Онкопедиатрия. 2015; 2: 404-408
Мультифокальная остеосаркома: описание клинического случая
https://doi.org/10.15690/onco.v2.i4.1467Аннотация
В статье приводится редкий клинический случай мультифокальной синхронной остеосаркомы у пациента в возрасте 10 лет с поражением бедренных и правой плечевой костей, выявленный в одной из клиник Израиля в 2014 г. Пациенту было проведено комбинированное лечение, включавшее эндопротезирование пораженных участков. На момент написания статьи пациент жив без признаков проявления заболевания и может самостоятельно передвигаться без помощи костылей.
Список литературы
1. WHO Classification of Tumours of Soft Tissue and Bone (Vol. 5). Ed. by Fletcher CDM, Bridge JA, Hogendoorn P, Mertens F. 2013 (4th ed). 427 p.
2. Ritter J, Bielack SS. Osteosarcoma. Annals of Oncology. 2010;21:320–325.
3. Сенжапова ЭР. Возможности применения таргетной терапии при лечении остеосаркомы у детей и подростков (литературный обзор). Саркомы костей, мягких тканей и опухоли кожи. 2014;2:34–44.
4. Perker-Fruhauf U.M., Friesenbichler J., Rabitsch K., Liegl-Atzwanger B., Bauernhofer T., Windhager R., Leithner A. Three Metachronous Osteosarcomas within 22 years without Pulmonary Metastases: A Case Report and Review of the Literature. Case Repoorts in Orthopedics. 2013. Article ID 197287.
5. Maheshwari AV, Jelinek JS, Seibel NL, Meloni-Ehrig AM, Kumar D, Henshaw RM. Bilateral synchronous tibial periostal osteosarcoma with familia incidence. Skeletal Radiol. 2012;41:1005– 1009.
6. Kunze B., Burkle S., Kluba T. Multifocal osteosarcoma in childhood. Musculoskelet Surg. 2009;93:27–31.
7. Bacci G, Fabbri N, Balladelli A. et al. Treatment and prognosis for synchronous multifocal osteosarcoma in 42 patients. J Bone Joint Surg Br. 2006;88(8):1071–1075.
8. Brandal P, Bjerkehagen B, Bruland ØS, Skjeldal S, Bogsrud TV, Hall KS. Synchronous and metachronous skeletal osteosarcomas: the Norwegian Radium Hospital experience. Acta Oncologica. 2009;48(8):1165–1172.
9. Corradi D., Wenger D.E., Bertoni F., Bacchini P., Bosio S., Goldoni M. et al. Multicentric Osteosarcoma. Clinicopathologic and Radiographic Study of 56 Cases. Am J Clin Pathol. 2011;136:799–807.
10. Currall VA, Dixon JH. Synchronous Multifocal Osteosarcoma: Case Report and Literature Review. Sarcoma. 2006; Article ID 53901. Р. 1–3.
Oncopediatrics. 2015; 2: 404-408
Multifocal Osteosarcoma: A Case Report
https://doi.org/10.15690/onco.v2.i4.1467Abstract
The article describes a unique clinical case of multifocal synchronous osteosarcoma patient 10 years old with the defeat of the right femur and humerus identified in a clinic in Israel in 2014. The patient was conducted a combined treatment including arthroplasty. At the time of this writing, the patient is alive without evidence of disease manifestations and can independently move without crutches.
References
1. WHO Classification of Tumours of Soft Tissue and Bone (Vol. 5). Ed. by Fletcher CDM, Bridge JA, Hogendoorn P, Mertens F. 2013 (4th ed). 427 p.
2. Ritter J, Bielack SS. Osteosarcoma. Annals of Oncology. 2010;21:320–325.
3. Senzhapova ER. Vozmozhnosti primeneniya targetnoi terapii pri lechenii osteosarkomy u detei i podrostkov (literaturnyi obzor). Sarkomy kostei, myagkikh tkanei i opukholi kozhi. 2014;2:34–44.
4. Perker-Fruhauf U.M., Friesenbichler J., Rabitsch K., Liegl-Atzwanger B., Bauernhofer T., Windhager R., Leithner A. Three Metachronous Osteosarcomas within 22 years without Pulmonary Metastases: A Case Report and Review of the Literature. Case Repoorts in Orthopedics. 2013. Article ID 197287.
5. Maheshwari AV, Jelinek JS, Seibel NL, Meloni-Ehrig AM, Kumar D, Henshaw RM. Bilateral synchronous tibial periostal osteosarcoma with familia incidence. Skeletal Radiol. 2012;41:1005– 1009.
6. Kunze B., Burkle S., Kluba T. Multifocal osteosarcoma in childhood. Musculoskelet Surg. 2009;93:27–31.
7. Bacci G, Fabbri N, Balladelli A. et al. Treatment and prognosis for synchronous multifocal osteosarcoma in 42 patients. J Bone Joint Surg Br. 2006;88(8):1071–1075.
8. Brandal P, Bjerkehagen B, Bruland ØS, Skjeldal S, Bogsrud TV, Hall KS. Synchronous and metachronous skeletal osteosarcomas: the Norwegian Radium Hospital experience. Acta Oncologica. 2009;48(8):1165–1172.
9. Corradi D., Wenger D.E., Bertoni F., Bacchini P., Bosio S., Goldoni M. et al. Multicentric Osteosarcoma. Clinicopathologic and Radiographic Study of 56 Cases. Am J Clin Pathol. 2011;136:799–807.
10. Currall VA, Dixon JH. Synchronous Multifocal Osteosarcoma: Case Report and Literature Review. Sarcoma. 2006; Article ID 53901. R. 1–3.
