Опухоли головы и шеи. 2015; 5: 13-15
Коррекция нутритивной недостаточности у больных плоскоклеточным раком орофарингеальной зоны
https://doi.org/10.17650/2222-1468-2015-5-3-13-15Аннотация
Лечение плоскоклеточного рака орофарингеальной зоны является сложным и многокомпонентным процессом. При этом большинству больных начинают лечение с проявлениями нутритивной недостаточности, являющейся следствием прогрессирования основного заболевания. Степень нутритивной недостаточности определяется локализацией и размерами первичного очага и, как правило, остается постоянным спутником данной категории пациентов на всех этапах лечения. Адекватная нутритивная поддержка позволяет снизить частоту осложнений после хирургического лечения и развития лучевых реакций, повысить переносимость лечения и улучшить качество жизни пациентов.
Список литературы
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4. Langius J.A., van Dijk A.M., Doornaert P. et al. More than 10 % weight loss in head and neck cancer patients during radiotherapy is independently associated with deterioration in quality of life. Nutr Cancer 2013;65(1):76–83.
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7. Langius J.A., Doornaert P., Spreeuwenberg M.D. et al. Radiotherapy on the neck nodes predicts severe weight loss inpatients with early stage laryngeal cancer. Radiother Oncol 2010;97(1):80–5.
8. Matthews T.W., Lampe H.B., Dragosz K. Nutritional status in head and neck cancer patients. J Otolaryngol 1995;24(2):87–91.
9. Unsal D., Mentes B., Akmansu M. et al. Evaluation of nutritionalstatus in cancer patients receiving radiotherapy: a prospective study. Am J Clin Oncol 2006;29(2):183–8.
10. Алиева С.Б. Химиолучевая терапия больных с местно-распространенным плоскоклеточным раком головы и шеи. Практическая онкология 2008;9(1):27–30. [Аlieva S.B. Chemical radial therapy of patients with locally spread flat head and neck cancer. Prakticheskaya onkologiya = Practical Oncology 2008;9(1):27–30. (In Russ.)].
11. Langius J.A., Zandbergen M.C., Eerenstein S.E. et al. Effect of nutritional interventions on nutritional status, quality of life and mortality in patients with head and neck cancer receiving (chemo)radiotherapy: a systematic review. Clin Nutr 2013;21(6):671–8.
12. van Bokhorst-de van der Schueren M.A., van Leeuwen P.A., Sauerwein H.P. et al. Assessment of malnutrition parameters in head and neck cancer and their relation to postoperative complications. Head Neck 1997;19(5):419–25.
13. de Luis D.A., Aller R., Izaola O. et al. Postsurgery enteral nutrition in head and neck cancer patients. Eur J Clin Nutr 2002;56(11):1126–9.
14. Луфт В.М., Луфт А.В. Нутриционная поддержка онкологических больных: возможности и противоречия. Вестник интенсивной терапии 2008;2:43–50. [Luft V.М., Luft А.V. Nutrition support of oncologic patients: possibilities and contradictions. Vestnik intensivnoy terapii = Intensive Therapy Herald 2008;2:43–50. (In Russ.)].
15. Практические рекомендации по нутритивной поддержке при химиотерапии и/или лучевой терапии. Доступно по ссылке: http://www.rosoncoweb.ru/standarts/RUSSCO/2-09.pdf. [Practical recommendations on the nutrition support at chemical and /or radial therapy. Available at: http://www.rosoncoweb.ru/standarts/RUSSCO/2-09.pdf/. (In Russ.)].
16. Решетов И.В., Егоров Г.Н. Предоперационная нутритивная терапия пациентов с опухолями головы и шеи. Голова и шея 2013;(2):27–34. [Reshetov I.V., Egorov G.N. Preоperational nutrition therapy of patients with head and neck tumors. Golova i sheya = Head and Neck 2013;(2):27–34. (In Russ.)].
17. Снеговой А.В., Салтанов А.И., Манзюк Л.В. и др. Оценка эффективности нутритивной поддержки энтеральной смесью «Фортикер» у пациентов с онкологическими заболеваниями в период лучевой и химиотерапии. Вестник интенсивной терапии 2009;(4):77–83. [Snegovoy А.V., Saltanov А.I., Маnzyuk L.V. et al. Evaluation of the efficiency of the nutrition support with Forticare enteral mixture at patients with oncologic diseases during the radial and chemical therapy. Vestnik intensivnoy terapii = Intensive Therapy Herald 2009;(4):77–83. (In Russ.)].
18. Elia M., van Bokhorst-de van Schueren M.A., Garvey J. et al. Enteral (oral or tube administration) nutritional support and eicosapentaenoic acid in patients with cancer: a systematic review. Int J Oncol 2006;28(1):5–23.
Head and Neck Tumors (HNT). 2015; 5: 13-15
Correction of malnutrition in patients with oropharyngeal squamous cell carcinoma
https://doi.org/10.17650/2222-1468-2015-5-3-13-15Abstract
To treat oropharyngeal squamous cell carcinoma is a complex and multicomponent process. In so doing, most patients starting treatment have already manifestations of malnutrition resulting from underlying disease progression. The degree of malnutrition is determined by the site and sizes of a primary focus and generally remains permanent in patients with oropharyngeal squamous cell carcinoma at all treatment steps. Adequate nutritional support makes it possible to reduce the incidence of complications after surgical treatment and development of radiation responses, to enhance tolerability of treatment, and to improve quality of life in patients.
