Журналов:     Статей:        

Андрология и генитальная хирургия. 2022; 23: 96-102

Множественная стеатоцистома мошонки. Клиническое наблюдение

Щеплев П. А., Рапопорт Л. М., Королев Д. О., Горинова Д. М., Наумов Н. П.

https://doi.org/10.17650/2070-9781-2022-23-4-96-102

Аннотация

Множественная стеатоцистома представляет собой заболевание сально-волосяной единицы, характеризующееся множественными кожными кистами, содержащими кожное сало. Мы сообщаем о случае множественной стеатоцистомы мошонки у 64-летнего мужчины. Клиническая картина сопровождалась активным воспалительным процессом в виде боли, отека, гиперемии. Поражение присутствовало около 1 мес. Ранее у этого пациента была диагностирована множественная стеатоцистома в бедренной области, по поводу которой было проведено оперативное лечение.

В настоящее время такие сообщения в научных базах данных появляются спорадически. Мы представляем случай множественной стеатоцистомы мошоночной локализации в связи с ее редкостью.

Список литературы

1. AlSabbagh M.M. Steatocystoma multiplex: a review. J Dermatol Dermatol Surg 2016;20(2):91–9. DOI: 10.1016/j.jdds.2016.02.001

2. Lima A.M., Rocha S.P., Batista C.M. et al. Reis CM, Leal II, Azevedo LE. What is your diagnosis. Case for diagnosis. An Bras Dermatol 2011;86(1):165–6.

3. Laquer V.T., Wu J.J., Tournas J.A. et al. Pruritic bluish-black subcutaneous papules on the chest. Dermatol Online J 2008;14(3):14. DOI: 10.5070/D392w5x3b7

4. Chu D.H. Steatocystoma multiplex. Dermatol Online J 2003;9(4):18. DOI: 10.5070/D328s7d513

5. Mortazavi H., Taheri A., Mansoori P., Kani Z.A. Localized forms of steatocystoma multiplex: сase report and review of the literature. Dermatol Online J 2005;11(1):22. DOI: 10.5070/D306b1k17k

6. Oh S.W., Kim M.Y., Lee J.S., Kim S.C. Keratin 17 mutation in pachyonychiacongenita type 2 patient with early onset steatocystoma multiplex and Hutchinson-like tooth deformity. J Dermatol 2006;33(3):161–4. DOI: 10.1111/j.1346-8138.2006.00037.x

7. Covello S.P., Smith F.J., Sillevis Smitt J.H. et al. Keratin 17 mutations cause either steatocystoma multiplex or pachyonychia congenita type 2. Br J Dermatol 1998;139(3):475–80. DOI: 10.1046/j.1365-2133.1998.02413.x

8. Gürel M.S., Bitiren M., Özardalı İ. Steatokistoma multipleks. T Klin J Dermatol 2000;10:209–12.

9. Liu Q., Wu W., Lu J. et al. Steatocystoma multiplex is associated with the R94C mutation in the KRTl7 gene. Mol Med Rep 2015;12(4):5072–56. DOI: 10.3892/mmr.2015.4063

10. Irvine A.D., McLean W.H. Human keratin diseases: the increasing spectrum of disease and subtlety of the phenotype-genotype correlation. Br J Dermatol 1999;140(5):815–28. DOI: 10.1046/j.1365-2133.1999.02810.x

11. Kim S.J., Park H.J., Oh S.T. et al. A case of steatocystoma multiplex limited to scalp. Ann Dermatol 2009;21(1):106–09. DOI: 10.5021/ad.2009.21.1.106

12. Hurley H.J., LoPresti P.J. Steatocystoma multiplex. Arch Dermatol 1965;92(1):110–1.

13. Plewig G., Wolf H.H., Braun-Falco O. Steatocystoma multiplex: anatomic reevaluation, electron microscopy, and autoradiography. Arch Dermatol Res 1982;272(3–4):363–80. DOI: 10.1007/BF00509068

