Валеология: Здоровье, Болезнь, Выздоровление. 2021; : 24-29
ЭПИДЕМИОЛОГИЧЕСКИЕ И КЛИНИЧЕСКИЕ ХАРАКТЕРИСТИКИ COVID-19 В КАЗАХСТАНЕ
Аннотация
Исследование направлено на изучение клинико-эпидемиологических показателей у пациентов с COVID-19 в Республике Казахстан, а также выявление факторов, влияющих на тяжесть заболевания. Всего было проанализировано 517 историй болезни пациентов с COVID-19, находившихся на стационарном лечении с 23 марта по 30 апреля, из базы ЭРСБ (электронных историй болезней пациентов) со всех регионов Казахстана. Из 517 пациентов с диагнозом COVID-19 количество женщин составило 52,8 %. Среди заболевших поездки за пределы страны в течение 14 дней до начала заболевания имело достоверное значение (0,005) для всех возрастных групп, но не отразилось на тяжести течения. Наиболее часто заболевание регистрировалось у обследованных по контакту (р = 0,002). Бессимптомное носительство вируса SARS-CoV-2 чаще встречается среди мужчин (76 %), легкое течение (55 %), средней или тяжелой степени тяжести (53 %) среди женщин. Наиболее частыми клиническими проявлениями COVID-19 является повышение температуры тела, чаще всего регистрируются субфебрилитет, кашель, слабость. Необходимо отметить, что из 517 обследуемых лиц 172 контактных (33 %) в последующем реализовали клинику COVID-19 легкой и средней степени тяжести.
Список литературы
1. Tan W., Zhao X., Ma X., et al. A Novel Coronavirus from Patients with Pneumonia in China // The New England journal of medicine. 2019. № 382 (8). Р. 727–733. https://doi.org/10.1056/NEJMoa2001017.
2. Отчет Всемирной организации здравоохранения (2020) по коронавирусной инфекции 2019 (COVID-19) – 39. Всемирная организация здравоохранения, Женева. https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200228-sitrep-39-covid-19.pdf?sfvrsn=5bbf3e7d_2.
3. Chen H. D., Chen J., Luo Y., et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin // Nature. 2020. № 579. Р. 270–3.
4. Liu H., Gao J., Wang Y., et al. Epidemiological and clinical characteristics of 2019 novel coronavirus disease (COVID-19) in Jilin, China: A descriptive study //Medicine (Baltimore). 2020. Vol. 20 № 99(47): e23407. doi: 10.1097/MD.0000000000023407.
5. Liu J., Zheng X., Tong Q., et al. Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS ‐ CoV, MERS ‐ CoV, and 2019 ‐ nCoV // J Medicine Virology. 2020. № 92. Р. 491–4.
6. Wu D., Wu T., Liu Q., Yang Z. The SARS ‐ CoV ‐ 2 outbreak: what we know // International Journal of Infectious Diseases. 2020. № 94. P. 44–8.
7. Pascarella, G., Strumia, A., Piliego, C., et al. COVID-19 diagnosis and management: a comprehensive review // Journal of internal medicine. 2020. № 288 (2). P. 192–206. https://doi.org/10.1111/joim.13091
8. Lian J. et al. Epidemiological, clinical, and virological characteristics of 465 hospitalized cases of coronavirus disease 2019 (COVID ‐ 19) from Zhejiang province in China //Influenza and other respiratory viruses. 2020. № 14 (5). Р. 564–574.
9. Nanshan Chen M. Z., Xuan D., Jieming Q., et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study // Lancet (London, England). 2020. № 7 (20). Р. S0140 ‐ 6736.
Valeology: Health - Illnes - recovery. 2021; : 24-29
EPIDEMIOLOGICAL AND CLINICAL CHARACTERISTICS OF COVID-19 IN KAZAKHSTAN
Abstract
The research is directed to study clinical and epidemiological indicators of patients with COVID-19 in the Republic of Kazakhstan, as well as to identify factors that affect to a burden of disease. There were 517 history diseases analyzed from patients with COVID-19 from March 23 to April 30 during they had been on in-patient treatment. They were taken from the EPHD database (electronic patients' history diseases) from all over the regions of Kazakhstan. There were 52.8 % of women among the 517 patients with COVID-19. Travelling outside the country within 14 days before the beginning of disease had a certain value (0.005) for all age groups, but did not reflected on burden of current. The patients analyzed for disease by contact (p = 0.002) were registered most frequently. We are meeting asymptomatic carriage of the SARS-CoV-2 virus more often among men (76 %), mild current (55 %), and moderate or severe (53%) among women. Rise in temperature, often registered sub febrility, cough and weakness are the most frequent clinical manifestations of COVID-19. It should be noted that out of 517 being analyzed persons, 172 contact persons (33 %) subsequently realized mild and moderate clinic of COVID-19.
References
1. Tan W., Zhao X., Ma X., et al. A Novel Coronavirus from Patients with Pneumonia in China // The New England journal of medicine. 2019. № 382 (8). R. 727–733. https://doi.org/10.1056/NEJMoa2001017.
2. Otchet Vsemirnoi organizatsii zdravookhraneniya (2020) po koronavirusnoi infektsii 2019 (COVID-19) – 39. Vsemirnaya organizatsiya zdravookhraneniya, Zheneva. https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200228-sitrep-39-covid-19.pdf?sfvrsn=5bbf3e7d_2.
3. Chen H. D., Chen J., Luo Y., et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin // Nature. 2020. № 579. R. 270–3.
4. Liu H., Gao J., Wang Y., et al. Epidemiological and clinical characteristics of 2019 novel coronavirus disease (COVID-19) in Jilin, China: A descriptive study //Medicine (Baltimore). 2020. Vol. 20 № 99(47): e23407. doi: 10.1097/MD.0000000000023407.
5. Liu J., Zheng X., Tong Q., et al. Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS ‐ CoV, MERS ‐ CoV, and 2019 ‐ nCoV // J Medicine Virology. 2020. № 92. R. 491–4.
6. Wu D., Wu T., Liu Q., Yang Z. The SARS ‐ CoV ‐ 2 outbreak: what we know // International Journal of Infectious Diseases. 2020. № 94. P. 44–8.
7. Pascarella, G., Strumia, A., Piliego, C., et al. COVID-19 diagnosis and management: a comprehensive review // Journal of internal medicine. 2020. № 288 (2). P. 192–206. https://doi.org/10.1111/joim.13091
8. Lian J. et al. Epidemiological, clinical, and virological characteristics of 465 hospitalized cases of coronavirus disease 2019 (COVID ‐ 19) from Zhejiang province in China //Influenza and other respiratory viruses. 2020. № 14 (5). R. 564–574.
9. Nanshan Chen M. Z., Xuan D., Jieming Q., et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study // Lancet (London, England). 2020. № 7 (20). R. S0140 ‐ 6736.
