Андрология и генитальная хирургия. 2024; 25: 16-23
Диффузионно-взвешенные изображения в диагностике рака предстательной железы: обзор литературы
Рзаев Р. Т., Бахтиозин Р. Ф., Рапопорт Л. М., Хэ М. , Еникеев М. Э., Королев Д. О., Амосов А. В.
https://doi.org/10.62968/2070-9781-2024-25-1-16-23Аннотация
Рак предстательной железы относится к числу наиболее распространенных онкологических заболеваний и занимает второе место по частоте встречаемости у мужчин в Российской Федерации. В связи с этим представляется актуальной своевременная и точная диагностика рака предстательной железы. Данный обзор литературы посвящен актуальности применения магнитно-резонансной томографии с получением диффузионно-взвешенных изображений в диагностике рака предстательной железы. В обзоре отображены современные диагностические методы, применяемые в первичной диагностике рака предстательной железы, стадировании заболевания, оценке ответа на терапию и выявлении рецидива. Авторами обсуждаются преимущества и недостатки метода и дальнейшие перспективы применения диффузионно-взвешенных изображений при обследовании пациентов с раком предстательной железы. Поиск литературы при подготовке настоящего обзора был выполнен с помощью электронных библиографических баз данных PubMed, E-library, Medline, Google Scholar.
Список литературы
1. Каприн А.Д., Алексеев Б.Я., Матвеев В.Б., Пушкарь Д.Ю., Говоров А.В., Горбань Н.А. и соавт. Рак предстательной железы. Клинические рекомендации. 2021.
2. Rider J. R., Wilson K. M., Sinnott J. A., Kelly R. S., Mucci L. A., Giovannucci E. L. Ejaculation Frequency and Risk of Prostate Cancer: Updated Results with an Additional Decade of Follow-up. European Urology. 2016; 70(6), 974–982. DOI:10.1016/j.eururo. 2016.03.027.
3. Каприн А.Д., Старинский В.В., Шахзадова А.О. Злокачественные новообразования в России в 2021 году (заболеваемость и смертность). ФГБУ «МНИОИ им. П.А. Герцена» Минздрава России. 2022.
4. Qayyum A. Diffusion-weighted Imaging in the Abdomen and Pelvis: Concepts and Applications. RadioGraphics. 2009; 29(6), 1797–1810. DOI:10.1148/rg.296095521.
5. Бахтиозин Р. Ф., Сафиуллин Р. Р. Диффузионно-взвешенное изображение всего тела в диагностике онкологических заболеваний. Russian Electronic Journal of Radiology (REJR). 2011; 1(2).
6. Le Bihan D., Breton E., Lallemand D., Grenier P., Cabanis E., Laval-Jeantet, M. MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders. Radiology. 1986; 161(2), 401–407. DOI:10.1148/radiology.161.2.3763909.
7. Koh D.-M., Collins D. J. Diffusion-Weighted MRI in the Body: Applications and Challenges in Oncology. American Journal of Roentgenology. 2007; 188(6), 1622–1635. DOI:10.2214/ajr.06.1403.
8. Koh D.-M., Blackledge M., Padhani A. R., Takahara T., Kwee T. C., Leach M. O. et al. Whole-Body DiffusionWeighted MRI: Tips, Tricks, and Pitfalls. American Journal of Roentgenology. 2012; 199(2), 252–262. DOI:10.2214/ajr.11.7866.
9. Ueno Y. R., Tamada T., Takahashi S., Tanaka U., Sofue K., Kanda T. et al. Computed Diffusion-Weighted Imaging in Prostate Cancer: Basics, Advantages, Cautions, and Future Prospects. Korean Journal of Radiology. 2018; 19(5), 832. DOI:10.3348/kjr.2018.19.5.832.
10. Коробкин А.С., Шария М.А., Чабан А.С., Восканян Г.А., Винаров А.З. Магнитно-резонансная семиотика рака предстательной железы в соответствии с классификацией PI-RADS. Клинико-диагностический алгоритм исследования. Вестник рентгенологии и радиологии. 2015; 4.
