Валеология: Здоровье, Болезнь, Выздоровление. 2020; : 92-96
СОСТОЯНИЕ ИММУННОЙ СИСТЕМЫ ПРИ COVID-19, СИМПТОМЫ И КЛИНИЧЕСКИЕ ПРОЯВЛЕНИЯ У ДЕТЕЙ
Аннотация
11 марта 2020 года Всемирная Организация Здравоохранения (ВОЗ) объявила о пандемии коронавирусной инфекции (COVID-19), вызванной новым видом короновируса-2 (SARS-CoV-2), которая проявляется в виде тяжелого острого респираторного синдрома. В данном обзоре мы рассмотрим некоторые аспекты иммунной системы при COVID-19, а также клинические проявления (COVID-19) у детей.
Список литературы
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18. Zeng Q. et al. Mortality of COVID-19 is associated with cellular immune function compared to immune function in Chinese Han population // Medrxiv. – 2020.
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20. Diao B. et al. Reduction and functional exhaustion of T cells in patients with coronavirus disease 2019 (COVID-19) // Frontiers in Immunology. – 2020. – V. 11. – P. 827.
21. Liu J. et al. Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients // EBioMedicine. – 2020. – P. 102763.
22. Zhou Y. et al. Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients // National Science Review. – 2020.
23. Zhou Y. et al. A new predictor of disease severity in patients with COVID-19 in Wuhan, China // medRxiv. – 2020.
24. Tan L. et al. Lymphopenia predicts disease severity of COVID-19: a descriptive and predictive study // Signal transduction and targeted therapy. – 2020. – V. 5. –№ 1. – P. 1-3.
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26. Huang A. T. et al. A systematic review of antibody mediated immunity to coronaviruses: antibody kinetics, correlates of protection, and association of antibody responses with severity of disease // MedRxiv. – 2020.
27. Vabret N. et al. Immunology of COVID-19: current state of the science // Immunity. – 2020.
28. Dong Y. et al. Epidemiology of COVID-19 Among Children in China // Pediatrics. 2020. Vol.145, № 6.
29. Lu X. et al. SARS-CoV-2 infection in children // New England Journal of Medicine. – 2020. –Vol. 382. –№.17. – P. 1663-1665.
30. Yang W. et al. Clinical characteristics and imaging manifestations of the 2019 novel coronavirus disease (COVID-19): A multi-center study in Wenzhou city, Zhejiang, China // Journal of Infection. – 2020.
Valeology: Health - Illnes - recovery. 2020; : 92-96
STATE OF THE IMMUNE SYSTEM IN COVID-19, SYMPTOMS AND CLINICAL MANIFESTATIONS IN CHILDREN
Abstract
The World Health Organization (WHO) announced on March 11, 2020, a pandemic of coronаvirus infection (COVID-19) caused by a new type of coronovirus-2 (SARS-CoV-2), which manifests as severe acute respiratory syndrome. In this review, we will look at some aspects of the immune system in COVID-19, and clinical manifestations (COVID-19) in children.
References
1. Jiatong S., Wenjun L. Epidemiological characteristics and prevention and control measures of Corona Virus Disease 2019 in children // J Trop Med. – 2020. – Vol. 20. – №. 2. – P. 153-156.
2. Zhu N. et al. A novel coronavirus from patients with pneumonia in China, 2019 // New England Journal of Medicine. – 2020.
3. Ren L. L. et al. Identification of a novel coronavirus causing severe pneumonia in human: a descriptive study // Chinese medical journal. – 2020.
4. She J., Liu L., Liu W. COVID‐19 epidemic: disease characteristics in children // Journal of medical virology. – 2020.
5. World Health Organization (WHO). WHO characterizes COVID‐19 as a pandemic [EB/OL]. Geneva, Switzerland: World Health Organization; 2020. – https://pubmed.ncbi.nlm.nih.gov/32191675/
6. Fehr A. R., Perlman S. Coronaviruses: an overview of their replication and pathogenesis // Coronaviruses. – Humana Press, New York, NY, 2015. – P. 1-23.
