Вопросы гематологии/онкологии и иммунопатологии в педиатрии. 2024; 23: 174-181
Влияние тромботических событий при челюстно-лицевой патологии детского возраста на результаты хирургического лечения
https://doi.org/10.24287/1726-1708-2024-23-4-174-181Аннотация
Локальные и генерализованные тромботические события могут влиять на результаты лечения и качество жизни пациентов. Целью нашего систематического обзора литературы было исследование влияния тромботических событий при челюстно-лицевой патологии детского возраста на результаты хирургического лечения. Поиск публикаций проведен в декабре 2023 г. в информационной системе PubMed. Два автора независимо рассмотрели исследования и извлекли данные для анализа. В исследование вошли 8 публикаций из 654 найденных. Педиатрическая когорта в отобранных исследованиях была смешана со взрослыми пациентами. Получено недостаточно информации для выполнения метаанализа и четкого ответа на вопрос исследования. Представляется вероятным, что анатомо-патофизиологические особенности челюстно-лицевой патологии, фармакологические эффекты терапии и методы хирургической коррекции могут влиять на развитие и прогрессирование локальной внутрисосудистой коагулопатии. Рекомендации по выбору стандартных или интегральных тестов гемостаза для диагностики и мониторинга коагулопатии при данной патологии отсутствуют. Применение низкомолекулярных гепаринов может уменьшить клинические проявления локальной внутрисосудистой коагулопатии.
Список литературы
1. Kushner A., West W.P., Khan Suheb M.Z., Pillarisetty L.S. Virchow Triad. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan.
2. Martinelli I., Bucciarelli P., Mannucci P.M. Thrombotic risk factors: basic pathophysiology. Crit Care Med 2010; 38 (2 Suppl): S3–9. DOI: 10.1097/CCM.0b013e3181c9cbd9
3. Crochemore T., Görlinger K., Lance M.D. Early Goal-Directed Hemostatic Therapy for Severe Acute Bleeding Management in the Intensive Care Unit: A Narrative Review. Anesth Analg 2024; 138 (3): 499–513. DOI: 10.1213/ANE.0000000000006756
4. Tricco A.C., Lillie E., Zarin W., O'Brien K.K., Colquhoun H., Levac D., et al. PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation. Ann Intern Med 2018; 169 (7): 467–73. DOI: 10.7326/M18-0850
5. Rossell-Perry P. Flap Necrosis after Palatoplasty in Patients with Cleft Palate. Biomed Res Int 2015; 2015: 516375. DOI: 10.1155/2015/516375
6. Omesiete W.I., Walker J.A. 3rd, Yu J.C. Venous Thromboembolism Incidence After Craniofacial Surgery. Ann Plast Surg 2018; 80 (5): 561–4. DOI: 10.1097/SAP.0000000000001353
7. Forouzanfar T., Heymans M.W., van Schuilenburg A., Zweegman S., Schulten E.A. Incidence of venous thromboembolism in oral and maxillofacial surgery: a retrospective analysis. Int J Oral Maxillofac Surg 2010; 39 (3): 256–9. DOI: 10.1016/j.ijom.2009.10.024
8. Zhang C., Sun J., Zhu H., Xu L., Ji T., He Y., et al. Microsurgical free flap reconstructions of the head and neck region: Shanghai experience of 34 years and 4640 flaps. Int J Oral Maxillofac Surg 2015; 44 (6): 675– 84. DOI: 10.1016/j.ijom.2015.02.017
9. Hoffman G.R., Islam S., Eisenberg R.L. Microvascular reconstruction of the mouth, jaws, and face: experience of an Australian oral and maxillofacial surgery unit. J Oral Maxillofac Surg 2012; 70 (5): e371– 7. DOI: 10.1016/j.joms.2012.01.016
10. Jia Y., Zhao Y., Chen X. Clinical and histopathological review of 229 cases of ranula. J Huazhong Univ Sci Technolog Med Sci 2011; 31 (5): 717. DOI: 10.1007/s11596-011-0589-7
11. Jonas R., Schaal T., Krimmel M., Gülicher D., Reinert S., Hoffmann J. Monitoring in microvascular tissue transfer by measurement of oxygen partial pressure: four years experience with 125 microsurgical transplants. J Craniomaxillofac Surg 2013; 41 (4): 303–9. DOI: 10.1016/j.jcms.2012.10.008
