Российские нанотехнологии. 2019; 14: 100-105
Оценка гемосовместимости наноструктурированных сфер гидроксиапатита различного размера
https://doi.org/10.21517/1992-7223-2019-7-8-100-105Аннотация
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Title in english. 2019; 14: 100-105
Assessment of hemocompatibility of nanostructured hydroxyapatite spheres of various sizes
https://doi.org/10.21517/1992-7223-2019-7-8-100-105Abstract
Synthetic nanostructured hydroxyapatite is promising for a wide range of applications in reconstructive medicine and implantology, as well as in cosmetology and dentistry. At the same time, by changing the synthesis conditions, for each specific direction of application, it is possible to adjust the characteristics of the material in accordance with the task.
We were using the method of chemical deposition and spray drying with ultrasonic treatment to obtain samples of nanostructured hydroxyapatite with different composition and size of granules. Analysis of hemocompatibility in experiments with mononuclear leukocytes and mouse blood erythrocytes showed that the obtained granule samples at a concentration of 40 mg per 2 ml of cell suspension are hemocompatible in all studied parameters, regardless of the size and composition of the spheres.
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