Альманах клинической медицины. 2014; : 108-111
СИЛДЕНАФИЛ И ХРОНИЧЕСКИЙ ПРОСТАТИТ
https://doi.org/10.18786/2072-0505-2014-34-108-111Аннотация
Предстательная железа анатомически и функционально тесно связана с уретрой, половыми железами и другими органами малого таза. Ее воспаление почти неизбежно сопровождается воспалением других мочеполовых органов, а также нарушениями половой функции, спермограммы, психоэмоциональной сферы, а у пожилых мужчин – доброкачественной гиперплазией предстательной железы. Представляется целесообразным применение ингибитора фосфодиэстеразы 5-го типа силденафила в комплексе реабилитационных мер после лечения хронического простатита, поскольку этот препарат способен устранять эректильную дисфункцию, тестикулярную недостаточность и депрессию, которые не исчезают на фоне стандартной терапии хронического простатита.
Список литературы
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16. Lefièvre L, De Lamirande E, Gagnon C. The cyclic GMP-specific phosphodiesterase inhibitor, sildenafil, stimulates human sperm motility and capacitation but not acrosome reaction. J Androl. 2000;21(6):929–37.
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18. (Borzhievskiy TsK, Fel’dman MYu. [Treatment of patients with chronic prostatitis at the Morshin resort]. Vestnik dermatologii. 1986;(1):64–7. Russian).
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20. (Fedorenko AE, Kolyadenko VG. [Dynamics of psychological and somatic components of anxiety in patients with genitourinary disorders]. Vestnik dermatologii. 1991;(10):47–9. Russian).
21. Egan KJ, Krieger JN. Psychological problems in chronic prostatitis patients with pain. Clin J Pain. 1994;10(3):218–26.
22. Моргунов ЛЮ. Силденафил: только ли лечение эректильной дисфункции? Эффективная фармакотерапия. 2013;(1):46–9. (Morgunov LYu. [Sildenafil: therapy of erectile dysfunction or more?]. Effektivnaya farmakoterapiya. 2013;(9):46–9. Russian).
23. Goldstein I, Lue TF, Padma-Nathan H, Rosen RC, Steers WD, Wicker PA. Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study Group. N Engl J Med. 1998;338(20):1397– 404.
24. Jarow JP, Burnett AL, Geringer AM. Clinical efficacy of sildenafil citrate based on etiology and response to prior treatment. J Urol. 1999;162(3 Pt 1):722–5.
25. Morales A, Gingell C, Collins M, Wicker PA, Osterloh IH. Clinical safety of oral sildenafil citrate (VIAGRA) in the treatment of erectile dysfunction. Int J Impot Res. 1998;10(2):69–73.
26. Padma-Nathan H, Eardley I, Kloner RA, Laties AM, Montorsi F. A 4-year update on the safety of sildenafil citrate (Viagra). Urology. 2002;60(2 Suppl 2):67–90.
27. McMahon CG. High dose sildenafil citrate as a salvage therapy for severe erectile dysfunction. Int J Impot Res. 2002;14(6):533–8.
Almanac of Clinical Medicine. 2014; : 108-111
SILDENAFIL AND CHRONIC PROSTATITIS
https://doi.org/10.18786/2072-0505-2014-34-108-111Abstract
Prostate stands in close anatomical and functional relations with urethra, genital glands and other pelvic organs. Inflammatory process in prostate is almost universally associated with inflammation in other genitourinary organs as well as sexual dysfunction, abnormal spermogram, psycho-emotional disorders and, in elderly men, with benign prostatic hyperplasia. Sildenafil (phosphodiesterase-5 inhibitor) is effective in the treatment of erectile dysfunction, testicular insufficiency and depression which may persist after the standard therapy of chronic prostatitis and is recommended as add-on to rehabilitation procedures after chronic prostatitis therapy.
References
1. Kaplun MI. Khronicheskii nespetsificheskii prostatit. Ufa: Bashkirskoe knizhnoe izdatel'stvo; 1984. 128 s. (Kaplun MI. Chronic nonspecific prostatitis. Ufa: Bashkirskoe knizhnoe izdatel’stvo; 1984. 128 r. Russian).
2. Molochkov VA, Il'in II. Khronicheskii uretrogennyi prostatit. M.: Meditsina; 2004. 288 s. (Molochkov VA, Il’in II. Chronic urethrogenic prostatitis. Moscow: Meditsina; 2004. 288 r. Russian).
3. May F. Zur Differential diagnose der chronischen prostatitis. Med Klinik. 1962;57:676–9.
4. Yunda IF. Prostatity. Kiev: Zdorov’ya; 1974. 192 s.
5. (Yunda IF. Prostatitis. Kiev: Zdorov’ya; 1974. 192 r. Russian).