11. Ren J., Yang Y., Zhang J., Xu J., Liu Y., Wei M. et al. T2-weighted combined with diffusion-weighted images for evaluating prostatic transition zone tumors at 3 Tesla. Future Oncology. 2013; 9(4), 585–593. DOI:10.2217/fon.13.14.
12. Barrett T., Turkbey B., Choyke P.L. PI-RADS version 2: what you need to know. Clinical Radiology. 2015;70(11):1165Р76. DOI: 10.1016/j.crad.2015.06.093
13. Maurer M. H., Heverhagen J. T. Diffusion weighted imaging of the prostate—principles, application, and advances. Translational Andrology and Urology. 2017; 6(3), 490–498. DOI:10.21037/tau.2017.05.06.
14. Katahira K., Takahara T., Kwee T. C., Oda S., Suzuki Y., Morishita S. et al. Ultra-high-b-value diffusion-weighted MR imaging for the detection of prostate cancer: evaluation in 201 cases with histopathological correlation. European Radiology. 2010; 21(1), 188–196. DOI:10.1007/s00330-010-1883-7.
15. Rosenkrantz A. B., Parikh N., Kierans A. S., Kong M. X., Babb J. S., Taneja S. S. et al. Prostate Cancer Detection Using Computed Very High b-value Diffusion-weighted Imaging: How High Should We Go? Academic Radiology. 2016; 23(6), 704–711. DOI:10.1016/j.acra.2016.02.003.
16. Verma S., Rajesh A., Morales H., Lemen L., Bills G., Delworth M. et al. Assessment of Aggressiveness of Prostate Cancer: Correlation of Apparent Diffusion Coefficient With Histologic Grade After Radical Prostatectomy. American Journal of Roentgenology. 2011; 196(2), 374–381. DOI:10.2214/ajr.10.4441.
17. Vargas H. A., Akin O., Franiel T., Mazaheri Y., Zheng J., Moskowitz C. et al. Diffusion-weighted Endorectal MR Imaging at 3 T for Prostate Cancer: Tumor Detection and Assessment of Aggressiveness. Radiology. 2011; 259(3), 775–784. DOI:10.1148/radiol.11102066.
18. Lawrence E. M., Gallagher F. A., Barrett T., Warren A. Y., Priest A. N., Goldman D. A. et al. Preoperative 3-T DiffusionWeighted MRI for the Qualitative and Quantitative Assessment of Extracapsular Extension in Patients With Intermediate- or High-Risk Prostate Cancer. American Journal of Roentgenology. 2014; 203(3), W280–W286. DOI:10.2214/ajr.13.11754.
19. Kim C. K., Choi D., Park B. K., Kwon G. Y., Lim H. K. Diffusion-weighted MR imaging for the evaluation of seminal vesicle invasion in prostate cancer: Initial results. Journal of Magnetic Resonance Imaging. 2018; 28(4), 963–969. DOI:10.1002/jmri.21531.
20. Ren J., Huan Y., Wang H., Ge Y., Chang Y., Yin H., Sun L. Seminal vesicle invasion in prostate cancer: prediction with combined T2- weighted and diffusion-weighted MR imaging. European Radiology. 2009; 19(10), 2481–2486. DOI:10.1007/s00330-009-1428-0.
21. Yoshida S., Takahara T., Arita Y., Sakaino S., Katahira K., Fujii Y. Whole‐body diffusion‐weighted magnetic resonance imaging: Diagnosis and follow up of prostate cancer and beyond. International Journal of Urology. 2021; 28(5), 502–513. Portico. DOI:10.1111/iju.14497.
22. Padhani A. R., Liu G., Mu-Koh D., Chenevert T. L., Thoeny H. C., Takahara T. et al. Diffusion-Weighted Magnetic Resonance Imaging as a Cancer Biomarker: Consensus and Recommendations. Neoplasia. 2009; 11(2), 102–125. DOI:10.1593/neo.81328.
