Российский биотерапевтический журнал. 2015; 14: 3-8
РОЛЬ ЭПИТЕЛИАЛЬНО-МЕЗЕНХИМАЛЬНОГО ПЕРЕХОДА В РЕГУЛЯЦИИ СВОЙСТВ РАКОВЫХ СТВОЛОВЫХ КЛЕТОК СОЛИДНЫХ ОПУХОЛЕЙ
https://doi.org/10.17650/1726-9784-2015-14-4-3-8Аннотация
Список литературы
1. Arumugam Т, Ramachandran V., Fournier K.F. et al. Epithelial to mesenchymal transition contributes to dmg resistance in pancreatic cancer // Cancer Researsch. - 2009. - 69(14). - P. 5820-8.
2. Birchmeier W., Behrens J. Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness // Biochimica et Biophysica Acta. - 2006. - 1198. - P. 11-26.
3. Brabletz T., Hlubek F., Spaderna S. et al. Invasion and metastasis in colorectal cancer: epithelial- mesenchymal transition, mesenchymal- epithelial transition, stem cells and beta-catenin // Cells Tissues Organs. - 2003. - 179. - P. 56-65.
4. Chaffer C.L., Brueckmann I., Scheel C. et al. Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state // Proceedings of The National Academy of Sciences of The United States of America USA. -2011. - 108(19). -P. 7950-5.
5. Chaffer C.L., Marjanovic N.D., Lee T. et al. Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity // Cell. - 2013. - 154(1). - P. 61-74.
6. Chen J., Li Y, Yu T.S. et al. A restricted cell population propagates glioblastoma growth after chemotherapy // Nature. - 2012. - 488(7412). - P. 522-6.
7. Cole M.F., Johnson S.E., Newman J.J. et al. Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells // Genes & Development. - 2008. - 22(6). - P. 746-55.
8. Dahlrot R.H., Hermansen S.K., Hansen S., Kristensen B. W. What is the clinical value of cancer stem cell markers in gliomas? // International Journal of Clinical and Experimental Pathology. - 2013. - 6(3). - P. 334-48.
9. Dando l.;Cordani M:, Dalla Pozza E. et al. Antioxidant Mechanisms and ROS-Related MicroRNAs in Cancer Stem Cells // Oxidative Medicine and Cell Longevity. - 2015. - 2015. - P. 425708.
10. Graff J.R., Gabrielson E., Fujii H. et al. Methylation patterns of the E-cadherin 5' CpG island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression // Journal of Biological Chemistry. - 2000. - 275. - P. 2727-32.
11. Gonzalez-Moreno O., Lecanda J., Green J.E. et al. VEGF elicits epithelial-mesenchymal transition (EMT) in prostate intraepithelial neoplasia (PIN)-like cells via anautocrine loop // Experimental Cell Research. - 2010.-316(4).-P.554-67.
12. Gupta P.B., Fillmore C.M., Guozhi J. et al. Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells // Cell. - 2011. - 19. - P. 633-44.
13. Gupta P.B., Onder T.T., Jiang G. et al. Identification of selective inhibitors of cancer stem cells by high- throughput screening // Cell. - 2009. - 138. - P. 645-59.
14. Hamburger A. W. Salmon S.E. Primary bioassay of human tumor stem cells // Science. - 1977. - 197(4302). -P. 461-3.
15. Hanahan D., Coussens L.M. Accessories to crime: functions of cells recruited to tumor microenvironment // Cancer Cell. - 2012. - 21(3). - P. 309-22.
16. Heddleston J.M., Li Z., McLendon R.E. et al. The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype // Cell Cycle. - 2009. - 8(20). - P. 3274-84.
17. Hu Q., Zhang L. Wen J. et al. The EGF receptor-sox2-EGF receptor feedback loop positively regulates the self-renewal of neural precursorcells // Stem Cells. - 2010. - 28(2). - P. 279-86.
18. fkushima H, Todo T., fno Y. et al. Autocrine TGF-beta signaling maintains tumorigenicity of glioma- initiating cells through Siy-related HMG-boxfactors // Cell. Stem Cells. - 2009. - 5(5). - P. 504-14.
19. fliopoulos D., Hirsch H.A., Wang G. et al. Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion // Proceedings of The National Academy of Sciences of The United States of America USA. -2011. - 108(4). -P. 1397-402.
20. Jinushi M., Chiba S., Yoshiyama H. et al. Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells // Proceedings of The National Academy of Sciences of The United States of America. -2011. - 108(30). -P. 12425-30.