6. Kamalov AA, Dorofeev SD, Efremov EA. Sovremennaya medikamentoznaya terapiya erektil'noi disfunktsii. Consilium Medicum. 2006;8(4):57–62.
7. (Kamalov AA, Dorofeev SD, Efremov EA. [Modern drug treatment for erectile dysfunction]. Consilium Medicum. 2006;8(4):57–62. Russian).
8. Capitanio U, Salonia A, Briganti A, Montorsi F. Silodosin in the management of lower urinary tract symptoms as a result of benign prostatic hyperplasia: who are the best candidates. Int J Clin Pract. 2013;67(6):544–51.
9. Kirby RS, Carson C 3rd, Dasgupta P. Daily phosphodiesterase type 5 inhibitor therapy: a new treatment option for prostatitis/ prostatodynia? BJU Int. 2014;113(5):694–5.
10. Doggrell SA. Comparison of clinical trials with sildenafil, vardenafil and tadalafil in erectile dysfunction. Expert Opin Pharmacother. 2005;6(1):75–84.
11. Kedia GT, Uckert S, Jonas U, Kuczyk MA, Burchardt M. The nitric oxide pathway in the human prostate: clinical implications in men with lower urinary tract symptoms. World J Urol. 2008;26(6):603–9.
12. Caremel R, Oger-Roussel S, Behr-Roussel D, Grise P, Giuliano F. Treatment of the lower urinary tract symptoms secondary to benign prostatic hyperplasia by phosphodiesterase type 5 inhibitors. Review article. Prog Urol. 2010;20(9):616–26.
13. Uckert S, Oelke M. Phosphodiesterase (PDE) inhibitors in the treatment of lower urinary tract dysfunction. Br J Clin Pharmacol. 2011;72(2):197–204.
14. Barabanov LG. Funktsional'noe sostoyanie gipofiza, polovykh zhelez i kory nadpochechnikov pri lechenii bol'nykh gonoreei, oslozhnennoi prostatitom. Vestnik dermatologii. 1989;(7):69–74.
15. (Barabanov LG. [Functional status of hypophysis, genital glands and adrenal cortex and its role in patients with gonorrhea and associated prostatitis]. Vestnik dermatologii. 1989;(7):69–74. Russian).
16. Lefièvre L, De Lamirande E, Gagnon C. The cyclic GMP-specific phosphodiesterase inhibitor, sildenafil, stimulates human sperm motility and capacitation but not acrosome reaction. J Androl. 2000;21(6):929–37.
17. Borzhievskii TsK, Fel'dman MYu. Lechenie bol'nykh khronicheskim prostatitom na kurorte Morshin. Vestnik dermatologii. 1986;(1):64–7.
18. (Borzhievskiy TsK, Fel’dman MYu. [Treatment of patients with chronic prostatitis at the Morshin resort]. Vestnik dermatologii. 1986;(1):64–7. Russian).
19. Fedorenko AE, Kolyadenko VG. Dinamika psikhologicheskoi i somaticheskoi sostavlyayushchei trevozhnosti pri porazheniyakh mochepolovykh organov u muzhchin. Vestnik dermatologii. 1991;(10):47–9.
20. (Fedorenko AE, Kolyadenko VG. [Dynamics of psychological and somatic components of anxiety in patients with genitourinary disorders]. Vestnik dermatologii. 1991;(10):47–9. Russian).
21. Egan KJ, Krieger JN. Psychological problems in chronic prostatitis patients with pain. Clin J Pain. 1994;10(3):218–26.
22. Morgunov LYu. Sildenafil: tol'ko li lechenie erektil'noi disfunktsii? Effektivnaya farmakoterapiya. 2013;(1):46–9. (Morgunov LYu. [Sildenafil: therapy of erectile dysfunction or more?]. Effektivnaya farmakoterapiya. 2013;(9):46–9. Russian).
23. Goldstein I, Lue TF, Padma-Nathan H, Rosen RC, Steers WD, Wicker PA. Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study Group. N Engl J Med. 1998;338(20):1397– 404.
24. Jarow JP, Burnett AL, Geringer AM. Clinical efficacy of sildenafil citrate based on etiology and response to prior treatment. J Urol. 1999;162(3 Pt 1):722–5.
25. Morales A, Gingell C, Collins M, Wicker PA, Osterloh IH. Clinical safety of oral sildenafil citrate (VIAGRA) in the treatment of erectile dysfunction. Int J Impot Res. 1998;10(2):69–73.
26. Padma-Nathan H, Eardley I, Kloner RA, Laties AM, Montorsi F. A 4-year update on the safety of sildenafil citrate (Viagra). Urology. 2002;60(2 Suppl 2):67–90.
27. McMahon CG. High dose sildenafil citrate as a salvage therapy for severe erectile dysfunction. Int J Impot Res. 2002;14(6):533–8.