7. Gorbalenya A. et al. Coronaviridae Study Group of the International Committee on Taxonomy of Viruses. The species severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2 // Nature microbiology. – 2020. – V. 2020. – P. 03-04.
8. Zhou P. et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin // Nature. – 2020. – V. 579. – №. 7798. – P. 270-273.
9. Andersen K. G. et al. The proximal origin of SARS-CoV-2 // Nature medicine. – 2020. – V. 26. – №. 4. – P. 450-452.
10. Jia H. P. et al. ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia // Journal of virology. – 2005. – V. 79. – №. 23. – P. 14614-14621.
11. Xu H. et al. High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa // International journal of oral science. – 2020. – V. 12. – №. 1. – P. 1-5.
12. Hamming I. et al. Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis // The Journal of Pathology: A Journal of the Pathological Society of Great Britain and Ireland. – 2004. – V. 203. – №. 2. – P. 631-637.
13. Kuba K., Imai Y., Penninger J. M. Angiotensin-converting enzyme 2 in lung diseases // Current opinion in pharmacology. – 2006. – V. 6. – №. 3. – P. 271-276.
14. Tay M. Z. et al. The trinity of COVID-19: immunity, inflammation and intervention // Nature Reviews Immunology. – 2020. – P. 1-12.
15. Huang C. et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China // The lancet. – 2020. – V. 395.– №.10223.– P. 497-506.
16. Chen G. et al. Clinical and immunological features of severe and moderate coronavirus disease 2019 // The Journal of clinical investigation. – 2020. – V. 130. – №. 5.
17. Nie J. et al. Establishment and validation of a pseudovirus neutralization assay for SARS-CoV-2 // Emerging microbes & infections. – 2020. – V. 9. – №. 1. – P. 680-686.
18. Zeng Q. et al. Mortality of COVID-19 is associated with cellular immune function compared to immune function in Chinese Han population // Medrxiv. – 2020.
19. Zheng M. et al. Functional exhaustion of antiviral lymphocytes in COVID-19 patients // Cellular & molecular immunology. – 2020. –V. 17. – №. 5. – P. 533-535.
20. Diao B. et al. Reduction and functional exhaustion of T cells in patients with coronavirus disease 2019 (COVID-19) // Frontiers in Immunology. – 2020. – V. 11. – P. 827.
21. Liu J. et al. Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients // EBioMedicine. – 2020. – P. 102763.
22. Zhou Y. et al. Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients // National Science Review. – 2020.
23. Zhou Y. et al. A new predictor of disease severity in patients with COVID-19 in Wuhan, China // medRxiv. – 2020.
24. Tan L. et al. Lymphopenia predicts disease severity of COVID-19: a descriptive and predictive study // Signal transduction and targeted therapy. – 2020. – V. 5. –№ 1. – P. 1-3.
25. Thevarajan I. et al. Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19 // Nature medicine. – 2020. –V. 26. –№.4. –P. 453-455.
26. Huang A. T. et al. A systematic review of antibody mediated immunity to coronaviruses: antibody kinetics, correlates of protection, and association of antibody responses with severity of disease // MedRxiv. – 2020.
27. Vabret N. et al. Immunology of COVID-19: current state of the science // Immunity. – 2020.
28. Dong Y. et al. Epidemiology of COVID-19 Among Children in China // Pediatrics. 2020. Vol.145, № 6.
29. Lu X. et al. SARS-CoV-2 infection in children // New England Journal of Medicine. – 2020. –Vol. 382. –№.17. – P. 1663-1665.
30. Yang W. et al. Clinical characteristics and imaging manifestations of the 2019 novel coronavirus disease (COVID-19): A multi-center study in Wenzhou city, Zhejiang, China // Journal of Infection. – 2020.