23. Eiber M., Holzapfel K., Ganter C., Epple K., Metz S., Geinitz H. et al. Whole-body MRI including diffusion-weighted imaging (DWI) for patients with recurring prostate cancer: Technical feasibility and assessment of lesion conspicuity in DWI. Journal of Magnetic Resonance Imaging. 2011; 33(5), 1160–1170. DOI:10.1002/jmri.22542.
24. Сергеев Н.И., Котляров П.М., Солодкий В.А. Диффузионно-взвешенные изображения в диагностике метастатического поражения позвоночника и костей таза. Сибирский онкологический журнал 2012; 6(54):68Р72. [Sergeev N.I., Kotlyarov P.M., Solodkiy V.A. Diffusion-weighted magnetic resonance image in diagnosis of metastatic cancer of the spinal column and pelvic bones. Sibirskiy onkologicheskiy zhurnal = Siberian Journal of Oncology 2012;6(54):68Р72. (In Russ.)
25. Lecouvet F. E., El Mouedden J., Collette L., Coche E., Danse E., Jamar F. et al. Can Whole-body Magnetic Resonance Imaging with Diffusion-weighted Imaging Replace Tc 99m Bone Scanning and Computed Tomography for Single-step Detection of Metastases in Patients with High-risk Prostate Cancer? European Urology. 2012; 62(1), 68–75. DOI:10.1016/j.eururo.2012.02.020.
26. Johnston E. W., Latifoltojar A., Sidhu H. S., Ramachandran N., Sokolska M., Bainbridge A. et al. Multiparametric wholebody 3.0-T MRI in newly diagnosed intermediate- and high-risk prostate cancer: diagnostic accuracy and interobserver agreement for nodal and metastatic staging. European Radiology. 2019; 29(6): 3159–3169. DOI:10.1007/s00330-018-5813-4
27. Budiharto T., Joniau S., Lerut E., Van den Bergh L., Mottaghy F., Deroose C. M. et al. Prospective Evaluation of 11C-Choline Positron Emission Tomography/Computed Tomography and Diffusion-Weighted Magnetic Resonance Imaging for the Nodal Staging of Prostate Cancer with a High Risk of Lymph Node Metastases. European Urology. 2011; 60(1), 125–130. DOI:10.1016/j.eururo.2011.01.015.
28. Zhou J., Gou Z., Wu R., Yuan Y., Yu G., Zhao Y. Comparison of PSMA-PET/CT, choline-PET/CT, NaF-PET/CT, MRI, and bone scintigraphy in the diagnosis of bone metastases in patients with prostate cancer: a systematic review and meta-analysis. Skeletal Radiology. 2019; 48(12):1915-1924. DOI:10.1007/s00256-019-03230-z.
29. Sandgren K., Westerlinck P., Jonsson J.H., Blomqvist L., Thellenberg Karlsson C., Nyholm T. et al. Imaging for the Detection of Locoregional Recurrences in Biochemical Progression After Radical Prostatectomy-A Systematic Review. European Urology Focus. 2019; 5:550–60. DOI: 10.1016/j.euf.2017.11.001.
30. Panebianco V., Barchetti F., Sciarra A., Musio D., Forte V., Gentile V. et al. Prostate Cancer Recurrence After Radical Prostatectomy: The Role of 3-T Diffusion Imaging in MultiParametric Magnetic Resonance Imaging. European Radiology. 2013; 23:1745–52. DOI: 10.1007/s00330-013-2768-3
31. Kwon T., Kim J.K., Lee C., Jung J., Ahn H., Kim C.S. et al. Discrimination of Local Recurrence After Radical Prostatectomy: Value of Diffusion-Weighted Magnetic Resonance Imaging. Prostate International. 2018; 6:12–7. DOI: 10.1016/j.prnil.2017.05.002.
32. Субботин Ю.А., Бахтиозин Р.Ф. Последние достижения магнитно-резонансной томографии всего тела в онкологии. REJR. 2018; 8(3):74-82. DOI:10.21569/2222-7415-2018-8-3-74-82.
