Альманах клинической медицины. 2014; 1: 61-65
БИОАНТИОКСИДАНТЫ (ЧАСТЬ 1)
https://doi.org/10.18786/2072-0505-2014-31-61-65Аннотация
В статье представлена синтетическая классификация известных биоантиоксидантов, описаны особенности их строения и функционирования. В данной части рассмотрены ферментативные и фенольные антиоксиданты, миметики ферментов.
Список литературы
1. Зенков Н.К., Ланкин В.З., Меньщикова Е.Б. Окислительный стресс: биохимический и патофизиологический аспекты. М.: МАИК «Наука/Интерпериодика»; 2001. [Zenkov N.K., Lan-kin V.Z., Men'shchikova E.B. Oxidative stress: biochemical and pathophysiological aspects. Moscow: MAIK «Nauka/Interperiodika»; 2001 (in Russian)].
2. Зенков Н.К., Кандалинцева Н.В., Ланкин В.З., Меньщикова Е.Б., Просенко А.Е. Фенольные биоантиоксиданты. Новосибирск: СО РАМН; 2003. [Zenkov N.K., Kandalintseva N.V., Lankin V.Z., Men’shchikova E.B., Prosenko A.E. Phenolic bioantioxidants. Novosibirsk: SO RAMN; 2003 (in Russian)].
3. Костюк В.А. , Потапович А.И. Биорадикалы и биоантиоксиданты. Минск: Издательство БГУ; 2004. [Kostyuk V.A., Potapovich A.I. Bioradicals and bioantioxidants. Minsk: Izdate’lstvo BGU; 2004 (in Russian)].
4. Барабой В.А. Биоантиоксиданты. M.: Книга плюс; 2006. [Baraboy V.A. Bioantioxidants. Moscow: Kniga plyus; 2006 (in Russian)].
5. Меньщикова Е.Б., Ланкин В.З., Зенков Н.К., Бондарь И.А., Круговых Н.Ф., Труфакин В.А. Окислительный стресс. Прооксиданты и антиоксиданты. M.: Слово; 2006. [Men’shchikova E.B., Lankin V.Z., Zenkov N.K., Bondar’ I.A., Krugovykh N.F., Trufakin V.A. Oxidative stress. Pro-oxidants and antioxidants. Moscow: Slovo; 2006 (in Russian)].
6. Агабейли Р.А. Биоантиоксиданты: роль в генетической устойчивости и охране биоразнообразия. Баку: Элм; 2008. [Agabeyli R.A. Bioantioxidants: role in genetic stability and preservation of biovariety. Baku: Elm; 2008 (in Russian)].
7. Попова Н.Р., Гудков С.В., Брусков В.И. Природные пуриновые соединения как радиозащитные средства. Радиационная биология. Радиоэкология 2014;54(1):38-49. [Popova N.R., Gudkov S.V., Bruskov V.I. Natural purine compounds as radioprotective agents. Radiatsionnaya biologiya. Radioekologiya 2014;54(1): 38-49 (in Russian)].
8. Chernikov A.V., Bruskov V.I., Gudkov S.V. Heat-induced formation of nitrogen oxides in water. J Biol Phys 2013;39(4):687-99.
9. Bruskov V.I., Karp O.E., Garmash S.A., Shtarkman I.N., Chernikov A.V., Gudkov S.V. Prolongation of oxidative stress by long-lived reactive protein species induced by X-ray radiation and their genotoxic action. Free Radic Res 2012;46(10):1280-90.
10. Гудков С.В., Карп О.Э., Гармаш С.А., Иванов В.Е., Черников А.В., Манохин А.А., Асташев М.Е., Ягужинский Л.С., Брусков В.И. Образование активных форм кислорода в воде под воздействием видимого и инфракрасного излучения в полосах поглощения молекулярного кислорода. Биофизика 2012;57(1):5-13. [Gudkov S.V., Karp O.E., Garmash S.A., Ivanov V.E., Chernikov A.V., Manokhin A.A., Astashev M.E., Yaguzhinskiy L.S., Bruskov V.I. Production of reactive oxygen forms in water under the influence of visual and infra-red radiation in lines of the molecular oxygen absorption. Biofizika 2012;57(1):5-13 (in Russian)].
11. Gudkov S.V., Bruskov V.I., Astashev M.E., Chernikov A.V., Yaguzhinsky L.S., Zakharov S.D. Oxygen-dependent autooscillations of water luminescence triggered by the 1264 nm radiation. J Phys Chem B 2011;115(23):7693-8.