14. Kamra H.T., Gadgil P.A., Ovhal A.G., Narkhede R.R. Steatocystoma multiplex-a rare genetic disorder: a case report and review of the literature. J Clin Diagn Res 2013;7(1):166–8. DOI: 10.7860/JCDR/2012/4691.2698

15. Vivas A., Keri J. Steatocystoma multiplex. In: Acneiform eruptions in dermatology. A differential diagnosis. Ed. by J.A. Zeichner. NY: Springer, New York, 2014. P. 343–8. DOI: 10.1007/978-1-4614-8344-1_47

16. Cho S., Chang S.E., Choi J.H. et al. Clinical and histologic features of 64 cases of steatocystoma multiplex. J Dermatol 2002;29(3):152–6. DOI: 10.1111/j.1346-8138.2002.tb00238.x

17. Ohtake N., Kubota Y., Takayama O. et al. Relationship between steatocystoma multiplex and eruptive vellus hair cysts. J Am Acad Dermatol 1992;26(5 Pt 2):876–8. DOI: 10.1016/0190-9622(92)70127-2

18. Papakonstantinou E., Franke I., Gollnick H. Facial steatocystoma multiplex combined with eruptive vellus hair cysts: a hybrid? J Eur Acad Dermatol Venereo 2015;29(10):2051–3. DOI: 10.1111/jdv.12588

19. Karen J.K., Heller M., Wee S.A., Mikkilineni R. Eruptive vellus hair cysts. Dermatol Online J 2007:13(1):14. DOI: 10.5070/D37nh4m6jt

20. Tomková H., Fujimoto W., Arata J. Expression of keratins (K10 and K17) in steatocystoma multiplex, eruptive vellus hair cysts, and epidermoid and trichilemmal cysts. Am J Dermatopathol 1997;19(3):250–3. DOI: 10.1097/00000372-199706000-00008

21. Georgakopoulos J.R., Ighani A., Yeung J. Numerous asymptomatic dermal cysts: diagnosis and treatment of steatocystoma multiplex. Can Fam Physician 2018;64(12):892–9. PMID: 30541803.

Andrology and Genital Surgery. 2022; 23: 96-102

Steatocystoma multiplex of the scrotum. Clinical case

Scheplev P. A., Rapoport L. M., Korolev D. O., Gorinova D. M., Naumov N. P.

https://doi.org/10.17650/2070-9781-2022-23-4-96-102

Abstract

Steatocystoma multiplex is a disorder of the pilosebaceous unit characterized by multiple sebum-containing dermal cysts. We report the case of a 64-year-old male presented with multiple skin-colored, partially hyperemic cystic located in the scrotum area. They were accompanied by an active inflammatory process in the form of pain, swelling, hyperemia. The lesion was present for about 1 month. Previously, this patient had diagnosed with multiple steatocystoma located in the hip area and received surgical treatment.

At present, such reports in the scientific databases are presented sporadically, therefore we report on multiple steatocystoma of the scrotal localization due to its rarity.

References

1. AlSabbagh M.M. Steatocystoma multiplex: a review. J Dermatol Dermatol Surg 2016;20(2):91–9. DOI: 10.1016/j.jdds.2016.02.001

2. Lima A.M., Rocha S.P., Batista C.M. et al. Reis CM, Leal II, Azevedo LE. What is your diagnosis. Case for diagnosis. An Bras Dermatol 2011;86(1):165–6.

