Офтальмохирургия. 2014; : 31-34
ИНТРАСТРОМАЛЬНАЯ КЕРАТОПЛАСТИКА С ИМПЛАНТАЦИЕЙ КОЛЕЦ MYORING В ХИРУРГИЧЕСКОМ ЛЕЧЕНИИ КЕРАТОКОНУСА. ПРЕДВАРИТЕЛЬНЫЕ РЕЗУЛЬТАТЫ
https://doi.org/undefinedАннотация
Цель. Изучить предварительные функциональные результаты имплантации интрастромальных роговичных колец MyoRing в хирургическом лечении кератоконуса.
Материал и методы. В обследуемую группу вошли 22 пациента (22 глаза) с прогрессирующим кератоконусом I-III стадии заболевания (по классификации Amsler), которым были имплантированы роговичные кольца MyoRing. Период наблюдения составил 9 мес.
Результаты. Повышение некорригированной остроты зрения после имплантации колец с 0,07Ѓ+0,05 до 0,47Ѓ+0,3 к концу срока наблюдения. Выявлены достоверные различия в величинах кератометрических показателей у всех пациентов и отдельно по возрастным группам до и после имплантации роговичных колец к концу срока наблюдения.
Выводы. Метод имплантации интрастромальных роговичных колец MyoRing способствует раннему и стабильному восстановлению визометрических, кератометрических, топографических, пахиметрических показателей глаз пациентов. Это позволяет использовать методику с целью замедления дальнейшего прогрессирования заболевания.
Список литературы
1. Balasubramanian S. A., Pye D.C., Willcox M.D. Are proteinases the reason for keratoconus? // Curr. Eye Res. – 2010. – № 3. – P. 185-191.
2. Bohringer D., Reinhard T., Godehardt E. et al. Regression analysis of idiopathic endothelial cell loss after perforating normal risk keratoplasty: basic principles for long-term analysis of endothelial risk factors in a retrospective clinical study // Klin. Monbl. Augenheilkd. – 2001. – № 6. – P. 412-417.
3. Collier S. A. Is the corneal degradation in keratoconus caused by matrix-metalloproteinases? // Clin. Exp. Ophthalmol. – 2001. – № 6. – P. 340-344.
4. Daxer A. Adjustable intracorneal ring in a lamellar pocket for keratoconus // J. Refract. Surg. – 2010. – № 3. – P. 217-221.
5. Ertan A., Colin J. Intracorneal rings for keratoconus and keratectasia // J. Cataract Refract. Surg. – 2007. – № 7. – P. 1303-1314.
6. Gabison E.E., Hoang-Xuan T., Mauviel A. et al. EMMPRIN/CD147, an MMP modulator in cancer, development and tissue repair // Biochemistry. – 2005. – № 3-4. – P. 361-368.
7. Gabison E.E., Huet E., Baudouin C. et al. Direct epithelial-stromal interaction in corneal wound healing: Role of EMMPRIN/ CD147 in MMPs induction and beyond // Prog. Retin. Eye Res. – 2009. – № 1. – P. 19-33.
8. Gabison E.E., Mourah S., Steinfels E. et al. Differential expression of extracellular matrix metalloproteinase inducer (CD147) in normal and ulcerated corneas: role in epithelio-stromal interactions and matrix metalloproteinase induction // Am. J. Pathol. – 2005. – № 1. – P. 209-219.
9. Gorovoy M.S., Gorovoy I.R., Ullman S. et al. Descemet stripping automated endothelial keratoplasty for spontaneous descemet membrane detachment in a patient with osteogenesis imperfect // Cornea. – 2012. – № 7. – P. 832-835.
10. Jabbarvand M., Salamatrad A., Hashemian H. et al. Continuous intracorneal ring implantation for keratoconus using a femtosecond laser // J. Cataract Refract. Surg. – 2013. – № 7. – P. 1081-1087.
11. Jabbarvand M., Salamatrad A., Hashemian H. et al. Continuous corneal intrastromal ring implantation for treatment of keratoconus in an Iranian population // Am. J. Ophthalmol. – 2013. – № 5. – P. 837-842.
12. Kenney M.C., Chwa M., Atilano S.R. et al. Increased levels of catalase and cathepsin V/L2 but decreased TIMP-1 in keratoconus corneas: evidence that oxidative stress plays a role in this disorder // Invest. Ophthalmol. Vis. Sci. – 2005. – № 3. – P. 823-832.
13. Kim M.H., Chung T.Y., Chung E.S. A retrospective contralateral study comparing deep anterior lamellar keratoplasty with penetrating keratoplasty // Cornea. – 2013. – № 4. – P. 385-389.
14. Koh S., Maeda N., Nakagawa T. et al. Characteristic higher-order aberrations of the anterior and posterior corneal surfaces in 3 corneal transplantation techniques // Am. J. Ophthalmol. – 2012. – № 2. – P. 284290.
15. Koh S., Maeda N., Nakagawa T. et al. Quality of vision in eyes after selective lamellar keratoplasty // Cornea. – 2012. – Vol. 31. – P. 45-49.
