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Журнал микробиологии, эпидемиологии и иммунобиологии. 2019; : 82-89

Varicella Zoster-вирусная инфекция: иммунитет, диагностика и моделирование in vivo

Лавров В. Ф., Свитич О. А., Казанова А. С., Кинкулькина А. Р., Зверев В. В.

https://doi.org/10.36233/0372-9311-2019-4-82-89

Аннотация

Varicella Zoster Virus (VZV) — высоко контагиозный вирусный агент семейства Herpesviridae, обладающий строгой видовой специфичностью и вызывающий два различных заболевания — ветряную оспу, преимущественно у детей, и опоясывающий герпес — чаще у пожилых людей. Получение дополнительных сведений о жизненном цикле вируса, его биологии, патогенетических особенностях вызываемых им осложнений будет способствовать появлению более совершенных методов диагностики и профилактики, разработке новых экспериментальных подходов, позволяющих изучать врожденные и адаптивные механизмы иммунной защиты при VZV-инфекции.

Список литературы

1. Ганковская О.А., Бахарева И.В., Ганковская Л.В. Исследование экспрессии генов TLR9, NF-КB, ФНОα в клетках слизистой цервикального канала беременных с герпесвирусной инфекцией. Журн. микробиол. 2009, 2: 61-64.

2. Григорьева О.Ю. Роль TLR9 в противогерпетическом иммунитете. Влияние науки на инновационное развитие. Сборник статей международной научно-практической конференции. 2017, 2: 7-9.

3. Казанова А.С., Лавров В.Ф., Зверев В.В. Вирус varicella zoster и заболевания сосудов центральной нервной системы. Журн. микробиол. 2015, 3: 106-116.

4. Казанова А.С., Лавров В.Ф., Дубоделов Д.В. и др. Ветряная оспа и опоясывающий лишай: история и перспективы вакцинопрофилактики. Эпидемиология и инфекционные болезни. Актуальные вопросы. 2011, 2: 36-39.

5. Лавров В.Ф., Казанова А.С., Кузин С.Н. и др. Ветряная оспа и опоясывающий лишай: особенности заболеваемости и клинических проявлений. Эпидемиология и инфекционные болезни. Актуальные вопросы, 2011, 3: 54-58.

6. Aronson P.L., Lyons T.W., Cruz A. Impact of Enteroviral Polymerase Chain Reaction Testing on Length of Stay for Infants 60 Days Old or Younger. J. Pediatr. 2017, 189: 169-174.

7. Depledge D.P., Kundu S.Т., Jensen N.J. et al. Deep sequencing of viral genomes provides insight into the evolution and pathogenesis of varicella zoster virus and its vaccine in humans. Mol Biol Evol. 2014, 31(2): 397-409.

8. Elwee M.N., Vijayakrishnan S.N., Rixon F et al. Structure of the herpes simplex virus portal-vertex. PLoSBiol. 2018, 16(6): 526-535.

9. Galassi G.N., Genovese M.N., Meacci M. et al. Comment on ischemic stroke after herpes zoster. J Med Virol. 2018, 5(6): 167-175.

10. Gershon A.A., Gershon M.D. Pathogenesis and current approaches to control of varicella-zoster virus infections. Clin Microbiol Rev. 2013, 26(4): 728-743.

11. L’Huillier A.G., Ferry T., Courvoisier D.S. et al. Impaired antibody memory to varicella zoster virus in HIV-infected children: low antibody levels and avidity. HIV Med. 2012, 13(1): 54-61.

12. Kanbayashi Y.N., Matsumoto Y.N. Predicting risk factors for varicella zoster virus infection and posthe rpetic neuralgia after hematopoietic cell transplantation using ordered logistic regression analysis. Ann Hematol. 2017, 96(2): 311-315.

13. Kim S.K., Kim M.C., Han S.B. et al. Clinical characteristics and outcomes of varicella zoster virus infection in children with hematologic malignancies in the acyclovir era. Blood Res. 2016, 51(4): 249-255.

14. Kennedy P.G., Rovnak J.N., Badani H. et al. A comparison of herpes simplex virus type 1 and varicellazoster virus latency and reactivation. J. Gen. Virol. 2015, 96(7): 1581-1602.

15. Komadina N.N., McVernon J.N., Hall R. et al. A historical perspective of influenza A(H1N2) virus. Emerg. Infect. Dis. 2014, 20(1): 6-12.

16. Kovalchuk L.V., Gankovskaya L.V., Gankovskaya O.A., Lavrov V.F. et al. Herpes simplex virus: treatment with antimicrobial peptides. Advancesin Experimental Medicine and Biology. 2007, 601: 369-376.

