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Андрология и генитальная хирургия. 2015; 16: 63-68

Распространенность курения среди мужчин с бесплодием в браке и/или заболеваниями органов половой системы

Андреева М. В., Хаят С. Ш., Сорокина Т. М., Шилейко Л. В., Остроумова Т. В., Курило Л. Ф.

https://doi.org/10.17650/2070-9781-2015-1-63-68

Аннотация

Известно, что до половины факторов, негативно влияющих на здоровье населения, связаны с образом жизни. Одним из распространенных факторов риска возникновения различных заболеваний является курение. Для предотвращения последствий воздействия повреждающих факторов на будущие поколения необходимо изучение распространенности и влияния курения у супругов, планирующих зачатие ребенка. В 2012–2013 гг. мы обследовали и опросили 255 мужчин, обратившихся в связи с проблемами деторождения в браке и/или заболеваниями органов половой системы. Большинство респондентов проживали в Москве. Мужчинам предлагали ответить на вопросы о стаже курения, типе сигарет, числе выкуриваемых сигарет в день и др. Среди опрошенных никогда не курили 35 %, бросили курить 27 %. Курили на момент опроса 38 % мужчин, из них более 70 % – регулярно. Стаж курения 58 % регулярно курящих мужчин составлял более 10 лет, 35 % – 6 лет и более. Стаж курения у половины курящих от случая к случаю мужчин был 6 лет и более. Большинство регулярно курящих выкуривали 10–20 сигарет ежедневно. И регулярно, и время от времени курящие мужчины предпочитали «легкие» и «средние» по крепости сигареты. Среди бросивших курить 63 % мужчин имели стаж курения 6 лет и более. При этом на момент опроса время воздержания от курения у 54 % бывших курильщиков составляло менее года. Распространенность курения среди обследованных нами мужчин приблизительно на 20 % ниже, чем среди мужского населения в целом, по данным других исследователей. Предполагаем, что это связано с заботой мужчин, решивших стать отцами, о своем здоровье и здоровье будущего ребенка. Возможно также, что длительное ненаступление желанной беременности привело к пересмотру привычного образа жизни. С другой стороны, значительная часть опрошенных, несмотря на планирование беременности, не отказывается от вредной привычки и продолжает выкуривать более 10 сигарет в день. 

Список литературы

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Andrology and Genital Surgery. 2015; 16: 63-68

Smoking rates for men from infertile couples and men with reproductive disorders

Andreeva M. V., Khayat S. Sh., Sorokina T. M., Schileyko L. V., Ostroumova T. V., Kurilo L. F.

https://doi.org/10.17650/2070-9781-2015-1-63-68

Abstract

A number of lifestyle factors (such as smoking, alcohol abuse, etc.) are known to impact negatively overall health and wellbeing. Tobacco use is a risk factor for serious disease development. Still in the view of many scientists smoking is the easy preventable risk factor for some diseases. It is necessary to study the prevalence and influence of tobacco smoking on people who are planning to conceive a child in order to prevent the effects of damaging factors on future generations. In 2012–2013 years we questioned 255 men from infertile couples and men with proven reproductive disorders about their smoking experience, number of cigarettes smoked per day, type of cigarettes, etc. The majority of respondents were Moscow dwellers. Our survey found out that 35 % of the respondents have never smoked, 27 % quitted smoking; 38 % of the respondents smoked and 70 % of them do it regularly. The 58 % of regular smokers reported more than 10 years of smoking experience. A half of non-regular smokers have 6 or more years of smoking experience. Most of daily smokers consume more than half a pack cigarettes per day. Both regular and non-regular smokers preferred “light” and “medium” cigarettes. Among former smokers 63 % reported six or more years experience of smoking. It is typical that 54 % of quitters gave up smoking less than a year ago. The prevalence of smoking among men surveyed is more than 20 % lower than indicated for the whole country male population by most authors. We assume that it may be due to the care of men who plan to become fathers of their health and health of future children. Also long waiting time to pregnancy is likely to give rise to lifestyle habits reevaluation. On the other hand, a lot of respondents don,t give up the habit and continue to smoke more than ten cigarettes a day despite pregnancy planning. 

References

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2. Kurilo L.F. Sistema testirovaniya faktorov, povrezhdayushchikh zhenskie i muzhskie gamety i gonady. Gigiena i sanitariya 2011;(5):72–8. [Kurilo L.F. System of testing of factors that damage the male and female gametes and gonads. Gigiena i sanitariya = Hygiene and Sanitation 2011;(5):72–8. (In Russ.)].

3. O’Callaghan F.V., Al Mamun A., O Callaghan M. et al. Maternal smoking during pregnancy predicts nicotine disorder (dependence or withdrawal) in young adults – a birth cohort study. Aust N Z J Public Health 2009;33(4):371–7.

4. Chistyakov V., Patkina N., Tammimäki A. et al. Nicotine exposure through-out early development promotes nicotine self-administration in adolescent mice and induces long-lasting behavioural changes. Eur J Pharmacol 2010;640(1–3):87–93.

5. Rydell M., Cnattingius S., Granath F. et al. Prenatal exposure to tobacco and future nicotine dependence: population-based cohort study. Br J Psychiatry 2012;200(3):202–9.

6. Schneider T., Bizarro L., Asherson P.J., Stolerman I.P. Hyperactivity, increased nicotine consumption and impaired performance in the five-choice serial reaction time task in adolescent rats prenatally exposed to nicotine. Psychopharmacology 2012;223(4):401–15.