21. Khromova N., Kopnin P., Rybko V, Kopnin B.P. Downregulation of VEGF-C expression in lung and colon cancer cells decelerates tumor growth and inhibitsmetastasis via multiple mechanisms // Oncogene. - 2012. -31(11).-P. 1389-97.
22. Kurrey N.K., Jalgaonkar S.P., Joglekar А. V. et al. Snail and slug mediate radioresistance and chemoresis- tance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells // Stem Cells. - 2009. - 27(9). - P. 2059-68.
23. Lamb R., Ozsvari II. Lisanti C.L. et al. Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: treatingcancer like an infectious disease // Oncotarget. - 2015. - 6(7). - P. 4569-84.
24. Li Y, Laterra J. Cancer stem cells: distinct entities or dynamically regulated phenotypes? // Cancer Research. - 2012. - 73(3). - P. 576-80.
25. Lynch H.T., Grady W. Lynch J.F. et al. E-cadherin mutation-based genetic counseling and hereditary diffuse gastric carcinoma // Cancer Genet Cytogenet. - 2000. - 122. - P. 1-6.
26. Marson A., Foreman R., Chevalier B. et al. Wnt signaling promotes reprogramming of somatic cells to pluripotency // Cell. Stem Cell. - 2008. - 3(2). - P. 132-5.
27. Mirantes ( Espinosa I., Ferrer I. Epithelial-to-mesenchymal transition and stem cells in endometrial cancer // Human Pathology. - 2013. - 44(10). - P. 1973-81.
28. Naujokat (. Steinhart R. Salinomycin as a drug for targeting human cancer stem cells // Journal of Biomedicine and Biotechnology. - 2012. - 2012. - P. 950658.
29. O'Brien C., Kreso A., Jamieson H.M. Cancer stem cells and self-renewal // Clinical Cancer Research. - 2010.-47,-P. 1478-93.
30. Perez Cam M., Cobaleda C., Gonzalez Herrero I. et al. Cancer induction by restriction of oncogene expression to the stem cell compartment // The EMBO Journal. - 2009. - 28(1). - P. 8-20.
31. PerlA.K., Wilgenbus P., Dahl U. et al. A causal role for E-cadherin in the transition from adenoma to carci- noma//Nature. - 2009. - 392. - P. 190-3.
32. Po A., Ferretti E., Miele E. et al. Hedgehog controls neural stem cells through p53-independent regulation oh Nanog // The EMBO Journal. - 2010. - 29(15). - P. 2646-58.
33. Plaks V, KongN., Werb Z. The cancer stem cell niche: how essential is the niche in regulating sternness of tumor cells? // Cell Stem Cell. - 2015. - 16(3). - P. 225-38.
34. Rasheed Z.A., Yang J., Wang Q. et al. Prognostic significance of tumorigenic cells with mesenchymal features in pancreatic adenocarcinoma // Jomal of National Cancer Institution. - 2010. - 102(5). - P. 340-51.
35. Scheel C., Eaton E.N., Li S. et al. Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast // Cell. - 2011. - 145(6). - P. 926-40.
36. Shackleton M. Normal stem cells and cancer stem cells: similar and different // Seminars in Cancer Biology. -2010.-20.-P. 85-92.
37. Sineva G.S. Pospelov V.A. (3-Catenin in pluripotency: adhering to self-renewal or Wnting to differentiate? // International Review of Cell and Molecular Biology, - 2014. - 312. - P. 53-78.
38. Smalley M., Ashworth A. Stem cells and breast cancer: a field in transit // Nature Reviews: Cancer. - 2003. - 3(11).-P. 832-44.
39. Song I.S., Jeong Y.J., Han J. Mitochondrial metabolism in cancer stem cells: a therapeutic target for colon cancer//BMB Reports. -2015. -P. 3333.
40. Takebe N., Miele /. Harris P.J. et al. Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update // Nature Reviews. Clinical Oncology. - 2015. - 12(8). - P. 445-64.
41. Todaro M., Alea M.P., Di Stefano A.B. et al. Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4 // Cell Stem Cell. - 2007. - 1(4). - P. 389-402.
42. Vermeulen /. De Sousa E., Melo F. et al. Wnt activity defines colon cancer stem cells and is regulated by the microenvironment // Nature Cell Biology. - 2010. - 12(5). - P. 468-76.
43. Yi Z.Y., Feng L.J., Xiang Z., Yao H. Vascular endothelial growth factor receptor-1 activation mediates epithelial to mesenchymal transition inhepatocellular carcinoma cells // Journal of Investigative Surgery: the official journal of the Academy of Surgical Research. - 2011. - 24(2). - P. 67-76.
