Диарея у пациентов с инфекцией COVID-19
https://doi.org/10.22416/1382-4376-2020-30-6-51-56
Аннотация
Цель обзора: рассмотреть возможные причины диареи у больных с инфекцией COVID-19.
Основные положения. Помимо респираторных симптомов, у пациентов с инфекцией COVID-19 могут наблюдаться и жалобы со стороны желудочно-кишечного тракта, среди которых ведущее место занимает диарея. Данные о ее частоте колеблются от 2 до 40 %. Причины возникновения диареи могут быть связаны с непосредственным взаимодействием вируса с рецепторами ангиотензин-превращающего фермента 2 (АСЕ2) слизистой оболочки кишечника, его влиянием на кишечную микробиоту, побочными эффектами проводимой терапии. Возможность диареи выступать в качестве ведущего клинического симптома коронавирусной инфекции затрудняет своевременную диагностику заболевания. Данные литературы о влиянии диареи на течение инфекции COVID-19 противоречивы.
Заключение: эпидемиологические и клинические аспекты данной проблемы требуют дальнейших исследований.
Об авторе
А. А. Шептулин
ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет) Министерства здравоохранения Российской Федерации
Россия
Россия
Шептулин Аркадий Александрович — доктор медицинских наук, профессор кафедры пропедевтики внутренних болезней Института клинической медицины им. Н.В. Склифософского
119991, г. Москва, ул. Погодинская, д. 1, стр. 1
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Рецензия
Для цитирования:
Шептулин А.А. Диарея у пациентов с инфекцией COVID-19. Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2020;30(6):51-56. https://doi.org/10.22416/1382-4376-2020-30-6-51-56
For citation:
Sheptulin A.A. Diarrhoea in Patients with COVID-19. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2020;30(6):51-56. (In Russ.) https://doi.org/10.22416/1382-4376-2020-30-6-51-56
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