16. Kolomeyer A.M., Do B.K., Tu Y. et al. Placement of ProKera in the management of ocular manifestations of acute StevensJohnson syndrome in an outpatient // Eye Contact Lens. – 2013. – № 3. – P. 7-11.
17. Macintyre R., Chow S.P., Chan E. et al. Long-term Outcomes of Deep Anterior Lamellar Keratoplasty Versus Penetrating Keratoplasty in Australian Keratoconus Patients // Cornea. – 2013. – Vol. 33. – P. 6-9.
18. Mackiewicz Z., Maatta M., Stenman M. et al. Collagenolytic proteinases in keratoconus // Cornea. – 2006. – № 5. – P. 603-610.
19. Macpherson J.F., Slettedal J.K., Drolsum L. et al. Spontaneous hemorrhagic Descemet membrane detachment causing pupillary block // Eur. J. Ophthalmol. – 2012. – № 5. – P. 819-822.
20. Palioura S., Chodosh J., Pineda R. A novel approach to the management of a progressive Descemet membrane tear in a patient with keratoglobus and acute hydrops // Cornea. – 2013. – № 3. – P. 355-258.
21. Patel S.V., Baratz K.H., Maguire L.J. et al. Anterior corneal aberrations after Descemet’s stripping endothelial keratoplasty for Fuchs’ endothelial dystrophy // Ophthalmology. – 2012. – № 8. – P. 1522-1529.
22. Predović J., Balog T., Marotti T. et al. The expression of human corneal MMP2, MMP-9, proMMP-13 and TIMP-1 in bullous keratopathy and keratoconus // Coll. Antropol. – 2008. – № 2. – P. 15-19.
23. Robert M.C., Harasymowycz P. Hemorrhagic descemet detachment after combined canaloplasty and cataract surgery // Cornea. – 2013. – № 5. – P. 712-713.
24. Rudolph M., Laaser K., Bachmann B.O. et al. Corneal higher-order aberrations after Descemet’s membrane endothelial keratoplasty // Ophthalmology. – 2012. – № 3. – P. 528-535.
25. Said D.G., Ho S., Mathew M. et al. Rings around cones // Br. J. Ophthalmol. – 2009. – № 4. – P. 423.
26. Salustiano R., Avila M.P., Silva D.S. et al. Endothelial ana lysis in patients having corneal intrastromal surgery with Corneal ring for correction of Keratoconus // Semin.Ophthalmol. – 2013. – № 1. – P. 19-24.
27. Seppala H.P., Maatta M., Rautia M. et al. EMMPRIN and MMP-1 in keratoconus // Cornea. – 2006. – № 3. – P. 325-330.
Fyodorov Journal of Ophthalmic Surgery. 2014; : 31-34
INTRASTROMAL KERATOPLASTY WITH MYORING IMPLANTATION IN SURGICAL TREATMENT OF KERATOCONUS. PRELIMINARY RESULTS
https://doi.org/undefinedAbstract
Purpose. To study preliminary functional results in implantation of intrastromal corneal rings (MyoRing) in the surgical treatment of keratoconus.
Material and methods. The focus group included 22 patients (22 eyes) with progressive keratoconus of the stage I-III according to the Amsler classification, where corneal MyoRings were implanted. The mean follow-up w as 9 months.
Results. The uncorrected visual acuity (UCVA) after implantation of intrastromal corneal rings improved from 0.07Ѓ+0.05 to 0.47Ѓ+0.3 at the end of the follow-up. There were revealed significant differences in the values of keratometry indices in all patients and separately by age groups before and after implantation of corneal rings by the end of the follow-up.
Conclusions. The method of MyoRing implantation promotes an early and stable recovery of visometric, keratometric, topographic, pachimetric indices of patient’s eyes. It allows using the technique to delay a further progression of the disease.
References
1. Balasubramanian S. A., Pye D.C., Willcox M.D. Are proteinases the reason for keratoconus? // Curr. Eye Res. – 2010. – № 3. – P. 185-191.
2. Bohringer D., Reinhard T., Godehardt E. et al. Regression analysis of idiopathic endothelial cell loss after perforating normal risk keratoplasty: basic principles for long-term analysis of endothelial risk factors in a retrospective clinical study // Klin. Monbl. Augenheilkd. – 2001. – № 6. – P. 412-417.
3. Collier S. A. Is the corneal degradation in keratoconus caused by matrix-metalloproteinases? // Clin. Exp. Ophthalmol. – 2001. – № 6. – P. 340-344.
4. Daxer A. Adjustable intracorneal ring in a lamellar pocket for keratoconus // J. Refract. Surg. – 2010. – № 3. – P. 217-221.
5. Ertan A., Colin J. Intracorneal rings for keratoconus and keratectasia // J. Cataract Refract. Surg. – 2007. – № 7. – P. 1303-1314.
6. Gabison E.E., Hoang-Xuan T., Mauviel A. et al. EMMPRIN/CD147, an MMP modulator in cancer, development and tissue repair // Biochemistry. – 2005. – № 3-4. – P. 361-368.