17. Li Y., Zhu B. et al. Genotyping of clinical varicella-zoster virus isolates collected from Yunnan in Southwestern China. Biomed Rep. 2016, 4(2): 209-214.

18. Mathew T., Thomas K., Shivde S. et al. Post herpes zoster infection neuromyelitis optica spectrum disorder. Mult Scler Relat Disord. 2017, 18: 93-94.

19. Norberg P., Depledge D.P., Kundu S. et al. Recombination of Globally Circulating Varicella-Zoster Virus. Depledge. J Virol. 2015, 89(14): 7133-7146.

20. Ojha R.P., Stallings-Smith S., Aviles-Robles M.J. et al. Incidence and case fatality of varicella zoster virus infection among pediatriccancer patients in developing countries. Eur J Pediatr. 2016, 175(4): 581-586.

21. Park S.Y., Kim J.Y., Kim J.A. et al. Diagnostic Usefulness of Varicella-Zoster Virus Real-Time Polymerase Chain Reaction Analysis of DNA in Saliva and Plasma Specimens From Patients With Herpes Zoster. J Infect Dis. 2017, 217(1): 51-57.

22. Suenaga T., Matsumoto M., Arisawa F. et al. Sialic Acid on Varicella-Zoster Virus Glycoprotein B Are Required for Cell-Cell Fusion. J Biol Chem. 2015, 290(32): 19833-19843.

23. Sauerbrei A. Diagnosis, antiviral therapy and prophylaxis of varicella-zoster virus infections. Eur J Clin Microbiol Infect Dis. 2016, 35(5): 723-734.

24. Science M., MacGregor D., Richardson S.E. et al. Central nervous system complications of varicellazoster virus. J Pediatr. 2014, 165(4): 779-785.

25. Svitich O.A., Gankovskaya L.V., Lavrov V.F. Herpes simplex virus type 2 infection during pregnancy is correlated with elevated TLR9 and TNFα expression in cervical cells. International Trends in Immunity. 2014, 2(1): 62-66.

26. Weller T.H. Intradermal vaccination against influenza. N Engl J Med. 2005, 352(10): 1044-1046.

Journal of microbiology, epidemiology and immunobiology. 2019; : 82-89

Varicella Zoster virus infection: immunity, diagnosis and modelling in vivo

Lavrov V. F., Svitich O. A., Kazanova A. S., Kinkulkina A. R., Zverev V. V.

https://doi.org/10.36233/0372-9311-2019-4-82-89

Abstract

Varicella Zoster Virus (VZV) is a highly contagious viral agent of the Herpesviridae family, which has a strict species specificity, and causes two different diseases — chickenpox, mainly in children, and herpes zoster — more often in the elderly. Obtaining additional information about the life cycle of the virus, its biology, pathogenetic features of the complications caused by it, will contribute to the emergence of more advanced methods of diagnosis and prevention, the development of new experimental approaches that allow to study the innate and adaptive mechanisms of immune protection in VZV-infection.

References

1. Gankovskaya O.A., Bakhareva I.V., Gankovskaya L.V. Issledovanie ekspressii genov TLR9, NF-KB, FNOα v kletkakh slizistoi tservikal'nogo kanala beremennykh s gerpesvirusnoi infektsiei. Zhurn. mikrobiol. 2009, 2: 61-64.

2. Grigor'eva O.Yu. Rol' TLR9 v protivogerpeticheskom immunitete. Vliyanie nauki na innovatsionnoe razvitie. Sbornik statei mezhdunarodnoi nauchno-prakticheskoi konferentsii. 2017, 2: 7-9.

3. Kazanova A.S., Lavrov V.F., Zverev V.V. Virus varicella zoster i zabolevaniya sosudov tsentral'noi nervnoi sistemy. Zhurn. mikrobiol. 2015, 3: 106-116.

4. Kazanova A.S., Lavrov V.F., Dubodelov D.V. i dr. Vetryanaya ospa i opoyasyvayushchii lishai: istoriya i perspektivy vaktsinoprofilaktiki. Epidemiologiya i infektsionnye bolezni. Aktual'nye voprosy. 2011, 2: 36-39.

5. Lavrov V.F., Kazanova A.S., Kuzin S.N. i dr. Vetryanaya ospa i opoyasyvayushchii lishai: osobennosti zabolevaemosti i klinicheskikh proyavlenii. Epidemiologiya i infektsionnye bolezni. Aktual'nye voprosy, 2011, 3: 54-58.