Russian Journal of Biotherapy. 2015; 14: 3-8
THE ROLE OF EPITHELIAL-MESENCHYMAL TRANSITION IN REGULATION OF SOLID TUMORS CANCER STEM CELLS CHARACTERISTICS
https://doi.org/10.17650/1726-9784-2015-14-4-3-8Abstract
References
1. Arumugam T, Ramachandran V., Fournier K.F. et al. Epithelial to mesenchymal transition contributes to dmg resistance in pancreatic cancer // Cancer Researsch. - 2009. - 69(14). - P. 5820-8.
2. Birchmeier W., Behrens J. Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness // Biochimica et Biophysica Acta. - 2006. - 1198. - P. 11-26.
3. Brabletz T., Hlubek F., Spaderna S. et al. Invasion and metastasis in colorectal cancer: epithelial- mesenchymal transition, mesenchymal- epithelial transition, stem cells and beta-catenin // Cells Tissues Organs. - 2003. - 179. - P. 56-65.
4. Chaffer C.L., Brueckmann I., Scheel C. et al. Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state // Proceedings of The National Academy of Sciences of The United States of America USA. -2011. - 108(19). -P. 7950-5.
5. Chaffer C.L., Marjanovic N.D., Lee T. et al. Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity // Cell. - 2013. - 154(1). - P. 61-74.
6. Chen J., Li Y, Yu T.S. et al. A restricted cell population propagates glioblastoma growth after chemotherapy // Nature. - 2012. - 488(7412). - P. 522-6.
7. Cole M.F., Johnson S.E., Newman J.J. et al. Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells // Genes & Development. - 2008. - 22(6). - P. 746-55.
8. Dahlrot R.H., Hermansen S.K., Hansen S., Kristensen B. W. What is the clinical value of cancer stem cell markers in gliomas? // International Journal of Clinical and Experimental Pathology. - 2013. - 6(3). - P. 334-48.
9. Dando l.;Cordani M:, Dalla Pozza E. et al. Antioxidant Mechanisms and ROS-Related MicroRNAs in Cancer Stem Cells // Oxidative Medicine and Cell Longevity. - 2015. - 2015. - P. 425708.
10. Graff J.R., Gabrielson E., Fujii H. et al. Methylation patterns of the E-cadherin 5' CpG island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression // Journal of Biological Chemistry. - 2000. - 275. - P. 2727-32.
11. Gonzalez-Moreno O., Lecanda J., Green J.E. et al. VEGF elicits epithelial-mesenchymal transition (EMT) in prostate intraepithelial neoplasia (PIN)-like cells via anautocrine loop // Experimental Cell Research. - 2010.-316(4).-P.554-67.
12. Gupta P.B., Fillmore C.M., Guozhi J. et al. Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells // Cell. - 2011. - 19. - P. 633-44.
13. Gupta P.B., Onder T.T., Jiang G. et al. Identification of selective inhibitors of cancer stem cells by high- throughput screening // Cell. - 2009. - 138. - P. 645-59.
14. Hamburger A. W. Salmon S.E. Primary bioassay of human tumor stem cells // Science. - 1977. - 197(4302). -P. 461-3.
15. Hanahan D., Coussens L.M. Accessories to crime: functions of cells recruited to tumor microenvironment // Cancer Cell. - 2012. - 21(3). - P. 309-22.
16. Heddleston J.M., Li Z., McLendon R.E. et al. The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype // Cell Cycle. - 2009. - 8(20). - P. 3274-84.
17. Hu Q., Zhang L. Wen J. et al. The EGF receptor-sox2-EGF receptor feedback loop positively regulates the self-renewal of neural precursorcells // Stem Cells. - 2010. - 28(2). - P. 279-86.
18. fkushima H, Todo T., fno Y. et al. Autocrine TGF-beta signaling maintains tumorigenicity of glioma- initiating cells through Siy-related HMG-boxfactors // Cell. Stem Cells. - 2009. - 5(5). - P. 504-14.
19. fliopoulos D., Hirsch H.A., Wang G. et al. Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion // Proceedings of The National Academy of Sciences of The United States of America USA. -2011. - 108(4). -P. 1397-402.
20. Jinushi M., Chiba S., Yoshiyama H. et al. Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells // Proceedings of The National Academy of Sciences of The United States of America. -2011. - 108(30). -P. 12425-30.
