitis in children: a systematic review of probiotics, prebiotics, formula, and fatty acids. JAMA Dermatol, vol. 149, pp. 350-355.
13. Wickens K., Black P., Stanley T.V., Mitchell E., Barthow C., Fitzharris P. (2012) A protective effect of Lactobacillus rhamnosus HN001 against eczema in the first 2 years of life persists to age 4 years. Clin Exp Allergy, vol. 42, no 7, pp. 1071-1079.
14. Fiocchi (ed). (2015) Guidelines for Allergic Disease Prevention: Probiotics. Position article and guidelines. World Allergy Organization Journal, vol. 8, no 4. doi: 10.1186/s40413-015-0055-2
Recipe. 2018; : 84-90
Modern strategy of immunotherapeutic drugs use in pediatric practice
Abstract
References
1. Novikov D., Novikov P. (2009) Clinical immunopathology. Moscow: Medical literature. (in Russian)
2. Yarilin A.A. (2010) Immunology. Moscow: GEOTAR-Media. (in Russian)
3. Robert R., Thomas F., William S. (2008) Clinical Immunology: principles and practice. 3rd Edition, Mosby.
4. Baranov A.A. (ed.) (2016) Federal clinical recommendations for the provision of medical care for children with acute respiratory viral infection. Moscow: Union of Pediatricians of Russia. (in Russian)
5. Ilyina S. (2014) Probiotics as immunomodulators and their place in the prevention of recurrent respiratory infections in children. Consilium Medicum. Pediatrics, vol. 03, pp. 28-33.
6. Lee Y.K., Mazmanian S.K. (2010) Has the microbiota played a critical role in the evolution of the adaptive immune system? Science, vol. 330, pp. 1768-1773.
7. Kornienko E., Netrebenko O. (2016) Probiotics: mechanisms of action and indications in accordance with international recommendations in pediatrics. Pediatrics, vol. 1, pp. 109-121.
8. Chopyak V., Potemkina G., Krill I., Belyanskaya L., Mazurak N., Lishchuk-Yakimovich Kh. (2015) Investigation of regulatory immune mechanisms in often ill children and the possibility of their correction. Sovremennaya pediatria, vol. 3, no 67, pp. 85-91. doi: 10.15574 / SP.2015.67.85
9. Fabrizio Pregliasco, Giovanni Bac Anselmi, Luigi Fonte, Francesco Giussani, Stefano Schieppati, Lidia Soletti. (2008) A New Chance of Preventing Winter Diseases by the Administration of Synbiotic Formulations. Journal of Clinical Gastroenterology, vol. 42, pp. S224-S233. doi: 10.1097/ MCG.0b013e31817e1c91
10. Guarner F., Khan A.G., Garisch J., Eliakim R., Gangl A., Thomson A., Krabshuis J., Lemair T., Kaufmann P., de Paula J.A. (2012) World Gastroenterology Organisation Global Guidelines:probiotics and prebiotics. J Clin Gastroenterol., vol. 46, pp. 468-481.
11. Johnston B.C., Goldenberg J.Z., Vandvik P.O., Sun X., Guyatt G.H. (2011) Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database Syst Rev, vol. 9, 11, pp. CD004827.
12. Foolad N., Brezinski E.A., Chase E.P., Armstrong A.W. (2013) Effect of nutrient supplementation on atopic dermatitis in children: a systematic review of probiotics, prebiotics, formula, and fatty acids. JAMA Dermatol, vol. 149, pp. 350-355.
13. Wickens K., Black P., Stanley T.V., Mitchell E., Barthow C., Fitzharris P. (2012) A protective effect of Lactobacillus rhamnosus HN001 against eczema in the first 2 years of life persists to age 4 years. Clin Exp Allergy, vol. 42, no 7, pp. 1071-1079.
14. Fiocchi (ed). (2015) Guidelines for Allergic Disease Prevention: Probiotics. Position article and guidelines. World Allergy Organization Journal, vol. 8, no 4. doi: 10.1186/s40413-015-0055-2
