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Андрология и генитальная хирургия. 2013; 14: 7-16

Актуальные вопросы оказания помощи парам с мужским фактором бездетного брака: клинические и организационно-методические аспекты

Божедомов Владимир Александрович, Рохликов И. М., Третьяков А. А., Липатова Н. А., Виноградов И. В., Никонов Е. Л.

https://doi.org/10.17650/2070-9781-2013-4-7-16

Аннотация

Статья посвящена рассмотрению актуальных вопросов этиопатогенеза, диагностики, профилактики и  лечения нарушений репродуктивной функции у мужчин на основе междисциплинарного подхода с учетом клинических и организационно-методических аспектов. Предложена трехуровневая система оказания помощи мужчинам из бездетных пар. Отражены современные требования к оснащению андрологических лабораторий и методам оценки качества спермы. Обосновано выделение 3 этапов комплексной профилактики нарушений репродуктивной функции мужчин.

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Andrology and Genital Surgery. 2013; 14: 7-16

Topical problems of care rendered to childless couples with male factor infertility: сlinical, organizational, and methodical aspects

Bozhedomov V. A., Rohklikov I. M., Tretyakov A. A., Lipatova N. A., Vinogradov I. V., Nikonov E. L.

https://doi.org/10.17650/2070-9781-2013-4-7-16

Abstract

The paper considers the topical problems of the etiopathogenesis, diagnosis, prevention, and treatment of male reproductive dysfunction, by using an interdisciplinary approach in view of clinical, organizational, and methodical aspects. It proposes a three-level care system for men from childless couples. Current requirements for andrology laboratory equipment and sperm quality assessment methods are shown. Identification of 3 steps of comprehensive prevention of male reproductive dysfunction is substantiated.

References

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19. Gannon J.R., Emery B.R., Jenkins T.G., Carrell D.T. The sperm epigenome: implications for the embryo. Adv Exp Med Biol 2013;791:53–66.

20. Robinson L., Gallos I.D., Conner S.J. et al. The effect of sperm DNA fragmentation on miscarriage rates: a systematic review and meta-analysis. Hum Reprod 2012;27(10):2908–17.

21. Varshini J., Srinag B.S., Kalthur G. et al. Poor sperm quality and advancing age are associated with increased sperm DNA damage in infertile men. Andrologia 2012;44:642–9.

22. Koskimies A.I., Savander M., Ann-Marie N. et al. Sperm DNA damage and male infertility. Duodecim

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31. Snow-Lisy D., Sabanegh E. Jr. What does the clinician need from an andrology laboratory? Front Biosci (Elite Ed) 2013;1(5):289–304.

32. Evers J.L., Collins J.A. Surgery or embolisation for varicocele in subfertile men. Cochrane Database Syst Rev 2004;(3):CD000479.

33. Baazeem A., Belzile E., Ciampi A. et al. Varicocele and male factor infertility treatment: a new metaanalysis and review of the role of varicocele repair. Eur Urol 2011;60(4):796–808.

34. Kroese A.C., de Lange N.M., Collins J., Evers J.L. Surgery or embolization for varicoceles in subfertile men. Cochrane Database Syst Rev 2012 Oct 17;10:CD000479.

35. Ficarra V., Crestani A., Novara G., Mirone V. Varicocele repair for infertility: what is the evidence? Curr Opin Urol 2012;22(6):489–94.

36. Schauer I., Madersbacher S., Jost R. et al. The impact of varicocelectomy on sperm parameters: a meta-analysis. J Urol 2012;187(5):1540–7.

37. Wang Y.J., Zhang R.Q., Lin Y.J. et al. Relationship between varicocele and sperm DNA damage and the effect of varicocele repair: a meta-analysis. Reprod Biomed Online 2012;25(3):307–14.

38. Gorelick J.I., Goldstein M. Loss of fertility in men with varicocele. Fertil Steril 1971;22:469–74.

39. Redmon J.B., Carey P., Pryor J.L. Varicocele – the most common cause of male factor infertility? Hum Reprod Update 2002;8(1):53–8.

40. Will M.A., Swain J., Fode M. et al. The great debate: varicocele treatment and impact on fertility. Fertil Steril 2011;95(3):841–52.

41. Choi W.S., Kim S.W. Current issues in varicocele management: a review. World J Mens Health 2013;31(1):12–20.

42. Prikaz Ministerstva zdravookhraneniya RF ot 30 avgusta 2012 g. № 107n «O poryadke ispol'zovaniya vspomogatel'nykh reproduktivnykh tekhnologii, protivopokazaniyakh i ogranicheniyakh k ikh primeneniyu».

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46. Van Steirteghem A., Bonduelle M., Devroey P. et al. Follow-up of children born after ICSI. Hum Reprod Update 2002;8(2):111–6.

47. Feuer S.K., Camarano L., Rinaudo P.F. ART and health: clinical outcomes and insights on molecular mechanisms from rodent studies. Mol Hum Reprod 2013;19(4):189–204.