Andrology and Genital Surgery. 2024; 25: 16-23
Diffusion-weighted imaging in diagnosis of prostate cancer: a review
Rzaev R. T., Bakhtiozin R. F., Rapoport L. M., He M. , Enikeev M. E., Korolev D. O., Amosov A. V.
https://doi.org/10.62968/2070-9781-2024-25-1-16-23Abstract
Prostate cancer is one of the most common cancers and ranks second in frequency among men in the Russian Federation. In this regard, timely and accurate diagnosis of prostate cancer seems relevant. This review is devoted to the relevance of using magnetic resonance imaging with diffusion-weighted images in the diagnosis of prostate cancer. The review represents modern diagnostic methods used in the primary diagnosis of prostate cancer, disease staging, assessment of response to therapy and detection of cancer recurrence. The authors discuss the advantages and disadvantages of the method, and further prospects for the use of diffusion-weighted images in the examination of patients with prostate cancer. The search for the preparation of this review was performed using electronic bibliographic databases PubMed, E-library, Medline, Google Scholar.
References
1. Kaprin A.D., Alekseev B.Ya., Matveev V.B., Pushkar' D.Yu., Govorov A.V., Gorban' N.A. i soavt. Rak predstatel'noi zhelezy. Klinicheskie rekomendatsii. 2021.
2. Rider J. R., Wilson K. M., Sinnott J. A., Kelly R. S., Mucci L. A., Giovannucci E. L. Ejaculation Frequency and Risk of Prostate Cancer: Updated Results with an Additional Decade of Follow-up. European Urology. 2016; 70(6), 974–982. DOI:10.1016/j.eururo. 2016.03.027.
3. Kaprin A.D., Starinskii V.V., Shakhzadova A.O. Zlokachestvennye novoobrazovaniya v Rossii v 2021 godu (zabolevaemost' i smertnost'). FGBU «MNIOI im. P.A. Gertsena» Minzdrava Rossii. 2022.
4. Qayyum A. Diffusion-weighted Imaging in the Abdomen and Pelvis: Concepts and Applications. RadioGraphics. 2009; 29(6), 1797–1810. DOI:10.1148/rg.296095521.
5. Bakhtiozin R. F., Safiullin R. R. Diffuzionno-vzveshennoe izobrazhenie vsego tela v diagnostike onkologicheskikh zabolevanii. Russian Electronic Journal of Radiology (REJR). 2011; 1(2).
6. Le Bihan D., Breton E., Lallemand D., Grenier P., Cabanis E., Laval-Jeantet, M. MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders. Radiology. 1986; 161(2), 401–407. DOI:10.1148/radiology.161.2.3763909.
7. Koh D.-M., Collins D. J. Diffusion-Weighted MRI in the Body: Applications and Challenges in Oncology. American Journal of Roentgenology. 2007; 188(6), 1622–1635. DOI:10.2214/ajr.06.1403.
8. Koh D.-M., Blackledge M., Padhani A. R., Takahara T., Kwee T. C., Leach M. O. et al. Whole-Body DiffusionWeighted MRI: Tips, Tricks, and Pitfalls. American Journal of Roentgenology. 2012; 199(2), 252–262. DOI:10.2214/ajr.11.7866.
9. Ueno Y. R., Tamada T., Takahashi S., Tanaka U., Sofue K., Kanda T. et al. Computed Diffusion-Weighted Imaging in Prostate Cancer: Basics, Advantages, Cautions, and Future Prospects. Korean Journal of Radiology. 2018; 19(5), 832. DOI:10.3348/kjr.2018.19.5.832.
10. Korobkin A.S., Shariya M.A., Chaban A.S., Voskanyan G.A., Vinarov A.Z. Magnitno-rezonansnaya semiotika raka predstatel'noi zhelezy v sootvetstvii s klassifikatsiei PI-RADS. Kliniko-diagnosticheskii algoritm issledovaniya. Vestnik rentgenologii i radiologii. 2015; 4.
