Андрология и генитальная хирургия. 2018; 19: 15-26
Механизм движения жгутиков сперматозоидов
https://doi.org/10.17650/2070-9781-2018-19-3-15-26Аннотация
Механизм движения ресничек и жгутиков сперматозоидов основан на скольжении дуплетов микротрубочек друг относительно друга благодаря поступательному движению динеинов – моторных белков, способных перемещаться по поверхности микротрубочек и трансформирующих химическую энергию, содержащуюся в аденозинтрифосфате, в механическую энергию движения. Ранее внешние и внутренние динеиновые ручки считали сходными по структуре и функциям, однако недавно полученные экспериментальные данные свидетельствуют о значительном их различии по составу субъединиц, расположению в аксонеме и механизмам регуляции. И хотя понимание принципов изменения активности описанных моторных белков остается неполным, установлены тонкие механизмы функционирования данных структур.
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Andrology and Genital Surgery. 2018; 19: 15-26
A mechanism of sperm cilia beating
https://doi.org/10.17650/2070-9781-2018-19-3-15-26Abstract
The basis of the mechanism of cilia and sperm flagella motility is the sliding of doublets of microtubules relative to each other due to translational movement of dyneins. Previously, external and internal dynein arm were considered similar in structure and functions, however, recent experimental data suggest a significant difference in the composition of subunits, axoneme location, and regulatory mechanisms. And although the understanding of the principles of changes in the activity of the described motor proteins remains incomplete, subtle mechanisms of the functioning of these structures have been established.
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