Вопросы гематологии/онкологии и иммунопатологии в педиатрии. 2017; 16: 26-32
Результаты терапии сарком Юинга в Республике Беларусь
https://doi.org/10.24287/1726-1708-2017-16-2-26-32Аннотация
Список литературы
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12. Granowetter L., Womer R., Devidas M., Krailo M., Wang C., Bernstein M., et al. Dose-intensified compared with standard chemotherapy for nonmetastatic Ewing sarcoma family of tumours: a Children’s Oncology Group study. J Clin Oncol 2009; 27: 2536-41.
13. Oberlin O., Rey A., Desfachelles A.S., Philip T., Plantaz D., Schmitt C., et al. Impact of high-dose busulfan plus melphalan as consolidation in metastatic Ewing tumours: a study by the Societe Francaise des Cancers de l’Enfant. J Clin Oncol 2006; 24: 3997-4002.
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Pediatric Hematology/Oncology and Immunopathology. 2017; 16: 26-32
The treatment results of Ewing's sarcomas in children in Belarus Republic
https://doi.org/10.24287/1726-1708-2017-16-2-26-32Abstract
Chemotherapy and local control are mandatory components of treatment for patients with Ewing's sarcoma (ES). The aim of the study where the survival rates and clinical and pathological characteristics of patients with ES in the Belarus Republic (RB) over a 15-year. Data of ES patients (n=108) obtained from the RB children's cancer-registry (included in the International Agency for Research on Cancer, IARC) were used in the work. Event-free survival was superior for localized EES compared with metastatic forms (64,5% vs 19,5%; р < 0.0001). Patient characteristics: sex, age, level of lactate dehydrogenase, tumor size and location were characterized by a wide range and did not allow distinguish groups of favorable or unfavorable outcome. Treatment results for RB patients with ES are similar to generally accepted standards. Patients with metastatic status need new treatment strategies. Also new approaches are needed for identification and curate for third of patients with localized ES forms and unfavorable outcomes.
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