11. Ren J., Yang Y., Zhang J., Xu J., Liu Y., Wei M. et al. T2-weighted combined with diffusion-weighted images for evaluating prostatic transition zone tumors at 3 Tesla. Future Oncology. 2013; 9(4), 585–593. DOI:10.2217/fon.13.14.
12. Barrett T., Turkbey B., Choyke P.L. PI-RADS version 2: what you need to know. Clinical Radiology. 2015;70(11):1165R76. DOI: 10.1016/j.crad.2015.06.093
13. Maurer M. H., Heverhagen J. T. Diffusion weighted imaging of the prostate—principles, application, and advances. Translational Andrology and Urology. 2017; 6(3), 490–498. DOI:10.21037/tau.2017.05.06.
14. Katahira K., Takahara T., Kwee T. C., Oda S., Suzuki Y., Morishita S. et al. Ultra-high-b-value diffusion-weighted MR imaging for the detection of prostate cancer: evaluation in 201 cases with histopathological correlation. European Radiology. 2010; 21(1), 188–196. DOI:10.1007/s00330-010-1883-7.
15. Rosenkrantz A. B., Parikh N., Kierans A. S., Kong M. X., Babb J. S., Taneja S. S. et al. Prostate Cancer Detection Using Computed Very High b-value Diffusion-weighted Imaging: How High Should We Go? Academic Radiology. 2016; 23(6), 704–711. DOI:10.1016/j.acra.2016.02.003.
16. Verma S., Rajesh A., Morales H., Lemen L., Bills G., Delworth M. et al. Assessment of Aggressiveness of Prostate Cancer: Correlation of Apparent Diffusion Coefficient With Histologic Grade After Radical Prostatectomy. American Journal of Roentgenology. 2011; 196(2), 374–381. DOI:10.2214/ajr.10.4441.
17. Vargas H. A., Akin O., Franiel T., Mazaheri Y., Zheng J., Moskowitz C. et al. Diffusion-weighted Endorectal MR Imaging at 3 T for Prostate Cancer: Tumor Detection and Assessment of Aggressiveness. Radiology. 2011; 259(3), 775–784. DOI:10.1148/radiol.11102066.
18. Lawrence E. M., Gallagher F. A., Barrett T., Warren A. Y., Priest A. N., Goldman D. A. et al. Preoperative 3-T DiffusionWeighted MRI for the Qualitative and Quantitative Assessment of Extracapsular Extension in Patients With Intermediate- or High-Risk Prostate Cancer. American Journal of Roentgenology. 2014; 203(3), W280–W286. DOI:10.2214/ajr.13.11754.
19. Kim C. K., Choi D., Park B. K., Kwon G. Y., Lim H. K. Diffusion-weighted MR imaging for the evaluation of seminal vesicle invasion in prostate cancer: Initial results. Journal of Magnetic Resonance Imaging. 2018; 28(4), 963–969. DOI:10.1002/jmri.21531.
20. Ren J., Huan Y., Wang H., Ge Y., Chang Y., Yin H., Sun L. Seminal vesicle invasion in prostate cancer: prediction with combined T2- weighted and diffusion-weighted MR imaging. European Radiology. 2009; 19(10), 2481–2486. DOI:10.1007/s00330-009-1428-0.
21. Yoshida S., Takahara T., Arita Y., Sakaino S., Katahira K., Fujii Y. Whole‐body diffusion‐weighted magnetic resonance imaging: Diagnosis and follow up of prostate cancer and beyond. International Journal of Urology. 2021; 28(5), 502–513. Portico. DOI:10.1111/iju.14497.
22. Padhani A. R., Liu G., Mu-Koh D., Chenevert T. L., Thoeny H. C., Takahara T. et al. Diffusion-Weighted Magnetic Resonance Imaging as a Cancer Biomarker: Consensus and Recommendations. Neoplasia. 2009; 11(2), 102–125. DOI:10.1593/neo.81328.