12. Гудкова О.Ю., Гудков С.В., Гапеев А.Б., Брусков В.И., Рубаник А.В., Чемерис Н.К. Исследование механизмов образования активных форм кислорода в водных растворах под действием импульсного электромагнитного излучения крайне высоких частот с большой пиковой мощностью. Биофизика 2005; 50(5):773-9. [Gudkova O.Yu., Gudkov S.V., Gapeev A.B., Bruskov V.I., Rubanik A.V., Chemeris N.K. Studying the mechanisms of the reactive oxygen forms production in aqueous solutions under the influence of impulse electromagnetic radiation of extremely high frequencies with large peak power. Biofizika 2005;50(5):773-9 (in Russian)].
13. McCord J.M., Fridovich I. Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J Biol Chem 1969; 244(22):6049-55.
14. Bafana A., Dutt S., Kumar S., Ahuja P.S. Superoxide dismutase: an industrial perspective. Crit Rev Biotechnol 2011;31(1):65-76.
15. Поберезкина Н.Е., Лосинская Л.Ф. Биологическая роль супероксиддисмутазы. Украинский биохимический журнал 1989; 61(2):14-27. [Poberezkina N.E., Losinskaya L.F. Biological role of super-peroxide-dismutase. Ukrainskiy biokhimicheskiy zhurnal 1989;61(2):14-27 (in Russian)].
16. Никольская Е.А., Синявская О.И. Каталазы, выделяемые микроорганизмами. Микробиология 1984;46(4):83-93. [Nikolskaya E.A., Sinyavskaya O.I. Catalases excreted by microorganisms. Mikrobiologiya 1984;46(4):83-93 (in Russian)].
17. Fernandez V., Videla L.A. Biochemical aspects of cellular antioxidant systems. Biol Res 1996;29(2):177-82.
18. Mills G.C. Hemoglobin catabolism. I. Glutathione peroxidase, an erythrocyte enzyme which protects hemoglobin from oxidative breakdown. J Biol Chem 1957;229(1):189-97.
19. Логинов А.С., Матюшин Б.Н., Ткачев В.Д., Якимчук Г.Н. Новый подход к диагностике холестаза по активности медьсодержащих ферментов. Терапевтический архив 1993;(2):34-6. [Loginov A.S., Matyushin B.N., Tkachev V.D., Yakimchuk G.N. A new approach to cholestasis diagnosis based on the activity of the copper-containing enzymes. Terapevticheskiy arkhiv 1993;(2): 34-6 (in Russian)].
20. Pearson W.R. Phylogenies of glutathione transferase families. Methods Enzymol 2005;401:186-204.
21. Гудков С.В., Брусков В.И. Гуанозин и инозин (рибоксин). Антиоксидантные и радиозащитные свойства. Saarbrücken: Lambert Academic Publishing; 2011. [Gudkov S.V., Bruskov V.I. Guanosine and inosine (riboxin). Antioxidant and radioprotective properties. Saarbrücken: Lambert Academic Publishing; 2011 (in Russian)].
22. Рогинский В.А. Фенольные антиоксиданты: реакционная способность и эффективность. М.: Наука; 1988. [Roginskiy V.A. Phenolic antioxidants: reactive capacity and effectiveness. Moscow: Nauka; 1988 (in Russian)].
23. Гудков С.В. Механизмы образования активных форм кислорода под влиянием физических факторов и их генотоксическое действие [диссертация]. Пущино: ИТЭБ РАН; 2012. [Gudkov S.V. The mechanisms of the reactive oxygen species production under the influence of physical factors and their genotoxic activity [dissertation]. Pushchino: ITEB RAS; 2012 (in Russian)].
24. Кретович В.Л. Биохимия растений. М.: Высшая школа; 1980. [Kretovich V.L. Plant biochemistry. Moscow: Vysshaya shkola; 1980 (in Russian)].
25. Terao J., Mukai R. Prenylation modulates the bioavailability and bioaccumulation of dietary flavonoids. Arch Biochem Biophys 2014;pii:S0003-9861(14)00125-8. [Epub ahead of print].
26. Kumar S., Pandey A.K. Chemistry and biological activities of flavonoids: an overview. ScientificWorldJournal 2013;162750.
27. Pekmezci D. Vitamin E and immunity. Vitam Horm 2011;86: 179-215.
28. Evans H., Emerson О., Emerson G. The isolation from wheat germ of an alcohol α-tocopherol. J Biol Chem 1936;113:319-25.
