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Вопросы гематологии/онкологии и иммунопатологии в педиатрии. 2015; 14: 37-43

Билатеральный диффузный гиперпластический перилобарный нефробластоматоз: собственное клиническое наблюдение

Чилилова Асият Магомедовна, Качанов Денис Юрьевич, Митрофанова Анна Михайловна, Коновалов Дмитрий Михайлович, Сухов Максим Николаевич, Терещенко Галина Викторовна, Шаманская Татьяна Викторовна, Варфоломеева Светлана Рафаэлевна

https://doi.org/10.24287/1726-1708-2015-14-4-37-43

Аннотация

Нефробластоматоз - редкое предопухолевое состояние, ассоциированное с повышенным риском развития нефробластомы. В статье описан случай билатерального диффузного гиперпластического перилобарного нефробластоматоза у ребенка 10 мес. Обсуждаются вопросы классификации нефробластоматоза, дифференциальной диагностики нефробластоматоза и нефробластомы, представлены современные принципы терапии пациентов с данным заболеванием.
Список литературы

1. Pastore G, Znaor A, Spreafico F, Graf N, Pritchard-Jones K, Steliarova-Foucher E. Malignant renal tumours incidence and survival in European children (1978-1997): report from the Automated Childhood Cancer Information System project. Eur J Cancer. 2006; 42(13): 2103-14.

2. Bernstein L, Linet M, Smith MA, Olshan AF. Renal tumors. In: Ries LAG, Smith MA, Gurney JG, Linet M, Tamra T, Young JL, et al., eds. Cancer incidence and survival among children and adolescents: United States SEER Program 1975-1995, National Cancer Institute, SEER Program. NIH Pub. No. 99-4649. Bethesda, MD, 1999: 79-90.

3. Vujanic GM, Sandstedt B. The pathology of Wilms' tumour (nephroblastoma): the International Society of Paediatric Oncology approach. J Clin Pathol. 2010; 63(2): 102-9.

4. Beckwith JB. Precursor lesions of Wilms tumor: clinical and biological implications. Med Pediatr Oncol. 1993; 21(3): 158-68.

5. Perlman EJ, Faria P, Soares A, Hoffer F, Sredni S, Ritchey M, et al. Hyperplastic perilobar nephroblastomatosis: long-term survival of 52 patients. Pediatr Blood Cancer. 2006; 46(2): 203-21.

6. Hou LT, Holman RL. Bilateral nephroblastomatosis in a premature infant. J Pathol Bacteriol. 1961; 82: 249-55.

7. Hennigar RA, O'Shea PA, Grattan-Smith JD. Clinicopathologic features of nephrogenic rests and nephroblastomatosis. Adv Anat Pathol. 2001; 8(5): 276-89.

8. Rohrschneider WK, Weirich A, Rieden K, Darge K, Tröger J, Graf N. US, CT and MR imaging characteristics of nephroblastomatosis. Pediatr Radiol. 1998; 28(6): 435-43.

9. Rosenfield NS, Shimkin P, Berdon W, Barwick K, Glassman M, Siegel NJ. Wilms tumor arising from spontaneously regressing nephroblastomatosis. AJR Am J Roentgenol. 1980; 135(2): 381-4.

10. Wegert J, Bausenwein S, Kneitz S, Roth S, Graf N, Geissinger E, Gessler M. Retinoic acid pathway activity in Wilms tumors and characterization of biological responses in vitro. Mol Cancer. 2011; 10: 136.

11. Witt O, Hämmerling S, Stockklausner C, Schenk JP, Günther P, Behnisch W, et al. 13-cis retinoic acid treatment of a patient with chemotherapy refractory neph-roblastomatosis. J Pediatr Hematol Oncol. 2009; 31(4): 296-9.

Pediatric Hematology/Oncology and Immunopathology. 2015; 14: 37-43

Bilateral diffuse hyperplastic perilobar nephroblastomatosis: A case report

Chililova A. M., Kachanov D. Yu., Mitrofanova A. M., Konovalov D. M., Sukhov M. N., Tereshchenko G. V., Shamanskaya T. V., Varfolomeeva S. R.

https://doi.org/10.24287/1726-1708-2015-14-4-37-43

Abstract

Nephroblastomatosis is a rare congenital preneoplastic lesion associated with high risk of nephroblastoma (Wilms' tumor). A case report is presented: bilateral diffuse hyperplastic perilobar nephroblastomatosis in a 10-month-old infant. The classification of nephroblastomatosis, differential diagnosis of nephroblastomatosis and nephroblastoma, and current therapeutic strategies in patients with nephroblastomatosis are discussed.
References

1. Pastore G, Znaor A, Spreafico F, Graf N, Pritchard-Jones K, Steliarova-Foucher E. Malignant renal tumours incidence and survival in European children (1978-1997): report from the Automated Childhood Cancer Information System project. Eur J Cancer. 2006; 42(13): 2103-14.

2. Bernstein L, Linet M, Smith MA, Olshan AF. Renal tumors. In: Ries LAG, Smith MA, Gurney JG, Linet M, Tamra T, Young JL, et al., eds. Cancer incidence and survival among children and adolescents: United States SEER Program 1975-1995, National Cancer Institute, SEER Program. NIH Pub. No. 99-4649. Bethesda, MD, 1999: 79-90.

3. Vujanic GM, Sandstedt B. The pathology of Wilms' tumour (nephroblastoma): the International Society of Paediatric Oncology approach. J Clin Pathol. 2010; 63(2): 102-9.

4. Beckwith JB. Precursor lesions of Wilms tumor: clinical and biological implications. Med Pediatr Oncol. 1993; 21(3): 158-68.

5. Perlman EJ, Faria P, Soares A, Hoffer F, Sredni S, Ritchey M, et al. Hyperplastic perilobar nephroblastomatosis: long-term survival of 52 patients. Pediatr Blood Cancer. 2006; 46(2): 203-21.

6. Hou LT, Holman RL. Bilateral nephroblastomatosis in a premature infant. J Pathol Bacteriol. 1961; 82: 249-55.

7. Hennigar RA, O'Shea PA, Grattan-Smith JD. Clinicopathologic features of nephrogenic rests and nephroblastomatosis. Adv Anat Pathol. 2001; 8(5): 276-89.

8. Rohrschneider WK, Weirich A, Rieden K, Darge K, Tröger J, Graf N. US, CT and MR imaging characteristics of nephroblastomatosis. Pediatr Radiol. 1998; 28(6): 435-43.

9. Rosenfield NS, Shimkin P, Berdon W, Barwick K, Glassman M, Siegel NJ. Wilms tumor arising from spontaneously regressing nephroblastomatosis. AJR Am J Roentgenol. 1980; 135(2): 381-4.

10. Wegert J, Bausenwein S, Kneitz S, Roth S, Graf N, Geissinger E, Gessler M. Retinoic acid pathway activity in Wilms tumors and characterization of biological responses in vitro. Mol Cancer. 2011; 10: 136.

11. Witt O, Hämmerling S, Stockklausner C, Schenk JP, Günther P, Behnisch W, et al. 13-cis retinoic acid treatment of a patient with chemotherapy refractory neph-roblastomatosis. J Pediatr Hematol Oncol. 2009; 31(4): 296-9.