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Андрология и генитальная хирургия. 2012; 13: 54-61

Ультраструктурное исследование сперматозоидов у пациентов с астенозооспермией

Хаят С. Ш., Брагина Е. Е., Курило Любовь Федоровна

https://doi.org/10.17650/2070-9781-2012-4-54-61

Аннотация

Ультраструктура двигательного аппарата жгутика сперматозоида является высоко консервативной и состоит из ряда элементов цитоскелета, необходимых для обеспечения движения сперматозоида. Обсуждаются нарушения ультраструктурных механизмов у 86 пациентов с астенозооспермией.

Список литературы

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Andrology and Genital Surgery. 2012; 13: 54-61

Ultrastructural investigation of human sperm from asthenozoospermic men

Khayat S. Sh., Bragina E. E., Kurilo L. F.

https://doi.org/10.17650/2070-9781-2012-4-54-61

Abstract

Ultrastructure of the flagellum is highly conserved and is composed of a number of cytoskeletal elements whose proper assembly is critical for sperm motility. Ultrastructural mechanisms damage as cause of asthenozoospermia development are discussed.

References

1. Auger J., Dadoune J-P. Nuclear status of human sperm cells by transmission electron microscopy and image cytometry: changes in nuclear shape and chromatin texture during spermiogenesis and epididymal

2. transit. Biol Reprod 1993;49:166–75.

3. Cornwall G.A. New insights into epididymal biology and function. Hum Reprod Update 2009;15:213–27.

4. Baker M.A., Witherdin R., Hetherington L. et al. Identification of post-translational modifications that occur during sperm maturation using difference in two-dimensional gel electrophoresis. Proteomics 2005;5:1003–12.

5. Florman H.M., Ducibella T. Fertilization in mammals. In: Neil J.D. (ed.), The Physiology of Reproduction, vol. 1. St. Louis, MO: Elsevier-Academic Press, 2006. Pp. 55–112.

6. Zanetti N., Mayorga L.S. Acrosomal swelling and membrane docking are required for hybrid vesicle formation during the human sperm acrosome reaction. Biol Reprod 2009;81:396–405.

7. Xia J., Reigada D., Mitchell C.H., Ren D. CATSPER channel mediated Ca2+ entry into mouse sperm triggers a tail-to-head propagation. Biol Reprod 2007;77:551–9.

8. Buffone M., Ijuri T., Cao W. et al. Heads or tails? Structural events and molecular mechanisms that promote mammalian sperm acrosomal exocytosis and motility. Mol Repr Dev 2012;79:4–18.

9. Bartoov B., Eltes F., Pansky M. et al. Improved diagnosis of male fertility potential via a combination of quantitative ultramorphology and routine semen analyses. Hum Reprod 1994;9(11):2069–75.

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11. Henkel R.R. Leukocytes and oxidative stress: dilemma for sperm function and male fertility. Asian J Androl 2011;13(1):43–52.

12. Menkveld R., Huwe P., Ludwig M., Weidner W. Morphological sperm alterations in different types of prostatitis. Andrologia 2003;35:288–93.

13. Gianaroli L., Magli M.C., Collodel G. et al. Sperm head's birefringence: a new criterion for sperm selection. Fertil Steril 2008;90(1):104–12.

14. Ryder T.A., Mobberley M.A., Hughes L., Hendry W.F. A survey of the ultrastructural defects associated with absent or impaired human sperm motility. Fertil Steril 1990;53(3):556–60.

15. Chemes H.E., Alvarez S.C. Tales of the tail and sperm headaches: changing concepts on the prognostic significance of sperm pathologies affecting the head, neck and tail. Asian J Androl 2012;14(1):14–23.

16. Wilton L.J., Teichtahl H., Temple-Smith P.D., de Kretser D.M. Structural heterogeneity of the axonemes of respiratory cilia and sperm flagella in normal men. J Clin Invest 1985;75(3):825–31.

17. Chia S.E., Lim T. A., Tay S.K., Lim S.T. Factors associated with male infertility: a case-control study of 218 infertile and 240 fertile men. BJOG 2000;107(1):55–61.

18. Williamson R.A., Koehler J.K., Smith W.D., Stenchever M.A. Ultrastructural sperm tail defects associated with sperm immotility. Fertil Steril 1984;41(1):103–7.

19. Courtade M., Lagorce C., Bujan L. et al. Clinical characteristics and light and transmission electron microscopic sperm defects of infertile men with persistent unexplained asthenozoospermia. Fertil Steril

20. ;70(2):297–304.

21. Chemes E.H., Rawe Y.V. Sperm pathology: a step beyond descriptive morphology. Origin, characterization and fertility potential of abnormal sperm phenotypes in infertile men. Hum Reprod

22. Update 2003;9(5):405–28.

23. Chemes H.E., Rawe V.Y. The making of abnormal spermatozoa: cellular and molecular mechanisms underlying pathological spermiogenesis. Cell Tissue Res 2010;341(3):349–57.

24. Chemes H.E. Phenotypes of sperm pathology: genetic and acquired forms in infertile men. J Androl 2000;21(6):799–808.

25. Neiderberger C. Complete asthenospermia: to diagnose or not to diagnose? J Androl 2005;26(3):306–7.

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27. Dinastiya, 2007. S. 58–64.

28. Francavilla S., Cordeschi G., Pelliccione F. et al. Isolated teratozoospermia: a cause of male sterility in the era of ICSI? Front Biosci 2007; 1:69–88.