29. Jiang Q. Natural forms of vitamin E: metabolism, antioxidant, and anti-inflammatory activities and their role in disease prevention and therapy. Free Radic Biol Med 2014;72C:76-90. [Epub ahead of print].
30. Rahman I. Antioxidant therapeutic advances in COPD. Ther Adv Respir Dis 2008;2(6):351-74.
31. Salvemini D., Wang Z.Q., Zweier J.L., Samouilov A., Macarthur H., Misko T.P., Currie M.G., Cuzzocrea S., Sikorski J.A., Riley D.P. A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats. Science 1999;286(5438):304-6.
32. Muscoli C., Sacco I., Alecce W., Palma E., Nisticò R., Costa N., Clementi F., Rotiroti D., Romeo F., Salvemini D., Mehta J.L. The protective effect of superoxide dismutase mimetic M40401 on balloon injury-related neointima formation: role of the lectin-like oxidized low-density lipoprotein receptor-1. J Pharmacol Exp Ther 2004;311:44-50.
33. Thompson J.S., Chu Y., Glass J., Tapp A.A., Brown S.A. The manganese superoxide dismutase mimetic, M40403, protects adult mice from lethal total body irradiation. Free Radic Res 2010;44(5):529-40.
34. Chatterjee P.K., Patel N.S., Kvale E.O., Brown P.A., Stewart K.N., Mota-Filipe H., Sharpe M.A., Di Paola R., Cuzzocrea S., Thiemermann C. EUK-134 reduces renal dysfunction and injury caused by oxidative and nitrosative stress of the kidney. Am J Nephrol 2004;24(2):165-77.
35. Sharpe M.A., Ollosson R., Stewart V.C., Clark J.B. Oxidation of nitric oxide by oxomanganese-salen complexes: a new mechanism for cellular protection by superoxide dismutase/catalase mimetics. Biochem J 2002;366(Pt 1):97-107.
Almanac of Clinical Medicine. 2014; 1: 61-65
THE BIOANTIOXIDANTS (PART 1)
https://doi.org/10.18786/2072-0505-2014-31-61-65Abstract
Based on the analysis of the latest scientific data, the paper suggests synthetic classification of known bioantioxidants, peculiarities of their structure and functioning. Enzymatic, phenolic antioxidants, and enzyme mimetics are described in this part of the
review.
References
1. Zenkov N.K., Lankin V.Z., Men'shchikova E.B. Okislitel'nyi stress: biokhimicheskii i patofiziologicheskii aspekty. M.: MAIK «Nauka/Interperiodika»; 2001. [Zenkov N.K., Lan-kin V.Z., Men'shchikova E.B. Oxidative stress: biochemical and pathophysiological aspects. Moscow: MAIK «Nauka/Interperiodika»; 2001 (in Russian)].
2. Zenkov N.K., Kandalintseva N.V., Lankin V.Z., Men'shchikova E.B., Prosenko A.E. Fenol'nye bioantioksidanty. Novosibirsk: SO RAMN; 2003. [Zenkov N.K., Kandalintseva N.V., Lankin V.Z., Men’shchikova E.B., Prosenko A.E. Phenolic bioantioxidants. Novosibirsk: SO RAMN; 2003 (in Russian)].
3. Kostyuk V.A. , Potapovich A.I. Bioradikaly i bioantioksidanty. Minsk: Izdatel'stvo BGU; 2004. [Kostyuk V.A., Potapovich A.I. Bioradicals and bioantioxidants. Minsk: Izdate’lstvo BGU; 2004 (in Russian)].
4. Baraboi V.A. Bioantioksidanty. M.: Kniga plyus; 2006. [Baraboy V.A. Bioantioxidants. Moscow: Kniga plyus; 2006 (in Russian)].
5. Men'shchikova E.B., Lankin V.Z., Zenkov N.K., Bondar' I.A., Krugovykh N.F., Trufakin V.A. Okislitel'nyi stress. Prooksidanty i antioksidanty. M.: Slovo; 2006. [Men’shchikova E.B., Lankin V.Z., Zenkov N.K., Bondar’ I.A., Krugovykh N.F., Trufakin V.A. Oxidative stress. Pro-oxidants and antioxidants. Moscow: Slovo; 2006 (in Russian)].