3. Laquer V.T., Wu J.J., Tournas J.A. et al. Pruritic bluish-black subcutaneous papules on the chest. Dermatol Online J 2008;14(3):14. DOI: 10.5070/D392w5x3b7

4. Chu D.H. Steatocystoma multiplex. Dermatol Online J 2003;9(4):18. DOI: 10.5070/D328s7d513

5. Mortazavi H., Taheri A., Mansoori P., Kani Z.A. Localized forms of steatocystoma multiplex: sase report and review of the literature. Dermatol Online J 2005;11(1):22. DOI: 10.5070/D306b1k17k

6. Oh S.W., Kim M.Y., Lee J.S., Kim S.C. Keratin 17 mutation in pachyonychiacongenita type 2 patient with early onset steatocystoma multiplex and Hutchinson-like tooth deformity. J Dermatol 2006;33(3):161–4. DOI: 10.1111/j.1346-8138.2006.00037.x

7. Covello S.P., Smith F.J., Sillevis Smitt J.H. et al. Keratin 17 mutations cause either steatocystoma multiplex or pachyonychia congenita type 2. Br J Dermatol 1998;139(3):475–80. DOI: 10.1046/j.1365-2133.1998.02413.x

8. Gürel M.S., Bitiren M., Özardalı İ. Steatokistoma multipleks. T Klin J Dermatol 2000;10:209–12.

9. Liu Q., Wu W., Lu J. et al. Steatocystoma multiplex is associated with the R94C mutation in the KRTl7 gene. Mol Med Rep 2015;12(4):5072–56. DOI: 10.3892/mmr.2015.4063

10. Irvine A.D., McLean W.H. Human keratin diseases: the increasing spectrum of disease and subtlety of the phenotype-genotype correlation. Br J Dermatol 1999;140(5):815–28. DOI: 10.1046/j.1365-2133.1999.02810.x

11. Kim S.J., Park H.J., Oh S.T. et al. A case of steatocystoma multiplex limited to scalp. Ann Dermatol 2009;21(1):106–09. DOI: 10.5021/ad.2009.21.1.106

12. Hurley H.J., LoPresti P.J. Steatocystoma multiplex. Arch Dermatol 1965;92(1):110–1.

13. Plewig G., Wolf H.H., Braun-Falco O. Steatocystoma multiplex: anatomic reevaluation, electron microscopy, and autoradiography. Arch Dermatol Res 1982;272(3–4):363–80. DOI: 10.1007/BF00509068

14. Kamra H.T., Gadgil P.A., Ovhal A.G., Narkhede R.R. Steatocystoma multiplex-a rare genetic disorder: a case report and review of the literature. J Clin Diagn Res 2013;7(1):166–8. DOI: 10.7860/JCDR/2012/4691.2698

15. Vivas A., Keri J. Steatocystoma multiplex. In: Acneiform eruptions in dermatology. A differential diagnosis. Ed. by J.A. Zeichner. NY: Springer, New York, 2014. P. 343–8. DOI: 10.1007/978-1-4614-8344-1_47

16. Cho S., Chang S.E., Choi J.H. et al. Clinical and histologic features of 64 cases of steatocystoma multiplex. J Dermatol 2002;29(3):152–6. DOI: 10.1111/j.1346-8138.2002.tb00238.x

17. Ohtake N., Kubota Y., Takayama O. et al. Relationship between steatocystoma multiplex and eruptive vellus hair cysts. J Am Acad Dermatol 1992;26(5 Pt 2):876–8. DOI: 10.1016/0190-9622(92)70127-2

18. Papakonstantinou E., Franke I., Gollnick H. Facial steatocystoma multiplex combined with eruptive vellus hair cysts: a hybrid? J Eur Acad Dermatol Venereo 2015;29(10):2051–3. DOI: 10.1111/jdv.12588

19. Karen J.K., Heller M., Wee S.A., Mikkilineni R. Eruptive vellus hair cysts. Dermatol Online J 2007:13(1):14. DOI: 10.5070/D37nh4m6jt

20. Tomková H., Fujimoto W., Arata J. Expression of keratins (K10 and K17) in steatocystoma multiplex, eruptive vellus hair cysts, and epidermoid and trichilemmal cysts. Am J Dermatopathol 1997;19(3):250–3. DOI: 10.1097/00000372-199706000-00008

21. Georgakopoulos J.R., Ighani A., Yeung J. Numerous asymptomatic dermal cysts: diagnosis and treatment of steatocystoma multiplex. Can Fam Physician 2018;64(12):892–9. PMID: 30541803.