6. Aronson P.L., Lyons T.W., Cruz A. Impact of Enteroviral Polymerase Chain Reaction Testing on Length of Stay for Infants 60 Days Old or Younger. J. Pediatr. 2017, 189: 169-174.

7. Depledge D.P., Kundu S.T., Jensen N.J. et al. Deep sequencing of viral genomes provides insight into the evolution and pathogenesis of varicella zoster virus and its vaccine in humans. Mol Biol Evol. 2014, 31(2): 397-409.

8. Elwee M.N., Vijayakrishnan S.N., Rixon F et al. Structure of the herpes simplex virus portal-vertex. PLoSBiol. 2018, 16(6): 526-535.

9. Galassi G.N., Genovese M.N., Meacci M. et al. Comment on ischemic stroke after herpes zoster. J Med Virol. 2018, 5(6): 167-175.

10. Gershon A.A., Gershon M.D. Pathogenesis and current approaches to control of varicella-zoster virus infections. Clin Microbiol Rev. 2013, 26(4): 728-743.

11. L’Huillier A.G., Ferry T., Courvoisier D.S. et al. Impaired antibody memory to varicella zoster virus in HIV-infected children: low antibody levels and avidity. HIV Med. 2012, 13(1): 54-61.

12. Kanbayashi Y.N., Matsumoto Y.N. Predicting risk factors for varicella zoster virus infection and posthe rpetic neuralgia after hematopoietic cell transplantation using ordered logistic regression analysis. Ann Hematol. 2017, 96(2): 311-315.

13. Kim S.K., Kim M.C., Han S.B. et al. Clinical characteristics and outcomes of varicella zoster virus infection in children with hematologic malignancies in the acyclovir era. Blood Res. 2016, 51(4): 249-255.

14. Kennedy P.G., Rovnak J.N., Badani H. et al. A comparison of herpes simplex virus type 1 and varicellazoster virus latency and reactivation. J. Gen. Virol. 2015, 96(7): 1581-1602.

15. Komadina N.N., McVernon J.N., Hall R. et al. A historical perspective of influenza A(H1N2) virus. Emerg. Infect. Dis. 2014, 20(1): 6-12.

16. Kovalchuk L.V., Gankovskaya L.V., Gankovskaya O.A., Lavrov V.F. et al. Herpes simplex virus: treatment with antimicrobial peptides. Advancesin Experimental Medicine and Biology. 2007, 601: 369-376.

17. Li Y., Zhu B. et al. Genotyping of clinical varicella-zoster virus isolates collected from Yunnan in Southwestern China. Biomed Rep. 2016, 4(2): 209-214.

18. Mathew T., Thomas K., Shivde S. et al. Post herpes zoster infection neuromyelitis optica spectrum disorder. Mult Scler Relat Disord. 2017, 18: 93-94.

19. Norberg P., Depledge D.P., Kundu S. et al. Recombination of Globally Circulating Varicella-Zoster Virus. Depledge. J Virol. 2015, 89(14): 7133-7146.

20. Ojha R.P., Stallings-Smith S., Aviles-Robles M.J. et al. Incidence and case fatality of varicella zoster virus infection among pediatriccancer patients in developing countries. Eur J Pediatr. 2016, 175(4): 581-586.

21. Park S.Y., Kim J.Y., Kim J.A. et al. Diagnostic Usefulness of Varicella-Zoster Virus Real-Time Polymerase Chain Reaction Analysis of DNA in Saliva and Plasma Specimens From Patients With Herpes Zoster. J Infect Dis. 2017, 217(1): 51-57.

22. Suenaga T., Matsumoto M., Arisawa F. et al. Sialic Acid on Varicella-Zoster Virus Glycoprotein B Are Required for Cell-Cell Fusion. J Biol Chem. 2015, 290(32): 19833-19843.

23. Sauerbrei A. Diagnosis, antiviral therapy and prophylaxis of varicella-zoster virus infections. Eur J Clin Microbiol Infect Dis. 2016, 35(5): 723-734.

24. Science M., MacGregor D., Richardson S.E. et al. Central nervous system complications of varicellazoster virus. J Pediatr. 2014, 165(4): 779-785.

25. Svitich O.A., Gankovskaya L.V., Lavrov V.F. Herpes simplex virus type 2 infection during pregnancy is correlated with elevated TLR9 and TNFα expression in cervical cells. International Trends in Immunity. 2014, 2(1): 62-66.

26. Weller T.H. Intradermal vaccination against influenza. N Engl J Med. 2005, 352(10): 1044-1046.