6. Agabeili R.A. Bioantioksidanty: rol' v geneticheskoi ustoichivosti i okhrane bioraznoobraziya. Baku: Elm; 2008. [Agabeyli R.A. Bioantioxidants: role in genetic stability and preservation of biovariety. Baku: Elm; 2008 (in Russian)].
7. Popova N.R., Gudkov S.V., Bruskov V.I. Prirodnye purinovye soedineniya kak radiozashchitnye sredstva. Radiatsionnaya biologiya. Radioekologiya 2014;54(1):38-49. [Popova N.R., Gudkov S.V., Bruskov V.I. Natural purine compounds as radioprotective agents. Radiatsionnaya biologiya. Radioekologiya 2014;54(1): 38-49 (in Russian)].
8. Chernikov A.V., Bruskov V.I., Gudkov S.V. Heat-induced formation of nitrogen oxides in water. J Biol Phys 2013;39(4):687-99.
9. Bruskov V.I., Karp O.E., Garmash S.A., Shtarkman I.N., Chernikov A.V., Gudkov S.V. Prolongation of oxidative stress by long-lived reactive protein species induced by X-ray radiation and their genotoxic action. Free Radic Res 2012;46(10):1280-90.
10. Gudkov S.V., Karp O.E., Garmash S.A., Ivanov V.E., Chernikov A.V., Manokhin A.A., Astashev M.E., Yaguzhinskii L.S., Bruskov V.I. Obrazovanie aktivnykh form kisloroda v vode pod vozdeistviem vidimogo i infrakrasnogo izlucheniya v polosakh pogloshcheniya molekulyarnogo kisloroda. Biofizika 2012;57(1):5-13. [Gudkov S.V., Karp O.E., Garmash S.A., Ivanov V.E., Chernikov A.V., Manokhin A.A., Astashev M.E., Yaguzhinskiy L.S., Bruskov V.I. Production of reactive oxygen forms in water under the influence of visual and infra-red radiation in lines of the molecular oxygen absorption. Biofizika 2012;57(1):5-13 (in Russian)].
11. Gudkov S.V., Bruskov V.I., Astashev M.E., Chernikov A.V., Yaguzhinsky L.S., Zakharov S.D. Oxygen-dependent autooscillations of water luminescence triggered by the 1264 nm radiation. J Phys Chem B 2011;115(23):7693-8.
12. Gudkova O.Yu., Gudkov S.V., Gapeev A.B., Bruskov V.I., Rubanik A.V., Chemeris N.K. Issledovanie mekhanizmov obrazovaniya aktivnykh form kisloroda v vodnykh rastvorakh pod deistviem impul'snogo elektromagnitnogo izlucheniya kraine vysokikh chastot s bol'shoi pikovoi moshchnost'yu. Biofizika 2005; 50(5):773-9. [Gudkova O.Yu., Gudkov S.V., Gapeev A.B., Bruskov V.I., Rubanik A.V., Chemeris N.K. Studying the mechanisms of the reactive oxygen forms production in aqueous solutions under the influence of impulse electromagnetic radiation of extremely high frequencies with large peak power. Biofizika 2005;50(5):773-9 (in Russian)].
13. McCord J.M., Fridovich I. Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J Biol Chem 1969; 244(22):6049-55.
14. Bafana A., Dutt S., Kumar S., Ahuja P.S. Superoxide dismutase: an industrial perspective. Crit Rev Biotechnol 2011;31(1):65-76.
15. Poberezkina N.E., Losinskaya L.F. Biologicheskaya rol' superoksiddismutazy. Ukrainskii biokhimicheskii zhurnal 1989; 61(2):14-27. [Poberezkina N.E., Losinskaya L.F. Biological role of super-peroxide-dismutase. Ukrainskiy biokhimicheskiy zhurnal 1989;61(2):14-27 (in Russian)].
16. Nikol'skaya E.A., Sinyavskaya O.I. Katalazy, vydelyaemye mikroorganizmami. Mikrobiologiya 1984;46(4):83-93. [Nikolskaya E.A., Sinyavskaya O.I. Catalases excreted by microorganisms. Mikrobiologiya 1984;46(4):83-93 (in Russian)].
17. Fernandez V., Videla L.A. Biochemical aspects of cellular antioxidant systems. Biol Res 1996;29(2):177-82.
18. Mills G.C. Hemoglobin catabolism. I. Glutathione peroxidase, an erythrocyte enzyme which protects hemoglobin from oxidative breakdown. J Biol Chem 1957;229(1):189-97.