References
1. Osipova N.A., Reshetov I.V., Sokolov V.V. i dr. Enteral'naya nutritivnaya podderzhka v khirurgii opukholei golovy i shei. Onkokhirurgiya 2010;2(4):22–5. [Osipova N.A., Reshetov I.V., Sokolov V.V. et al. Enteral nutrition support in the surgery of head and neck tumors. Onkokhirurgiya = Cancer Surgery 2010;2(4):22–5. (In Russ.)].
2. Meyer F., Fortin A., Wang C.S. et al. Predictors of severe acute and late toxicities in patients with localized head-and-neck cancer treated with radiation therapy. Int J Radiat Oncol Biol Phys 2012;82(4):1454–62.
3. Capuano G., Grosso A., Gentile P.C. et al. Influence of weight loss on outcomes in patients with head and neck cancer undergoing concomitant chemoradiotherapy. Head Neck 2008;30(4):503–8.
4. Langius J.A., van Dijk A.M., Doornaert P. et al. More than 10 % weight loss in head and neck cancer patients during radiotherapy is independently associated with deterioration in quality of life. Nutr Cancer 2013;65(1):76–83.
5. Andreyev H.J., Norman A.R., Oates J., Cunningham D. Why do patients with weight loss have a worse outcome when undergoing chemotherapy for gastrointestinal malignancies? Eur J Cancer 1998;34(4):503–9.
6. Regueiro C.A., Aragon G., Millan I. et al. Prognostic factors for local control, regional control and survival in oropharyngeal squamous cell carcinoma. Eur J Cancer 1994;30A(14):2060–7.
7. Langius J.A., Doornaert P., Spreeuwenberg M.D. et al. Radiotherapy on the neck nodes predicts severe weight loss inpatients with early stage laryngeal cancer. Radiother Oncol 2010;97(1):80–5.
8. Matthews T.W., Lampe H.B., Dragosz K. Nutritional status in head and neck cancer patients. J Otolaryngol 1995;24(2):87–91.
9. Unsal D., Mentes B., Akmansu M. et al. Evaluation of nutritionalstatus in cancer patients receiving radiotherapy: a prospective study. Am J Clin Oncol 2006;29(2):183–8.
10. Alieva S.B. Khimioluchevaya terapiya bol'nykh s mestno-rasprostranennym ploskokletochnym rakom golovy i shei. Prakticheskaya onkologiya 2008;9(1):27–30. [Alieva S.B. Chemical radial therapy of patients with locally spread flat head and neck cancer. Prakticheskaya onkologiya = Practical Oncology 2008;9(1):27–30. (In Russ.)].
11. Langius J.A., Zandbergen M.C., Eerenstein S.E. et al. Effect of nutritional interventions on nutritional status, quality of life and mortality in patients with head and neck cancer receiving (chemo)radiotherapy: a systematic review. Clin Nutr 2013;21(6):671–8.
12. van Bokhorst-de van der Schueren M.A., van Leeuwen P.A., Sauerwein H.P. et al. Assessment of malnutrition parameters in head and neck cancer and their relation to postoperative complications. Head Neck 1997;19(5):419–25.
13. de Luis D.A., Aller R., Izaola O. et al. Postsurgery enteral nutrition in head and neck cancer patients. Eur J Clin Nutr 2002;56(11):1126–9.
14. Luft V.M., Luft A.V. Nutritsionnaya podderzhka onkologicheskikh bol'nykh: vozmozhnosti i protivorechiya. Vestnik intensivnoi terapii 2008;2:43–50. [Luft V.M., Luft A.V. Nutrition support of oncologic patients: possibilities and contradictions. Vestnik intensivnoy terapii = Intensive Therapy Herald 2008;2:43–50. (In Russ.)].
15. Prakticheskie rekomendatsii po nutritivnoi podderzhke pri khimioterapii i/ili luchevoi terapii. Dostupno po ssylke: http://www.rosoncoweb.ru/standarts/RUSSCO/2-09.pdf. [Practical recommendations on the nutrition support at chemical and /or radial therapy. Available at: http://www.rosoncoweb.ru/standarts/RUSSCO/2-09.pdf/. (In Russ.)].
16. Reshetov I.V., Egorov G.N. Predoperatsionnaya nutritivnaya terapiya patsientov s opukholyami golovy i shei. Golova i sheya 2013;(2):27–34. [Reshetov I.V., Egorov G.N. Preoperational nutrition therapy of patients with head and neck tumors. Golova i sheya = Head and Neck 2013;(2):27–34. (In Russ.)].
17. Snegovoi A.V., Saltanov A.I., Manzyuk L.V. i dr. Otsenka effektivnosti nutritivnoi podderzhki enteral'noi smes'yu «Fortiker» u patsientov s onkologicheskimi zabolevaniyami v period luchevoi i khimioterapii. Vestnik intensivnoi terapii 2009;(4):77–83. [Snegovoy A.V., Saltanov A.I., Manzyuk L.V. et al. Evaluation of the efficiency of the nutrition support with Forticare enteral mixture at patients with oncologic diseases during the radial and chemical therapy. Vestnik intensivnoy terapii = Intensive Therapy Herald 2009;(4):77–83. (In Russ.)].
18. Elia M., van Bokhorst-de van Schueren M.A., Garvey J. et al. Enteral (oral or tube administration) nutritional support and eicosapentaenoic acid in patients with cancer: a systematic review. Int J Oncol 2006;28(1):5–23.