23. Eiber M., Holzapfel K., Ganter C., Epple K., Metz S., Geinitz H. et al. Whole-body MRI including diffusion-weighted imaging (DWI) for patients with recurring prostate cancer: Technical feasibility and assessment of lesion conspicuity in DWI. Journal of Magnetic Resonance Imaging. 2011; 33(5), 1160–1170. DOI:10.1002/jmri.22542.
24. Sergeev N.I., Kotlyarov P.M., Solodkii V.A. Diffuzionno-vzveshennye izobrazheniya v diagnostike metastaticheskogo porazheniya pozvonochnika i kostei taza. Sibirskii onkologicheskii zhurnal 2012; 6(54):68R72. [Sergeev N.I., Kotlyarov P.M., Solodkiy V.A. Diffusion-weighted magnetic resonance image in diagnosis of metastatic cancer of the spinal column and pelvic bones. Sibirskiy onkologicheskiy zhurnal = Siberian Journal of Oncology 2012;6(54):68R72. (In Russ.)
25. Lecouvet F. E., El Mouedden J., Collette L., Coche E., Danse E., Jamar F. et al. Can Whole-body Magnetic Resonance Imaging with Diffusion-weighted Imaging Replace Tc 99m Bone Scanning and Computed Tomography for Single-step Detection of Metastases in Patients with High-risk Prostate Cancer? European Urology. 2012; 62(1), 68–75. DOI:10.1016/j.eururo.2012.02.020.
26. Johnston E. W., Latifoltojar A., Sidhu H. S., Ramachandran N., Sokolska M., Bainbridge A. et al. Multiparametric wholebody 3.0-T MRI in newly diagnosed intermediate- and high-risk prostate cancer: diagnostic accuracy and interobserver agreement for nodal and metastatic staging. European Radiology. 2019; 29(6): 3159–3169. DOI:10.1007/s00330-018-5813-4
27. Budiharto T., Joniau S., Lerut E., Van den Bergh L., Mottaghy F., Deroose C. M. et al. Prospective Evaluation of 11C-Choline Positron Emission Tomography/Computed Tomography and Diffusion-Weighted Magnetic Resonance Imaging for the Nodal Staging of Prostate Cancer with a High Risk of Lymph Node Metastases. European Urology. 2011; 60(1), 125–130. DOI:10.1016/j.eururo.2011.01.015.
28. Zhou J., Gou Z., Wu R., Yuan Y., Yu G., Zhao Y. Comparison of PSMA-PET/CT, choline-PET/CT, NaF-PET/CT, MRI, and bone scintigraphy in the diagnosis of bone metastases in patients with prostate cancer: a systematic review and meta-analysis. Skeletal Radiology. 2019; 48(12):1915-1924. DOI:10.1007/s00256-019-03230-z.
29. Sandgren K., Westerlinck P., Jonsson J.H., Blomqvist L., Thellenberg Karlsson C., Nyholm T. et al. Imaging for the Detection of Locoregional Recurrences in Biochemical Progression After Radical Prostatectomy-A Systematic Review. European Urology Focus. 2019; 5:550–60. DOI: 10.1016/j.euf.2017.11.001.
30. Panebianco V., Barchetti F., Sciarra A., Musio D., Forte V., Gentile V. et al. Prostate Cancer Recurrence After Radical Prostatectomy: The Role of 3-T Diffusion Imaging in MultiParametric Magnetic Resonance Imaging. European Radiology. 2013; 23:1745–52. DOI: 10.1007/s00330-013-2768-3
31. Kwon T., Kim J.K., Lee C., Jung J., Ahn H., Kim C.S. et al. Discrimination of Local Recurrence After Radical Prostatectomy: Value of Diffusion-Weighted Magnetic Resonance Imaging. Prostate International. 2018; 6:12–7. DOI: 10.1016/j.prnil.2017.05.002.
32. Subbotin Yu.A., Bakhtiozin R.F. Poslednie dostizheniya magnitno-rezonansnoi tomografii vsego tela v onkologii. REJR. 2018; 8(3):74-82. DOI:10.21569/2222-7415-2018-8-3-74-82.
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