19. Loginov A.S., Matyushin B.N., Tkachev V.D., Yakimchuk G.N. Novyi podkhod k diagnostike kholestaza po aktivnosti med'soderzhashchikh fermentov. Terapevticheskii arkhiv 1993;(2):34-6. [Loginov A.S., Matyushin B.N., Tkachev V.D., Yakimchuk G.N. A new approach to cholestasis diagnosis based on the activity of the copper-containing enzymes. Terapevticheskiy arkhiv 1993;(2): 34-6 (in Russian)].
20. Pearson W.R. Phylogenies of glutathione transferase families. Methods Enzymol 2005;401:186-204.
21. Gudkov S.V., Bruskov V.I. Guanozin i inozin (riboksin). Antioksidantnye i radiozashchitnye svoistva. Saarbrücken: Lambert Academic Publishing; 2011. [Gudkov S.V., Bruskov V.I. Guanosine and inosine (riboxin). Antioxidant and radioprotective properties. Saarbrücken: Lambert Academic Publishing; 2011 (in Russian)].
22. Roginskii V.A. Fenol'nye antioksidanty: reaktsionnaya sposobnost' i effektivnost'. M.: Nauka; 1988. [Roginskiy V.A. Phenolic antioxidants: reactive capacity and effectiveness. Moscow: Nauka; 1988 (in Russian)].
23. Gudkov S.V. Mekhanizmy obrazovaniya aktivnykh form kisloroda pod vliyaniem fizicheskikh faktorov i ikh genotoksicheskoe deistvie [dissertatsiya]. Pushchino: ITEB RAN; 2012. [Gudkov S.V. The mechanisms of the reactive oxygen species production under the influence of physical factors and their genotoxic activity [dissertation]. Pushchino: ITEB RAS; 2012 (in Russian)].
24. Kretovich V.L. Biokhimiya rastenii. M.: Vysshaya shkola; 1980. [Kretovich V.L. Plant biochemistry. Moscow: Vysshaya shkola; 1980 (in Russian)].
25. Terao J., Mukai R. Prenylation modulates the bioavailability and bioaccumulation of dietary flavonoids. Arch Biochem Biophys 2014;pii:S0003-9861(14)00125-8. [Epub ahead of print].
26. Kumar S., Pandey A.K. Chemistry and biological activities of flavonoids: an overview. ScientificWorldJournal 2013;162750.
27. Pekmezci D. Vitamin E and immunity. Vitam Horm 2011;86: 179-215.
28. Evans H., Emerson O., Emerson G. The isolation from wheat germ of an alcohol α-tocopherol. J Biol Chem 1936;113:319-25.
29. Jiang Q. Natural forms of vitamin E: metabolism, antioxidant, and anti-inflammatory activities and their role in disease prevention and therapy. Free Radic Biol Med 2014;72C:76-90. [Epub ahead of print].
30. Rahman I. Antioxidant therapeutic advances in COPD. Ther Adv Respir Dis 2008;2(6):351-74.
31. Salvemini D., Wang Z.Q., Zweier J.L., Samouilov A., Macarthur H., Misko T.P., Currie M.G., Cuzzocrea S., Sikorski J.A., Riley D.P. A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats. Science 1999;286(5438):304-6.
32. Muscoli C., Sacco I., Alecce W., Palma E., Nisticò R., Costa N., Clementi F., Rotiroti D., Romeo F., Salvemini D., Mehta J.L. The protective effect of superoxide dismutase mimetic M40401 on balloon injury-related neointima formation: role of the lectin-like oxidized low-density lipoprotein receptor-1. J Pharmacol Exp Ther 2004;311:44-50.
33. Thompson J.S., Chu Y., Glass J., Tapp A.A., Brown S.A. The manganese superoxide dismutase mimetic, M40403, protects adult mice from lethal total body irradiation. Free Radic Res 2010;44(5):529-40.
34. Chatterjee P.K., Patel N.S., Kvale E.O., Brown P.A., Stewart K.N., Mota-Filipe H., Sharpe M.A., Di Paola R., Cuzzocrea S., Thiemermann C. EUK-134 reduces renal dysfunction and injury caused by oxidative and nitrosative stress of the kidney. Am J Nephrol 2004;24(2):165-77.
35. Sharpe M.A., Ollosson R., Stewart V.C., Clark J.B. Oxidation of nitric oxide by oxomanganese-salen complexes: a new mechanism for cellular protection by superoxide dismutase/catalase mimetics. Biochem J 2002;366(Pt 1):97-107.