12. Mack J.M., Verkamp B., Richter G.T., Nicholas R., Stewart K., Crary S.E. Effect of sirolimus on coagulopathy of slow-flow vascular malformations. Pediatr Blood Cancer 2019; 66 (10): e27896. DOI: 10.1002/pbc.27896
13. Mazereeuw-Hautier J., Syed S., Leisner R.I., Harper J.I. Extensive venous/lymphatic malformations causing life-threatening haematological complications. Br J Dermatol 2007; 157 (3): 558–63. DOI: 10.1111/j.1365-2133.2007.08003.x
14. Sepúlveda P., Zavala A., Zúñiga P. Factors associated with thrombotic complications in pediatric patients with vascular malformations. J Pediatr Surg 2017; 52 (3): 400– 4. DOI: 10.1016/j.jpedsurg.2016.10.048
15. Ricci K.W., Chute C., Hammill A.M., Dasgupta R., Patel M. Retrospective study of hematologic complications in patients with slow-flow vascular malformations undergoing sclerotherapy. Pediatr Blood Cancer 2020; 67 (10): e28277. DOI: 10.1002/pbc.28277
16. Mack J.M., Pierce C.D., Richter G.T., Spray B.J., Nicholas R., Lewis P.S., et al. Analyzing coagulation dynamics during treatment of vascular malformations with thromboelastography. Pediatr Blood Cancer 2021; 68 (2): e28824. DOI: 10.1002/pbc.28824
17. Mason K.P., Neufeld E.J., Karian V.E., Zurakowski D., Koka B.V., Burrows P.E. Coagulation abnormalities in pediatric and adult patients after sclerotherapy or embolization of vascular anomalies. AJR Am J Roentgenol 2001; 177 (6): 1359–63. DOI: 10.2214/ajr.177.6.1771359
18. Garfein E., Doscher M., Tepper O., Gill J., Gorlick R., Smith R.V. Reconstruction of the pediatric midface following oncologic resection. J Reconstr Microsurg 2015; 31 (5): 336–42. DOI: 10.1055/s-0035-1544181
19. Arat Y.O., Mawad M.E., Boniuk M. Orbital venous malformations: current multidisciplinary treatment approach. Arch Ophthalmol 2004; 122 (8): 1151–8. DOI: 10.1001/archopht.122.8.1151
20. Callahan A.B., Meyers P.M., Garrity J.A., Son J.H., Petris C., Kazim M. Low-Flow Arterialized Venous Malformations of the Orbit. Ophthalmic Plast Reconstr Surg 2017; 33 (4): 256–60. DOI: 10.1097/IOP.0000000000000734
21. Dompmartin A., Acher A., Thibon P., Tourbach S., Hermans C., Deneys V., et al. Association of localized intravascular coagulopathy with venous malformations. Arch Dermatol 2008; 144 (7): 873–7. DOI: 10.1001/archderm.144.7.873
22. Ali S., Weiss C.R., Sinha A., Eng J., Mitchell S.E. The treatment of venous malformations with percutaneous sclerotherapy at a single academic medical center. Phlebology 2016; 31 (9): 603–9. DOI: 10.1177/0268355516633380
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Pediatric Hematology/Oncology and Immunopathology. 2024; 23: 174-181
The inftuence of thrombotic events in pediatric maxillofacial pathology on the results of surgical treatment
https://doi.org/10.24287/1726-1708-2024-23-4-174-181Abstract
Local and generalized thrombotic events can affect patient outcomes and quality of life. The purpose of our scoping review was to investigate the influence of thrombotic events in pediatric maxillofacial pathology on the results of surgical treatment. The search for publications was carried out in December 2023 in the PubMed information system. Two authors independently reviewed the studies and extracted data for analysis. The study included 8 publications out of 654 found. The pediatric cohort in the selected studies was mixed with adult patients. Insufficient information was obtained to carry out a meta-analysis and definitively answer the research question. It seems likely that the anatomical and pathophysiological features of maxillofacial pathology, pharmacological effects of therapy and methods of surgical correction may influence the development and progression of local intravascular coagulopathy. There are no recommendations on the choice of standard or integral hemostasis tests for the diagnosis and monitoring of coagulopathy in this pathology. The use of low-molecular-weight heparins can reduce the clinical manifestations of local intravascular coagulopathy.