7. Kotysheva E.N. Vliyanie tabakokureniya roditeleĭ na prenatal'nyĭ morfogenez. Vestnik TGU. Seriya: Estestvennye i tekhnicheskie nauki 2006;11(4):518–9. [Kotysheva E.N. Influence of smoking of parents on prenatal morphogenesis. Vestnik TGU. Seriya: estestvennye i tekhnicheskiye nauki = Bulletin of the TSU. Series: Natural and Technical Sciences 2006;11(4):518–9. (In Russ.)].

8. Herrman M., King K., Weitzman M. Prenatal tobacco smoke and postnatal secondhand smoke exposure and child neurodevelopment. Curr Opin Pediatr 2008;20(2):184–90.

9. Hernandez-Martínez C., Arija Val V., Escribano Subías J., Canals Sans J. A longitudinal study on the effects of maternal smoking and secondhand smoke exposure during pregnancy on neonatal neurobehavior. Early Human Development 2012;88(6):403–8.

10. Maritz G.S., Harding R. Life-long programming implications of exposure to tobacco smoking and nicotine before and soon after birth: evidence for altered lung development. Int J Environ Res Public Health 2011;8(3):875–98.

11. Stroud L.R., Paster R.L., Goodwin M.S. et al. Maternal smoking during pregnancy and neonatal behavior: a large-scale community study. Pediatrics 2009;123(5):842–8.

12. Fenercioglu A.K., Tamer I., Karatekin G., Nuhoglu A. Impaired postnatal growth of infants prenatally exposed to cigarette smoking. J Exper Med 2009;218(3):221–8.

13. Jensen M.S., Toft G., Thulstrup A.M. et al. Cryptorchidism according to maternal gestational smoking. Epidemiology 2007;18(2):220–5.

14. Jensen T.K., Jørgensen N., Punab M. et al. Association of in utero exposure to maternal smoking with reduced semen quality and testis size in adulthood: a cross-sectional study of 1,770 young men from the general population in five European countries. Am J Epidemiol 2004; 159(1):49–58.

15. Chang G.Q., Karatayev O., Leibowitz S.F. et al. Prenatal exposure to nicotine stimulates neurogenesis of orexigenic peptide-expressing neurons in hypothalamus and amygdale. Journal of Neuroscience 2013;33(34):13600–11.

16. El-Nemr A., Al-Shawaf T., Sabatini L. et al. Effect of smoking on ovarian reserve and ovarian stimulation in in-vitro fertilization and embryo transfer. Hum Reprod 1998;13(8):2192–8.

17. Saraç F., Öztekin K., Çelebi G. Early menopause association with employment, smoking, divorced marital status and low leptin levels. Gynecol Endocrinol 2011;27(4):273–8.

18. Bolumar F., Olsen J., Boldsen J. Smoking reduces fecundity: a European multicenter study on infertility and subfecundity. The European Study Group on Infertility and Subfecundity. Am J Epidemiol 1996;143(6):578–87.

19. Augood C., Duckitt K., Templeton A.A. Smoking and female infertility: a systematic review and meta-analysis. Hum Reprod 1998;13(6):1532–9.

20. Klonoff-Cohen H. Female and male lifestyle habits and IVF: what is known and unknown. Hum Reprod Update 2005;11(2):179–203.

21. Soares S.R., Melo M.A. Cigarette smoking and reproductive function. Curr Opin Obstet Gynecol 2008;20(3):281–91.

22. Kinney A., Kline J., Levin B. Alcohol, caffeine and smoking in relation to age at menopause. Maturitas 2006;54(1):27–38.

23. Matikainen T., Perez G.L., Jurisicova A. et al. Aromatic hydrocarbon receptor-driven BAX gene expression is required for premature ovarian failure caused by biohazardous environmental chemicals. Nat Genet 2001;28(4):300–1.

24. Cinar O., Dilbaz S., Terzioglu F. et al. Does cigarette smoking really have detrimental effects on outcomes of IVF? Eur J Obstet Gynecol Reprod Biol 2014;174:106–10.

25. Hughes E.G., Young Lai E.V., Ward S.M. Cigarette smoking and outcomes of in-vitro fertilization and embryo transfer: a prospective cohort study. Hum Reprod 1992;7(3):358–61.

26. Ragheb A.M., Sabanegh E.S. Jr. Smoking and male fertility: a contemporary review. Arch Med Sci 2009;5(1A): 13–9.

27. Robbins W.A., Elashoff D.A., Xun L. et al. Effect of lifestyle exposures on sperm aneuploidy. Cytogenet Genome Res 2005;111(3–4):371–7.

28. Fraga C.G., Motchnik P.A., Wyrobek A.J. Smoking and low antioxidant levels increase oxidative damage to sperm DNA. Mutat Res 1996;351(2):199–203.

29. Zenzes M.T., Puy L.A., Bielecki R., Reed T.E. Detection of benzo[a]pyrene diol epoxide-DNA adducts in embryos from smoking couples: evidence for transmission by spermatozoa. Mol Hum Reprod 1999;5(2):125–31.

30. Potts R.J., Newbury C.J., Smith G. et al. Sperm chromatin damage associated with male smoking. Mutat Res 1999;423 (1–2):103–11.

31. Yauk C.L., Berndt M.L., Williams A. et al. Mainstream tobacco smoke causes paternal germ-line DNA mutation. Cancer Res 2007;67(11):5103–6.

32. Shende V., Singh P., Pawar S. et al. Effect of smoking on membrane integrity of sperms – study by hypo-osmotic swelling test. Int J Biol Med Res 2012;3(3):1909–11.

33. Baker T.G., Neal P. Action of ionizing radiations on the mammalian ovary. In: The ovary. 2nd edn. S. Zuckerman, B.J. Weir (eds.). New York, San Francisco & London: Acad Press, 1977. Pp. 1–47.

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