21. Khromova N., Kopnin P., Rybko V, Kopnin B.P. Downregulation of VEGF-C expression in lung and colon cancer cells decelerates tumor growth and inhibitsmetastasis via multiple mechanisms // Oncogene. - 2012. -31(11).-P. 1389-97.
22. Kurrey N.K., Jalgaonkar S.P., Joglekar A. V. et al. Snail and slug mediate radioresistance and chemoresis- tance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells // Stem Cells. - 2009. - 27(9). - P. 2059-68.
23. Lamb R., Ozsvari II. Lisanti C.L. et al. Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: treatingcancer like an infectious disease // Oncotarget. - 2015. - 6(7). - P. 4569-84.
24. Li Y, Laterra J. Cancer stem cells: distinct entities or dynamically regulated phenotypes? // Cancer Research. - 2012. - 73(3). - P. 576-80.
25. Lynch H.T., Grady W. Lynch J.F. et al. E-cadherin mutation-based genetic counseling and hereditary diffuse gastric carcinoma // Cancer Genet Cytogenet. - 2000. - 122. - P. 1-6.
26. Marson A., Foreman R., Chevalier B. et al. Wnt signaling promotes reprogramming of somatic cells to pluripotency // Cell. Stem Cell. - 2008. - 3(2). - P. 132-5.
27. Mirantes ( Espinosa I., Ferrer I. Epithelial-to-mesenchymal transition and stem cells in endometrial cancer // Human Pathology. - 2013. - 44(10). - P. 1973-81.
28. Naujokat (. Steinhart R. Salinomycin as a drug for targeting human cancer stem cells // Journal of Biomedicine and Biotechnology. - 2012. - 2012. - P. 950658.
29. O'Brien C., Kreso A., Jamieson H.M. Cancer stem cells and self-renewal // Clinical Cancer Research. - 2010.-47,-P. 1478-93.
30. Perez Cam M., Cobaleda C., Gonzalez Herrero I. et al. Cancer induction by restriction of oncogene expression to the stem cell compartment // The EMBO Journal. - 2009. - 28(1). - P. 8-20.
31. PerlA.K., Wilgenbus P., Dahl U. et al. A causal role for E-cadherin in the transition from adenoma to carci- noma//Nature. - 2009. - 392. - P. 190-3.
32. Po A., Ferretti E., Miele E. et al. Hedgehog controls neural stem cells through p53-independent regulation oh Nanog // The EMBO Journal. - 2010. - 29(15). - P. 2646-58.
33. Plaks V, KongN., Werb Z. The cancer stem cell niche: how essential is the niche in regulating sternness of tumor cells? // Cell Stem Cell. - 2015. - 16(3). - P. 225-38.
34. Rasheed Z.A., Yang J., Wang Q. et al. Prognostic significance of tumorigenic cells with mesenchymal features in pancreatic adenocarcinoma // Jomal of National Cancer Institution. - 2010. - 102(5). - P. 340-51.
35. Scheel C., Eaton E.N., Li S. et al. Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast // Cell. - 2011. - 145(6). - P. 926-40.
36. Shackleton M. Normal stem cells and cancer stem cells: similar and different // Seminars in Cancer Biology. -2010.-20.-P. 85-92.
37. Sineva G.S. Pospelov V.A. (3-Catenin in pluripotency: adhering to self-renewal or Wnting to differentiate? // International Review of Cell and Molecular Biology, - 2014. - 312. - P. 53-78.
38. Smalley M., Ashworth A. Stem cells and breast cancer: a field in transit // Nature Reviews: Cancer. - 2003. - 3(11).-P. 832-44.
39. Song I.S., Jeong Y.J., Han J. Mitochondrial metabolism in cancer stem cells: a therapeutic target for colon cancer//BMB Reports. -2015. -P. 3333.
40. Takebe N., Miele /. Harris P.J. et al. Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update // Nature Reviews. Clinical Oncology. - 2015. - 12(8). - P. 445-64.
41. Todaro M., Alea M.P., Di Stefano A.B. et al. Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4 // Cell Stem Cell. - 2007. - 1(4). - P. 389-402.
42. Vermeulen /. De Sousa E., Melo F. et al. Wnt activity defines colon cancer stem cells and is regulated by the microenvironment // Nature Cell Biology. - 2010. - 12(5). - P. 468-76.
43. Yi Z.Y., Feng L.J., Xiang Z., Yao H. Vascular endothelial growth factor receptor-1 activation mediates epithelial to mesenchymal transition inhepatocellular carcinoma cells // Journal of Investigative Surgery: the official journal of the Academy of Surgical Research. - 2011. - 24(2). - P. 67-76.