7. Gabison E.E., Huet E., Baudouin C. et al. Direct epithelial-stromal interaction in corneal wound healing: Role of EMMPRIN/ CD147 in MMPs induction and beyond // Prog. Retin. Eye Res. – 2009. – № 1. – P. 19-33.
8. Gabison E.E., Mourah S., Steinfels E. et al. Differential expression of extracellular matrix metalloproteinase inducer (CD147) in normal and ulcerated corneas: role in epithelio-stromal interactions and matrix metalloproteinase induction // Am. J. Pathol. – 2005. – № 1. – P. 209-219.
9. Gorovoy M.S., Gorovoy I.R., Ullman S. et al. Descemet stripping automated endothelial keratoplasty for spontaneous descemet membrane detachment in a patient with osteogenesis imperfect // Cornea. – 2012. – № 7. – P. 832-835.
10. Jabbarvand M., Salamatrad A., Hashemian H. et al. Continuous intracorneal ring implantation for keratoconus using a femtosecond laser // J. Cataract Refract. Surg. – 2013. – № 7. – P. 1081-1087.
11. Jabbarvand M., Salamatrad A., Hashemian H. et al. Continuous corneal intrastromal ring implantation for treatment of keratoconus in an Iranian population // Am. J. Ophthalmol. – 2013. – № 5. – P. 837-842.
12. Kenney M.C., Chwa M., Atilano S.R. et al. Increased levels of catalase and cathepsin V/L2 but decreased TIMP-1 in keratoconus corneas: evidence that oxidative stress plays a role in this disorder // Invest. Ophthalmol. Vis. Sci. – 2005. – № 3. – P. 823-832.
13. Kim M.H., Chung T.Y., Chung E.S. A retrospective contralateral study comparing deep anterior lamellar keratoplasty with penetrating keratoplasty // Cornea. – 2013. – № 4. – P. 385-389.
14. Koh S., Maeda N., Nakagawa T. et al. Characteristic higher-order aberrations of the anterior and posterior corneal surfaces in 3 corneal transplantation techniques // Am. J. Ophthalmol. – 2012. – № 2. – P. 284290.
15. Koh S., Maeda N., Nakagawa T. et al. Quality of vision in eyes after selective lamellar keratoplasty // Cornea. – 2012. – Vol. 31. – P. 45-49.
16. Kolomeyer A.M., Do B.K., Tu Y. et al. Placement of ProKera in the management of ocular manifestations of acute StevensJohnson syndrome in an outpatient // Eye Contact Lens. – 2013. – № 3. – P. 7-11.
17. Macintyre R., Chow S.P., Chan E. et al. Long-term Outcomes of Deep Anterior Lamellar Keratoplasty Versus Penetrating Keratoplasty in Australian Keratoconus Patients // Cornea. – 2013. – Vol. 33. – P. 6-9.
18. Mackiewicz Z., Maatta M., Stenman M. et al. Collagenolytic proteinases in keratoconus // Cornea. – 2006. – № 5. – P. 603-610.
19. Macpherson J.F., Slettedal J.K., Drolsum L. et al. Spontaneous hemorrhagic Descemet membrane detachment causing pupillary block // Eur. J. Ophthalmol. – 2012. – № 5. – P. 819-822.
20. Palioura S., Chodosh J., Pineda R. A novel approach to the management of a progressive Descemet membrane tear in a patient with keratoglobus and acute hydrops // Cornea. – 2013. – № 3. – P. 355-258.
21. Patel S.V., Baratz K.H., Maguire L.J. et al. Anterior corneal aberrations after Descemet’s stripping endothelial keratoplasty for Fuchs’ endothelial dystrophy // Ophthalmology. – 2012. – № 8. – P. 1522-1529.
22. Predović J., Balog T., Marotti T. et al. The expression of human corneal MMP2, MMP-9, proMMP-13 and TIMP-1 in bullous keratopathy and keratoconus // Coll. Antropol. – 2008. – № 2. – P. 15-19.
23. Robert M.C., Harasymowycz P. Hemorrhagic descemet detachment after combined canaloplasty and cataract surgery // Cornea. – 2013. – № 5. – P. 712-713.
24. Rudolph M., Laaser K., Bachmann B.O. et al. Corneal higher-order aberrations after Descemet’s membrane endothelial keratoplasty // Ophthalmology. – 2012. – № 3. – P. 528-535.
25. Said D.G., Ho S., Mathew M. et al. Rings around cones // Br. J. Ophthalmol. – 2009. – № 4. – P. 423.
26. Salustiano R., Avila M.P., Silva D.S. et al. Endothelial ana lysis in patients having corneal intrastromal surgery with Corneal ring for correction of Keratoconus // Semin.Ophthalmol. – 2013. – № 1. – P. 19-24.
27. Seppala H.P., Maatta M., Rautia M. et al. EMMPRIN and MMP-1 in keratoconus // Cornea. – 2006. – № 3. – P. 325-330.