References
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2. Martinelli I., Bucciarelli P., Mannucci P.M. Thrombotic risk factors: basic pathophysiology. Crit Care Med 2010; 38 (2 Suppl): S3–9. DOI: 10.1097/CCM.0b013e3181c9cbd9
3. Crochemore T., Görlinger K., Lance M.D. Early Goal-Directed Hemostatic Therapy for Severe Acute Bleeding Management in the Intensive Care Unit: A Narrative Review. Anesth Analg 2024; 138 (3): 499–513. DOI: 10.1213/ANE.0000000000006756
4. Tricco A.C., Lillie E., Zarin W., O'Brien K.K., Colquhoun H., Levac D., et al. PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation. Ann Intern Med 2018; 169 (7): 467–73. DOI: 10.7326/M18-0850
5. Rossell-Perry P. Flap Necrosis after Palatoplasty in Patients with Cleft Palate. Biomed Res Int 2015; 2015: 516375. DOI: 10.1155/2015/516375
6. Omesiete W.I., Walker J.A. 3rd, Yu J.C. Venous Thromboembolism Incidence After Craniofacial Surgery. Ann Plast Surg 2018; 80 (5): 561–4. DOI: 10.1097/SAP.0000000000001353
7. Forouzanfar T., Heymans M.W., van Schuilenburg A., Zweegman S., Schulten E.A. Incidence of venous thromboembolism in oral and maxillofacial surgery: a retrospective analysis. Int J Oral Maxillofac Surg 2010; 39 (3): 256–9. DOI: 10.1016/j.ijom.2009.10.024
8. Zhang C., Sun J., Zhu H., Xu L., Ji T., He Y., et al. Microsurgical free flap reconstructions of the head and neck region: Shanghai experience of 34 years and 4640 flaps. Int J Oral Maxillofac Surg 2015; 44 (6): 675– 84. DOI: 10.1016/j.ijom.2015.02.017
9. Hoffman G.R., Islam S., Eisenberg R.L. Microvascular reconstruction of the mouth, jaws, and face: experience of an Australian oral and maxillofacial surgery unit. J Oral Maxillofac Surg 2012; 70 (5): e371– 7. DOI: 10.1016/j.joms.2012.01.016
10. Jia Y., Zhao Y., Chen X. Clinical and histopathological review of 229 cases of ranula. J Huazhong Univ Sci Technolog Med Sci 2011; 31 (5): 717. DOI: 10.1007/s11596-011-0589-7
11. Jonas R., Schaal T., Krimmel M., Gülicher D., Reinert S., Hoffmann J. Monitoring in microvascular tissue transfer by measurement of oxygen partial pressure: four years experience with 125 microsurgical transplants. J Craniomaxillofac Surg 2013; 41 (4): 303–9. DOI: 10.1016/j.jcms.2012.10.008
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13. Mazereeuw-Hautier J., Syed S., Leisner R.I., Harper J.I. Extensive venous/lymphatic malformations causing life-threatening haematological complications. Br J Dermatol 2007; 157 (3): 558–63. DOI: 10.1111/j.1365-2133.2007.08003.x
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15. Ricci K.W., Chute C., Hammill A.M., Dasgupta R., Patel M. Retrospective study of hematologic complications in patients with slow-flow vascular malformations undergoing sclerotherapy. Pediatr Blood Cancer 2020; 67 (10): e28277. DOI: 10.1002/pbc.28277
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17. Mason K.P., Neufeld E.J., Karian V.E., Zurakowski D., Koka B.V., Burrows P.E. Coagulation abnormalities in pediatric and adult patients after sclerotherapy or embolization of vascular anomalies. AJR Am J Roentgenol 2001; 177 (6): 1359–63. DOI: 10.2214/ajr.177.6.1771359
18. Garfein E., Doscher M., Tepper O., Gill J., Gorlick R., Smith R.V. Reconstruction of the pediatric midface following oncologic resection. J Reconstr Microsurg 2015; 31 (5): 336–42. DOI: 10.1055/s-0035-1544181
19. Arat Y.O., Mawad M.E., Boniuk M. Orbital venous malformations: current multidisciplinary treatment approach. Arch Ophthalmol 2004; 122 (8): 1151–8. DOI: 10.1001/archopht.122.8.1151
20. Callahan A.B., Meyers P.M., Garrity J.A., Son J.H., Petris C., Kazim M. Low-Flow Arterialized Venous Malformations of the Orbit. Ophthalmic Plast Reconstr Surg 2017; 33 (4): 256–60. DOI: 10.1097/IOP.0000000000000734
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